Florida, Uruguay to Colonia del Sacramento Road Trip

By admin, 13 October, 2026

Florida, Uruguay to Colonia del Sacramento is about 125 road miles (201 km): roughly 2 h 44 min at the wheel if you don't stop.

U.S. State Department travel advisory: Uruguay — Level 2, Exercise Increased Caution

Full advisory: Uruguay. Advisory issued: Uruguay July 28, 2026; checked October 10, 2026.

On the roads, the State Department says:

  • Uruguay: “Traffic fatalities are high in Uruguay.”
Teatro MaccióMuseo Departamental de San JoséMuseum of Rosario Mural ArtFloridaColonia del Sacramento
Route from Florida to Colonia del Sacramento with the 3 stops listed below (blue dots).
Distance125 mi (201 km)
Drive time without stops2 h 44 min
Departments on the routeFlorida, Canelones, San José, Colonia
Fuel estimate (car at 25 mpg)about 5.0 gal; actual use varies by vehicle and traffic
Stops listed below3

The Florida–Colonia del Sacramento drive in a few lines

It runs through 4 departments: Florida, Canelones, San José, Colonia. Of the 3 stops listed below, 2 are within a mile of the road.

Road-by-road breakdown: Florida to Colonia del Sacramento

RoadRoute miles (from–to)Length, miDepartment
local roads0–5454Florida, Canelones, San José
connecting roads54–573San José
local roads57–7821San José
connecting roads78–791San José
local roads79–12546San José, Colonia
  • Mile 21 of this route: Florida → Canelones (department line)
  • Mile 33 of this route: Canelones → San José (department line)
  • Mile 81 of this route: San José → Colonia (department line)

What to see on the way from Florida to Colonia del Sacramento

  • Right off the route (under 1 mile): Teatro Macció (mile 57), Museo Departamental de San José (mile 57)
  • Museums and history: Museo Departamental de San José (mile 57), Museum of Rosario Mural Art (mile 95)

Teatro Macció

Mile 57 · Theater · 0.8 mi from the route

San José de Mayo's Teatro Bartolomé Macció is a traditional theater, regarded as the city's most important building architecturally and declared a Historic Monument of Uruguay in 1984.

Museo Departamental de San José

Mile 57 · History museum · 0.7 mi from the route

Set in central San José de Mayo, the Museo Departamental de San José is a history and fine arts museum that also runs a library, archives and cultural programs.

Museum of Rosario Mural Art

Mile 95 · Art museum · 2 mi from the route

Rather than a building, the Museum of Rosario Mural Art is a circuit of history-themed murals spread around Rosario, in Uruguay's Colonia department.

When you get to Colonia del Sacramento

Museo Paleontológico Profesor Armando Calcaterra

Paleontological museum · in Colonia del Sacramento

In the Real de San Carlos area of Colonia del Sacramento, Museo Paleontológico Profesor Armando Calcaterra shows about 1,600 pieces, including fossil vertebrates and invertebrates and Indigenous artifacts.

Basílica del Santísimo Sacramento, Colonia del Sacramento

Basilica · in Colonia del Sacramento

In Colonia del Sacramento, Uruguay, the Basílica del Santísimo Sacramento (Basilica of the Holy Sacrament) is a Roman Catholic parish church you can stop at in town.

Museo del Origami

Museum · in Colonia del Sacramento

Set in the historic district of Colonia del Sacramento, Museo del Origami is a nonprofit museum devoted to the art of paper folding and part of Uruguay's national museum system.

More drives to Colonia del Sacramento

From Florida to other places in Uruguay

Frequently asked questions

How long does it take to drive from Florida, Uruguay to Colonia del Sacramento?

About 2 h 44 min of driving without stops, over 125 miles.

What is the driving distance from Florida, Uruguay to Colonia del Sacramento?

About 125 miles (201 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Is it safe to drive from Florida, Uruguay to Colonia del Sacramento?

The U.S. State Department rates Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.

What are good stops between Florida and Colonia del Sacramento?

Closest to the road: Museo Departamental de San José (history museum, mile 57, 0.7 mi from the route); Teatro Macció (theater, mile 57, 0.8 mi from the route); Museum of Rosario Mural Art (art museum, mile 95, 2 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.