The Wayro route from Tuxtla to Cholula is 452 miles (728 km), about 7 h 11 min of driving without stops.
| Distance | 452 mi (728 km) |
|---|---|
| Time at the wheel, no stops | 7 h 11 min |
| Main roads, in order | MEX-190 → MEX-187D → MEX-180 → MEX-180D → MEX-145D → MEX-150D |
| Mexican states on the route | Chiapas, Tabasco, Veracruz, Puebla |
| Toll roads (as marked in OpenStreetMap) | MEX-187D, MEX-180D, MEX-145D, MEX-150D |
| Fuel estimate (car at 25 mpg) | about 18.1 gal; actual use varies by vehicle and traffic |
| Stops listed below | 5 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
Driving Tuxtla to Cholula: the shape of the trip
MEX-145D (142 mi) and MEX-150D (137 mi) carry about 62% of the 452 miles. It runs through 4 states: Chiapas, Tabasco, Veracruz, Puebla. OpenStreetMap marks tolled sections on MEX-187D, MEX-180D and MEX-145D. Of the 5 stops listed below, 1 are within a mile of the road.
The route from Tuxtla to Cholula, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–7 | 7 | Chiapas |
| MEX-190 | 7–16 | 9 | Chiapas |
| MEX-187D | 16–137 | 121 | Chiapas, Tabasco, Veracruz |
| MEX-180 | 137–142 | 5 | Veracruz |
| MEX-180D | 142–163 | 21 | Veracruz |
| MEX-145D | 163–305 | 142 | Veracruz |
| MEX-150D | 305–442 | 137 | Veracruz, Puebla |
| local roads | 442–452 | 10 | Puebla |
- Mile 71 of this route: Chiapas → Tabasco (state line)
- Mile 76 of this route: Tabasco → Veracruz (state line)
- Mile 373 of this route: Veracruz → Puebla (state line)
Places worth a stop between Tuxtla and Cholula
- Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 360)
- Nature and outdoors: Cañón del Río Blanco National Park (mile 360), La Malinche National Park (mile 435)
- Museums and history: Cathedral of Córdoba, Veracruz (mile 339), Orizaba Cathedral (mile 352), Fort Guadalupe (mile 442)
Cathedral of Córdoba, Veracruz
An octagonal dome covered in tiles crowns Córdoba's Immaculate Conception Cathedral, the city's main church, finished in a neoclassical style.
Orizaba Cathedral
The Cathedral of St. Michael the Archangel is the main Catholic church of Orizaba, in the state of Veracruz, and the seat of the Diocese of Orizaba.
Cañón del Río Blanco National Park
Protected as a national park by Mexico's government, Cañón del Río Blanco is a natural area in Veracruz state.
La Malinche National Park
Hiking trails, birdwatching, and stone cabins and campsites at the Malintzi Vacation Center draw visitors to La Malinche National Park in Tlaxcala.
Fort Guadalupe
Fort Guadalupe is a fort you'll find in the city of Puebla, within the Mexican state of the same name.
Once you reach Cholula
San Gabriel Franciscan Convent, Cholula
The San Gabriel Franciscan Convent, also called San Gabriel Friary, is a church and friary in Cholula, part of the Puebla metropolitan area.
Museo de Historia y Antropología de Cholula
Run by INAH, the Museo de Historia y Antropología de Cholula is the site museum for Cholula's archaeological zone. Don't confuse it with the Museo Regional de Cholula, two blocks away.
Great Pyramid of Cholula
Under a hilltop church dedicated to the Virgin of los Remedios lies Tlachihualtepetl, a pyramid built in superimposed stages with a base about 400 meters per side. Excavations have opened roughly 8 km of tunnels inside the mound.
More drives to Cholula
- Mexico City to Cholula
- Toluca to Cholula
- San Juan del Río to Cholula
- Salamanca to Cholula
- Morelia to Cholula
- León to Cholula
From Tuxtla to other places in Mexico
- Tuxtla to Tapijulapa
- Tuxtla to Teapa
- Tuxtla to Chiautempan
- Tuxtla to Huejotzingo
- Tuxtla to Tlaxcala
- Tuxtla to Calpulalpan
Continue Your Adventure
Frequently asked questions
How long does it take to drive from Tuxtla to Cholula?
About 7 h 11 min of driving without stops, over 452 miles.
How far is Cholula from Tuxtla by car?
About 452 miles (728 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Tuxtla to Cholula?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Tuxtla to Cholula?
The U.S. State Department rates Chiapas Level 3: Reconsider Travel; Tabasco Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Tuxtla to Cholula use?
In order: MEX-190, MEX-187D, MEX-180, MEX-180D, MEX-145D and MEX-150D. The road-by-road table above shows the route miles for each one.
What are good stops between Tuxtla and Cholula?
Closest to the road: Cathedral of Córdoba, Veracruz (cathedral, mile 339, 2 mi from the route); Orizaba Cathedral (cathedral, mile 352, 1 mi from the route); Cañón del Río Blanco National Park (national park, mile 360, 0.5 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.