Melo to Piriápolis: 208 miles (335 km), about 4 h 56 min of driving. The route, U.S. travel advisory for Uruguay and 5 stops on the way.

Melo to La Paloma: 193 miles (310 km), about 5 h 10 min of driving. The route, U.S. travel advisory for Uruguay and 4 stops on the way.

Plan the Melo to Barra de Valizas road trip: 190 miles (305 km), 5 h 11 min of driving, 3 stops along the way and what the U.S. advisory says about Uruguay.

Melo to Minas: 172 miles (277 km), about 3 h 48 min of driving. The route, U.S. travel advisory for Uruguay and 3 stops on the way.

Melo to Punta del Diablo: 171 miles (275 km), about 4 h 51 min of driving. The route, U.S. travel advisory for Uruguay and 3 stops on the way.

Driving from Fray Bentos to Treinta y Tres: 355 miles, roughly 7 h 43 min without stops. Road by road, 9 places to stop and the State Department advisory.

4 stops between Salto and Treinta y Tres, plus the route: 331 miles (533 km), about 8 h 52 min of driving and the U.S. travel advisory level.

Driving from Treinta y Tres to Conchillas: 306 miles, roughly 6 h 50 min without stops. Road by road, 8 places to stop and the State Department advisory.

Colonia del Sacramento to Treinta y Tres: 286 miles (460 km), about 6 h 8 min of driving. The route, U.S. travel advisory for Uruguay and 8 stops on the way.

Treinta y Tres to Trinidad, Uruguay: 273 miles (439 km), about 5 h 43 min of driving. The route, U.S. travel advisory for Uruguay and 8 stops on the way.