The Wayro route from Tuxtla to Tlaxcala is 463 miles (745 km), about 7 h 18 min of driving without stops.
| Distance | 463 mi (745 km) |
|---|---|
| Drive time without stops | 7 h 18 min |
| Main roads, in order | MEX-190 → MEX-187D → MEX-180 → MEX-180D → MEX-145D → MEX-150D → MEX-119D |
| Mexican states on the route | Chiapas, Tabasco, Veracruz, Puebla, Tlaxcala |
| Toll roads (as marked in OpenStreetMap) | MEX-187D, MEX-180D, MEX-145D, MEX-150D |
| Fuel estimate (car at 25 mpg) | about 18.5 gal; actual use varies by vehicle and traffic |
| Stops listed below | 7 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Tuxtla to Tlaxcala is like
MEX-150D (144 mi) and MEX-145D (142 mi) carry about 62% of the 463 miles. It runs through 5 states: Chiapas, Tabasco, Veracruz, Puebla, Tlaxcala. OpenStreetMap marks tolled sections on MEX-187D, MEX-180D and MEX-145D. Of the 7 stops listed below, 2 are within a mile of the road.
Which roads connect Tuxtla and Tlaxcala
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–7 | 7 | Chiapas |
| MEX-190 | 7–16 | 9 | Chiapas |
| MEX-187D | 16–137 | 121 | Chiapas, Tabasco, Veracruz |
| MEX-180 | 137–142 | 5 | Veracruz |
| MEX-180D | 142–163 | 21 | Veracruz |
| MEX-145D | 163–305 | 142 | Veracruz |
| MEX-150D | 305–449 | 144 | Veracruz, Puebla |
| MEX-119D | 449–460 | 11 | Puebla, Tlaxcala |
| local roads | 460–463 | 3 | Tlaxcala |
- Mile 71 of this route: Chiapas → Tabasco (state line)
- Mile 76 of this route: Tabasco → Veracruz (state line)
- Mile 373 of this route: Veracruz → Puebla (state line)
- Mile 452 of this route: Puebla → Tlaxcala (state line)
Stops between Tuxtla and Tlaxcala
- Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 360), Parque ecológico Los Ladrillos (mile 454)
- Nature and outdoors: Cañón del Río Blanco National Park (mile 360), La Malinche National Park (mile 435), Parque ecológico Los Ladrillos (mile 454)
- Museums and history: Cathedral of Córdoba, Veracruz (mile 339), Orizaba Cathedral (mile 352), Casa del Mendrugo (mile 442)
Cathedral of Córdoba, Veracruz
An octagonal dome covered in tiles crowns Córdoba's Immaculate Conception Cathedral, the city's main church, finished in a neoclassical style.
Orizaba Cathedral
The Cathedral of St. Michael the Archangel is the main Catholic church of Orizaba, in the state of Veracruz, and the seat of the Diocese of Orizaba.
Cañón del Río Blanco National Park
Cañón del Río Blanco National Park is a protected natural area in the Mexican state of Veracruz, set aside by the government as a national park.
La Malinche National Park
Hiking trails, birdwatching, and stone cabins and campsites at the Malintzi Vacation Center draw visitors to La Malinche National Park in Tlaxcala.
Casa del Mendrugo
Dating back to the early years of Puebla, founded in 1531, the Casa del Mendrugo is a historic house at 4 Sur 304 in the city's historic center.
Convento de Huejotzingo
Founded by Franciscans in the 16th century, the former convent of San Miguel Arcángel in Huejotzingo shows colonial Plateresque architecture on the western slopes of Popocatépetl and Iztaccíhuatl. UNESCO declared it a World Heritage Site in 1994.
Parque ecológico Los Ladrillos
Opened on April 2, 2015, Los Ladrillos Ecological Park is a nature reserve in the municipality of Zacatelco, in Tlaxcala.
Once you reach Tlaxcala
Exconvento de Nuestra Señora de las Nieves
The remains of this 16th-century convent stand in San Juan Totolac, Tlaxcala, and are open to visitors. Parts of the nave, two side chapels and a freestanding bell tower survive; in 1591 Tlaxcalan families left here to settle northern New Spain.
Museo Miguel N. Lira
Downtown Tlaxcala's Museo Miguel N. Lira fills the old State Printing Office, linked to the writer and poet. Visitors see his manuscripts, family photos and personal belongings, plus the original linotype machines and the press that printed his work.
Museo Nacional de Antropología e Historia de Tlaxcala
Set in the cloisters of Tlaxcala's former Franciscan convent, founded in 1528, the regional museum (Museo Regional de Tlaxcala) traces the state from paleontology and pre-Hispanic cultures through the colonial era to the Revolution, with pottery, sculpture and paintings.
More drives to Tlaxcala
- Cuautla to Tlaxcala
- Toluca to Tlaxcala
- Cuernavaca to Tlaxcala
- San Juan del Río to Tlaxcala
- Zitácuaro to Tlaxcala
- San Miguel de Allende to Tlaxcala
From Tuxtla to other places in Mexico
- Tuxtla to Tapijulapa
- Tuxtla to Teapa
- Tuxtla to Cholula
- Tuxtla to Chiautempan
- Tuxtla to Huejotzingo
- Tuxtla to Calpulalpan
Frequently asked questions
How long does it take to drive from Tuxtla to Tlaxcala?
About 7 h 18 min of driving without stops, over 463 miles.
How far is Tlaxcala from Tuxtla by car?
About 463 miles (745 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Tuxtla to Tlaxcala?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Tuxtla to Tlaxcala?
The U.S. State Department rates Chiapas Level 3: Reconsider Travel; Tabasco Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Tuxtla to Tlaxcala use?
In order: MEX-190, MEX-187D, MEX-180, MEX-180D, MEX-145D, MEX-150D and MEX-119D. The road-by-road table above shows the route miles for each one.
What are good stops between Tuxtla and Tlaxcala?
Closest to the road: Orizaba Cathedral (cathedral, mile 352, 1 mi from the route); Cañón del Río Blanco National Park (national park, mile 360, 0.5 mi from the route); Parque ecológico Los Ladrillos (park, mile 454, 0.5 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.