Tuxtla to Zacatlán Road Trip: Distance, Time & Stops

By admin, 12 October, 2026

The Wayro route from Tuxtla to Zacatlán is 501 miles (806 km), about 8 h 28 min of driving without stops.

U.S. State Department travel advisory: Chiapas — Level 3, Reconsider Travel; Tabasco — Level 2, Exercise Increased Caution; Veracruz — Level 2, Exercise Increased Caution; Puebla — Level 2, Exercise Increased Caution; Tlaxcala — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Puebla is the Mexican state that contains Zacatlán. Check the full advisory for this state before you go.
HuatuscoOrizaba CathedralCañón del Río Blanco National ParkMuseo Nacional del TítereMuseo Casa de PiedraBasílica de Nuestra Señora de las Misericordias, ApizacoSantuario de Nuestro Padre Jesús de AquixtlaTuxtlaZacatlán
Route from Tuxtla to Zacatlán with the 7 stops listed below (blue dots).
Distance by road501 mi (806 km)
Driving time, no stops8 h 28 min
Main roads, in orderMEX-190 → MEX-187D → MEX-180 → MEX-180D → MEX-145D → MEX-150D → MEX-136 → MEX-119
Mexican states on the routeChiapas, Tabasco, Veracruz, Puebla, Tlaxcala
Toll roads (as marked in OpenStreetMap)MEX-187D, MEX-180D, MEX-145D, MEX-150D
Fuel estimate (car at 25 mpg)about 20.0 gal; actual use varies by vehicle and traffic
Stops listed below7

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Tuxtla to Zacatlán is like

MEX-145D (142 mi) and MEX-187D (121 mi) carry about 52% of the 501 miles. It runs through 5 states: Chiapas, Tabasco, Veracruz, Puebla, Tlaxcala. OpenStreetMap marks tolled sections on MEX-187D, MEX-180D and MEX-145D. Of the 7 stops listed below, 2 are within a mile of the road.

The route from Tuxtla to Zacatlán, road by road

RoadRoute miles (from–to)Length, miState
local roads0–77Chiapas
MEX-1907–169Chiapas
MEX-187D16–137121Chiapas, Tabasco, Veracruz
MEX-180137–1425Veracruz
MEX-180D142–16321Veracruz
MEX-145D163–305142Veracruz
MEX-150D305–39287Veracruz, Puebla
local roads392–43240Puebla
MEX-136432–45523Puebla, Tlaxcala
connecting roads455–4594Tlaxcala
MEX-119459–50142Tlaxcala, Puebla
  • Mile 71 of this route: Chiapas → Tabasco (state line)
  • Mile 76 of this route: Tabasco → Veracruz (state line)
  • Mile 373 of this route: Veracruz → Puebla (state line)
  • Mile 434 of this route: Puebla → Tlaxcala (state line)
  • Mile 477 of this route: Tlaxcala → Puebla (state line)

Where to stop on the way to Zacatlán

  • Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 360), Museo Nacional del Títere (mile 441)
  • Nature and outdoors: Cañón del Río Blanco National Park (mile 360)
  • Museums and history: Huatusco (mile 313), Orizaba Cathedral (mile 351), Museo Nacional del Títere (mile 441), Museo Casa de Piedra (mile 456), Basílica de Nuestra Señora de las Misericordias, Apizaco (mile 457)

Huatusco

Mile 313 · Archaeological site · 2 mi from the route · side trip; actual detour depends on access roads

Above the Atoyac River in Carrillo Puerto, Cuauhtochco has a Mexica-era temple that still keeps original surface finishes. Expect no visitor facilities, and consider hiring a local guide.

Orizaba Cathedral

Mile 351 · Cathedral · 1 mi from the route

The Cathedral of St. Michael the Archangel is the main Catholic church of Orizaba, in the state of Veracruz, and the seat of the Diocese of Orizaba.

Cañón del Río Blanco National Park

Mile 360 · National park · 0.5 mi from the route

Veracruz is home to Cañón del Río Blanco National Park, a natural area that the Mexican government has set aside for protection.

Museo Nacional del Títere

Mile 441 · Museum · 0.9 mi from the route

On the main square of Huamantla, the National Puppet Museum (Museo Nacional del Títere) fills eight galleries with puppets from Mexico and abroad, including pieces tied to the Rosete Aranda family, whose company toured Mexico for generations.

Museo Casa de Piedra

Mile 456 · Railway museum · 2 mi from the route · side trip; actual detour depends on access roads

Apizaco's old railroad station, dating from 1916, now houses the Museo Casa de Piedra. Inside, photographs and documents trace the town's history, especially its long ties to the railroads.

Basílica de Nuestra Señora de las Misericordias, Apizaco

Mile 457 · Basilica · 2 mi from the route

In the city of Apizaco, this Catholic basilica (Basílica de Nuestra Señora de la Misericordia) was begun in the third decade of the 20th century and completed in 1961.

Santuario de Nuestro Padre Jesús de Aquixtla

Mile 488 · Sanctuary · 1 mi from the route

In the Sierra Norte de Puebla, the sanctuary of Nuestro Padre Jesús in Aquixtla draws thousands of pilgrims during the year who come to give thanks for favors received.

More drives to Zacatlán

From Tuxtla to other places in Mexico

Frequently asked questions

How long is the drive from Tuxtla to Zacatlán?

About 8 h 28 min of driving without stops, over 501 miles.

How far is Zacatlán from Tuxtla by car?

About 501 miles (806 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Tuxtla to Zacatlán?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Tuxtla to Zacatlán?

The U.S. State Department rates Chiapas Level 3: Reconsider Travel; Tabasco Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

Which highways go from Tuxtla to Zacatlán?

In order: MEX-190, MEX-187D, MEX-180, MEX-180D, MEX-145D, MEX-150D, MEX-136 and MEX-119. The road-by-road table above shows the route miles for each one.

Where can you stop on the way from Tuxtla to Zacatlán?

Closest to the road: Orizaba Cathedral (cathedral, mile 351, 1 mi from the route); Cañón del Río Blanco National Park (national park, mile 360, 0.5 mi from the route); Museo Nacional del Títere (museum, mile 441, 0.9 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.