The Wayro route from Salamanca to Cholula is 254 miles (409 km), about 4 h 5 min of driving without stops.
| Distance | 254 mi (409 km) |
|---|---|
| Driving time, no stops | 4 h 5 min |
| Main roads, in order | MEX-45D → MEX-47D → MEX-57D → MEX-M40D → MEX-150 |
| Mexican states on the route | Guanajuato (Level 3), Querétaro (Level 2), State of Mexico (Level 2), Hidalgo (Level 2), Tlaxcala (Level 2), Puebla (Level 2) |
| Toll roads | MEX-45D, MEX-47D, MEX-57D, MEX-M40D |
| Fuel estimate (car at 25 mpg) | about 10.2 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Salamanca to Cholula is like
MEX-M40D (107 mi) and MEX-47D (52 mi) carry about 63% of the 254 miles. MEX-45D, MEX-47D, MEX-57D, MEX-M40D are toll highways (cuota); MEX-150 is a free federal road (libre). It runs through 6 states: Guanajuato, Querétaro, State of Mexico, Hidalgo, Tlaxcala, Puebla. Of the 9 stops listed below, 2 are within a mile of the road.
The route from Salamanca to Cholula, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–2 | 2 | Guanajuato |
| MEX-45D | 2–39 | 37 | Guanajuato |
| MEX-47D | 39–91 | 52 | Guanajuato, Querétaro |
| MEX-57D | 91–127 | 36 | Querétaro, State of Mexico, Hidalgo |
| MEX-M40D | 127–234 | 107 | Hidalgo, State of Mexico, Tlaxcala, Puebla |
| local roads | 234–245 | 11 | Puebla |
| MEX-150 | 245–254 | 9 | Puebla |
- Mile 52 of this route: Guanajuato → Querétaro (state line)
- Mile 93 of this route: Querétaro → State of Mexico (state line)
- Mile 126 of this route: State of Mexico → Hidalgo (state line)
- Mile 156 of this route: Hidalgo → State of Mexico (state line)
- Mile 170 of this route: State of Mexico → Hidalgo (state line)
- Mile 187 of this route: Hidalgo → State of Mexico (state line)
- Mile 199 of this route: State of Mexico → Hidalgo (state line)
- Mile 207 of this route: Hidalgo → Tlaxcala (state line)
- Mile 230 of this route: Tlaxcala → Puebla (state line)
Stops between Salamanca and Cholula
- Right off the route (under 1 mile): Tula National Park (mile 139), Convento de Huejotzingo (mile 245)
- Nature and outdoors: Cerro de las Campanas (mile 50), Tula National Park (mile 139), Parque nacional Xicoténcatl (mile 229)
- Museums and history: Celaya Cathedral (mile 27), Museo Arqueológico de Apaxco (mile 155)
Celaya Cathedral
Celaya's main Catholic church, the Immaculate Conception Cathedral, occupies the space of a former chapel that was annexed to the neighboring Temple of St. Francis.
Cerro de las Campanas
Rising within Querétaro City, the Cerro de las Campanas is a hill that is protected as a Mexican national park.
Atlantean figures
Crowning the main pyramid at the Tula archaeological zone, these basalt sculptures of Toltec warriors stand more than four meters tall in what was once the Toltec capital; the nearby Wall of Snakes shows carved serpents devouring skeletons.
Tula National Park
This park protects the ruins of Tula, ancient capital of the Toltecs. Walk up to the main pyramid to stand beside the Atlantes, basalt warrior figures more than four meters tall, and look for the Coatepantli wall's reliefs of snakes devouring skeletons.
Museo Arqueológico de Apaxco
Founded in 1985, the Museo Arqueológico de Apaxco sits across from the parish church of San Francisco de Asís and beside the town hall in Apaxco, State of Mexico.
Aqueduct of Padre Tembleque
Built by Franciscan friar Francisco de Tembleque between 1554 and 1572, this 16th-century water system runs more than 48 km between Zempoala and Otumba. Its tallest arcade at Tepeyahualco reaches almost 40 meters, and UNESCO listed it in 2015.
Parque nacional Xicoténcatl
Covering roughly 600 hectares in central Tlaxcala, Xicohténcatl National Park takes in the historic center of Tlaxcala city plus Quiahuixtlán, Ocotelulco and Tepeticpac, which correspond to three of the old Tlaxcalan lordships.
Exconvent of Santa María Magdalena
The former convent of Santa María Magdalena (Exconvento de Santa María Magdalena) is a 17th-century Baroque church built by the Dieguino friars, still in use as a Catholic temple of the Archdiocese of Puebla.
Convento de Huejotzingo
Founded by Franciscans in the 16th century, the former convent of San Miguel Arcángel in Huejotzingo shows colonial Plateresque architecture on the western slopes of Popocatépetl and Iztaccíhuatl. UNESCO declared it a World Heritage Site in 1994.
When you get to Cholula
La Constancia Mexicana
A textile factory founded in 1835 in Puebla now houses the La Constancia museum complex, with a children's museum, a puppet house, a Mexican music museum, an automobile museum and a park of miniature world monuments.
Tonantzintla Observatory
The Tonantzintla Observatory in Puebla was home to the National Astrophysical Observatory directed by Guillermo Haro. Its main instrument, a Schmidt camera, was a wide-field telescope built for photographing the sky.
Cholula
Cholula's Great Pyramid grew in successive construction phases around an adobe core. INAH repair work on its Pocito staircase after the 2017 earthquakes turned up broken pre-Hispanic braziers and a small limestone figure of the rain god Tláloc.
More drives to Cholula
- Mexico City to Cholula
- Toluca to Cholula
- San Juan del Río to Cholula
- Morelia to Cholula
- León to Cholula
- Uruapan to Cholula
From Salamanca to other places in Mexico
- Salamanca to Zamora
- Salamanca to Cotija
- Salamanca to Temacapulín
- Salamanca to Pabellón de Arteaga
- Salamanca to Pinos
- Salamanca to Pabellón de Hidalgo
Continue Your Adventure
Frequently asked questions
How long is the drive from Salamanca to Cholula?
About 4 h 5 min of driving without stops, over 254 miles.
How far is Cholula from Salamanca by car?
About 254 miles (409 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Salamanca to Cholula?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Salamanca to Cholula?
The U.S. State Department rates Guanajuato Level 3: Reconsider Travel; Querétaro Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Salamanca to Cholula use?
In order: MEX-45D, MEX-47D, MEX-57D, MEX-M40D and MEX-150. The road-by-road table above shows the route miles and states for each one.
What are good stops between Salamanca and Cholula?
Closest to the road: Tula National Park (National Park of Mexico, mile 139, 1 mi from the route); Atlantean figures (atlantean figures, mile 139, 1 mi from the route); Convento de Huejotzingo (convent, mile 245, 0.9 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.