Mexico City to Zacatlán Road Trip: Route, Stops & Safety

By admin, 3 October, 2026

The Wayro route from Mexico City to Zacatlán is 105 miles (169 km), about 2 h 27 min of driving without stops.

U.S. State Department travel advisory: Mexico City — Level 2, Exercise Increased Caution; State of Mexico — Level 2, Exercise Increased Caution; Tlaxcala — Level 2, Exercise Increased Caution; Hidalgo — Level 2, Exercise Increased Caution; Puebla — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Puebla is the Mexican state that contains Zacatlán. See the full advisory for current details.
Paleontological Museum in TocuilaCerrito de Los MelonesMolino de Flores Nezahualcóyotl National ParkTepetlaoztocLos Volcanes Biosphere ReserveTecoaqueAqueduct of Padre TemblequeMuseo del Ferrocarril de ApanMexico CityZacatlán
Route from Mexico City to Zacatlán with the 8 stops listed below (blue dots).
Distance105 mi (169 km)
Driving time, no stops2 h 27 min
Main roads, in orderMEX-136D → MEX-136 → MEX-119D → MEX-119
Mexican states on the routeMexico City (Level 2), State of Mexico (Level 2), Tlaxcala (Level 2), Hidalgo (Level 2), Puebla (Level 2)
Toll roadsMEX-136D, MEX-119D
Fuel estimate (car at 25 mpg)about 4.2 gal; actual use varies by vehicle and traffic
Stops listed below8

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Mexico City to Zacatlán is like

MEX-136 (22 mi) and MEX-119D (20 mi) carry about 40% of the 105 miles. MEX-136D, MEX-119D are toll highways (cuota); MEX-136, MEX-119 are free federal roads (libre). It runs through 5 states: Mexico City, State of Mexico, Tlaxcala, Hidalgo, Puebla. Of the 8 stops listed below, 4 are within a mile of the road.

The route from Mexico City to Zacatlán, road by road

RoadRoute miles (from–to)Length, miState
local roads0–66Mexico City
MEX-136D6–1711State of Mexico
connecting roads17–192State of Mexico
MEX-13619–4122State of Mexico, Tlaxcala
local roads41–7433Tlaxcala, Hidalgo
MEX-119D74–9420Tlaxcala, Puebla
connecting roads94–973Puebla
MEX-11997–1058Puebla
  • Mile 6 of this route: Mexico City → State of Mexico (state line)
  • Mile 32 of this route: State of Mexico → Tlaxcala (state line)
  • Mile 43 of this route: Tlaxcala → Hidalgo (state line)
  • Mile 63 of this route: Hidalgo → Tlaxcala (state line)
  • Mile 81 of this route: Tlaxcala → Puebla (state line)

Stops between Mexico City and Zacatlán

  • Right off the route (under 1 mile): Cerrito de Los Melones (mile 19), Los Volcanes Biosphere Reserve (mile 35), Tecoaque (mile 37), Museo del Ferrocarril de Apan (mile 52)
  • Nature and outdoors: Molino de Flores Nezahualcóyotl National Park (mile 21), Los Volcanes Biosphere Reserve (mile 35)
  • Museums and history: Paleontological Museum in Tocuila (mile 17), Cerrito de Los Melones (mile 19), Tepetlaoztoc (mile 24), Tecoaque (mile 37), Museo del Ferrocarril de Apan (mile 52)

Paleontological Museum in Tocuila

Mile 17 · Paleontological museum · 1 mi from the route

The Paleontological Museum in Tocuila, in Texcoco, State of Mexico, is a fossil museum displaying part of a rich deposit of Late Pleistocene animals from the Americas.

Cerrito de Los Melones

Mile 19 · Archaeological site · 0.6 mi from the route

Named for the place where it sits, Cerrito de los Melones, the Ahuehuetitlán archaeological zone of ruler Nezahualcóyotl's palace is one of the few explored traces of the great pre-Hispanic city of Acolhuacan.

Molino de Flores Nezahualcóyotl National Park

Mile 21 · National Park of Mexico · 1 mi from the route

Named for Antonio Flores de Valdés, who inherited the estate in 1642, this former hacienda and mill near Texcoco became a national park in 1937. Visitors walk among its ruins, the San Joaquín church remains and a chapel built on rock.

Tepetlaoztoc

Mile 24 · Archaeological site · 2 mi from the route

Tepetlaoztoc, also spelled Tepetlaoxtoc, was an Aztec-Nahua settlement of the Late Postclassic period in central Mexico, and it stayed occupied into the colonial era.

Los Volcanes Biosphere Reserve

Mile 35 · Biosphere reserve · 0.6 mi from the route

Surrounding the volcanoes Popocatépetl and Iztaccíhuatl, Los Volcanes is a UNESCO biosphere reserve in the Trans-Mexican Volcanic Belt, where North American and tropical wildlife zones meet.

Tecoaque

Mile 37 · Archaeological site · 0.1 mi from the route

Near Calpulalpan in western Tlaxcala, Tecoaque is a Mesoamerican archaeological site once inhabited by the Acolhua, one of the three groups that made up the Aztec Empire.

Aqueduct of Padre Tembleque

Mile 50 · Aqueduct · 15 mi from the route · side trip; actual detour depends on access roads

Built by Franciscan friar Francisco de Tembleque between 1554 and 1572, this 16th-century water system runs more than 48 km between Zempoala and Otumba. Its tallest arcade at Tepeyahualco reaches almost 40 meters, and UNESCO listed it in 2015.

Museo del Ferrocarril de Apan

Mile 52 · Museum · 0.2 mi from the route

Set in Apan's old train station on the former Mexico City–Veracruz line, this railroad museum preserves the town's history.

More drives to Zacatlán

From Mexico City to other places in Mexico

Frequently asked questions

How long is the drive from Mexico City to Zacatlán?

About 2 h 27 min of driving without stops, over 105 miles.

How far is Zacatlán from Mexico City by car?

About 105 miles (169 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Mexico City to Zacatlán?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Mexico City to Zacatlán?

The U.S. State Department rates Mexico City Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Mexico City to Zacatlán use?

In order: MEX-136D, MEX-136, MEX-119D and MEX-119. The road-by-road table above shows the route miles and states for each one.

What are good stops between Mexico City and Zacatlán?

Closest to the road: Cerrito de Los Melones (archaeological site, mile 19, 0.6 mi from the route); Tecoaque (archaeological site, mile 37, 0.1 mi from the route); Museo del Ferrocarril de Apan (museum, mile 52, 0.2 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.