Uberaba to Assis is about 298 road miles (480 km): roughly 6 h 15 min at the wheel if you don't stop.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Driving on Brazil’s roads poses significant risks.”
| Total distance | 298 mi (480 km) |
|---|---|
| Driving time, no stops | 6 h 15 min |
| Main roads, in order | MG-427 → SP-413 → SP-265 → SP-425 → BR-153 → SP-333 |
| States on the route | Minas Gerais, São Paulo |
| Fuel estimate (car at 25 mpg) | about 11.9 gal; actual use varies by vehicle and traffic |
| Stops listed below | 3 |
The Uberaba–Assis drive in a few lines
BR-153 (107 mi) and SP-425 (77 mi) carry about 62% of the 298 miles. It runs through 2 states: Minas Gerais, São Paulo. None of the 3 stops below is right on the road, so plan each as a short side trip.
Which roads connect Uberaba and Assis
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–3 | 3 | Minas Gerais |
| MG-427 | 3–29 | 26 | Minas Gerais |
| connecting roads | 29–30 | 1 | Minas Gerais |
| SP-413 | 30–47 | 17 | Minas Gerais, São Paulo |
| SP-265 | 47–60 | 13 | São Paulo |
| SP-425 | 60–137 | 77 | São Paulo |
| BR-153 | 137–244 | 107 | São Paulo |
| SP-333 | 244–296 | 52 | São Paulo |
| local roads | 296–298 | 2 | São Paulo |
- Mile 31 of this route: Minas Gerais → São Paulo (state line)
Breaking up the drive: stops between Uberaba and Assis
- Museums and history: Museu Ruy Menezes (mile 84), Museu de Paleontologia de Marília (mile 253)
- With kids: Thermas dos Laranjais (mile 109)
Museu Ruy Menezes
In Barretos, São Paulo, the Ruy Menezes Historical, Artistic and Folkloric Museum safeguards the city's memory through documents and objects from local history.
Thermas dos Laranjais
Thermas dos Laranjais is a water park in the municipality of Olímpia, in São Paulo state, drawing more than two million visitors a year.
Museu de Paleontologia de Marília
One of the few museums in Brazil devoted entirely to paleontology, the Museu de Paleontologia de Marília is a science museum in Marília, São Paulo state.
Arriving in Assis
Estação de Assis
Assis's railway station joined the company's trunk line in 1914 and got its current building in 1926; the original station was adapted as housing for traffic staff in 1927.
Museu de Arte Primitiva de Assis
Assis's museum of primitive (naïve) art, founded by José Nazareno Mimessi, sits inside Parque do Buracão, an ecological park, in its own climate-controlled building opened in 1999. It is run by the city's culture department.
More drives to Assis
- Jaú to Assis
- Araraquara to Assis
- Ribeirão Preto to Assis
- São Paulo to Assis
- Mogi Guaçu to Assis
- Poços de Caldas to Assis
From Uberaba to other places in Brazil
- Uberaba to Paranapiacaba
- Uberaba to Cubatão
- Uberaba to Itanhaém
- Uberaba to São Vicente
- Uberaba to Jacareí
- Uberaba to Taubaté
Frequently asked questions
How long is the drive from Uberaba to Assis?
About 6 h 15 min of driving without stops, over 298 miles.
How far is Assis from Uberaba by car?
About 298 miles (480 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Uberaba to Assis drive?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from Uberaba to Assis?
In order: MG-427, SP-413, SP-265, SP-425, BR-153 and SP-333. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Uberaba to Assis?
Closest to the road: Museu Ruy Menezes (museum, mile 84, 3 mi from the route); Thermas dos Laranjais (water park, mile 109, 2 mi from the route); Museu de Paleontologia de Marília (museum, mile 253, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.