Tepotzotlán to Comalcalco Road Trip: Route, Stops & Safety

By admin, 12 October, 2026

Plan on about 8 h 47 min of driving for the 487-mile (783 km) trip from Tepotzotlán to Comalcalco, before any stops.

U.S. State Department travel advisory: State of Mexico — Level 2, Exercise Increased Caution; Tlaxcala — Level 2, Exercise Increased Caution; Puebla — Level 2, Exercise Increased Caution; Veracruz — Level 2, Exercise Increased Caution; Tabasco — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Tabasco is the Mexican state that contains Comalcalco. See the full advisory for current details.
Los Remedios National ParkTexcoco CathedralTepetlaoztocCasa del AlfeñiqueLa Malinche National ParkCañón del Río Blanco National ParkHuatuscoLa VentaTepotzotlánComalcalco
Route from Tepotzotlán to Comalcalco with the 8 stops listed below (blue dots).
Distance487 mi (783 km)
Drive time without stops8 h 47 min
Main roads, in orderMEX-57 → MEX-142 → MEX-136 → MEX-M40D → MEX-150D → MEX-145D → MEX-180D → MEX-180 → MEX-187
Mexican states on the routeState of Mexico, Tlaxcala, Puebla, Veracruz, Tabasco
Toll roads (as marked in OpenStreetMap)MEX-M40D, MEX-150D, MEX-145D, MEX-180D
Fuel estimate (car at 25 mpg)about 19.5 gal; actual use varies by vehicle and traffic
Stops listed below8

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

Driving Tepotzotlán to Comalcalco: the shape of the trip

MEX-150D (151 mi) and MEX-180D (54 mi) carry about 42% of the 487 miles. It runs through 5 states: State of Mexico, Tlaxcala, Puebla, Veracruz, Tabasco. OpenStreetMap marks tolled sections on MEX-M40D, MEX-150D and MEX-145D. Of the 8 stops listed below, 2 are within a mile of the road.

The route from Tepotzotlán to Comalcalco, road by road

RoadRoute miles (from–to)Length, miState
local roads0–33State of Mexico
MEX-573–74State of Mexico
connecting roads7–92State of Mexico
local roads9–2213State of Mexico
MEX-14222–319State of Mexico
connecting roads31–321State of Mexico
MEX-13632–6533State of Mexico, Tlaxcala
MEX-M40D65–8318Tlaxcala, Puebla
connecting roads83–841Puebla
MEX-150D84–235151Puebla, Veracruz
local roads235–346111Veracruz
MEX-145D346–37731Veracruz
MEX-180D377–39821Veracruz
MEX-180398–41719Veracruz, Tabasco
MEX-180D417–45033Tabasco
MEX-180450–46212Tabasco
MEX-187462–48321Tabasco
local roads483–4874Tabasco
  • Mile 47 of this route: State of Mexico → Tlaxcala (state line)
  • Mile 80 of this route: Tlaxcala → Puebla (state line)
  • Mile 168 of this route: Puebla → Veracruz (state line)
  • Mile 416 of this route: Veracruz → Tabasco (state line)

Where to stop on the way to Comalcalco

  • Right off the route (under 1 mile): Texcoco Cathedral (mile 34), Cañón del Río Blanco National Park (mile 180)
  • Nature and outdoors: Los Remedios National Park (mile 9), La Malinche National Park (mile 111), Cañón del Río Blanco National Park (mile 180)
  • Museums and history: Texcoco Cathedral (mile 34), Tepetlaoztoc (mile 39), Casa del Alfeñique (mile 104), Huatusco (mile 228), La Venta (mile 418)

Los Remedios National Park

Mile 9 · National park · 11 mi from the route · side trip; actual detour depends on access roads

Los Remedios National Park, created by federal decree in 1938, covers about 400 hectares on the far western side of Naucalpan, just northwest of Mexico City.

Texcoco Cathedral

Mile 34 · Cathedral · 0.7 mi from the route

Texcoco's Cathedral of the Immaculate Conception occupies a former convent built by the Franciscans in the 16th century, one of the order's early convent complexes in the Americas.

Tepetlaoztoc

Mile 39 · Archaeological site · 2 mi from the route

Tepetlaoztoc, also spelled Tepetlaoxtoc, was an Aztec-Nahua settlement of the Late Postclassic period in central Mexico, and it stayed occupied into the colonial era.

Casa del Alfeñique

Mile 104 · Museum · 3 mi from the route · side trip; actual detour depends on access roads

Founded in 1926, the Museo Regional Casa de Alfeñique is a museum in the city of Puebla, housed in the building known as the Casa de Alfeñique.

La Malinche National Park

Mile 111 · National park · 11 mi from the route · side trip; actual detour depends on access roads

Hiking trails, birdwatching, and stone cabins and campsites at the Malintzi Vacation Center draw visitors to La Malinche National Park in Tlaxcala.

Cañón del Río Blanco National Park

Mile 180 · National park · 0.4 mi from the route

Cañón del Río Blanco National Park is a protected natural area in the Mexican state of Veracruz, set aside by the government as a national park.

Huatusco

Mile 228 · Archaeological site · 2 mi from the route · side trip; actual detour depends on access roads

Above the Atoyac River in Carrillo Puerto, Cuauhtochco has a Mexica-era temple that still keeps original surface finishes. Expect no visitor facilities, and consider hiring a local guide.

La Venta

Mile 418 · Archaeological site · 3 mi from the route · side trip; actual detour depends on access roads

Once an important Olmec city, La Venta sits in Tabasco close to Huimanguillo. Monumental sandstone sculptures found at the foot of its main pyramid are among the 200-plus pieces in the site museum.

When you get to Comalcalco

Comalcalco

Archaeological site · in Comalcalco

Next to the modern city of the same name in Tabasco, Comalcalco is an ancient Maya site that stands out as a major Maya city built with bricks instead of limestone, and the westernmost of the civilization.

More drives to Comalcalco

From Tepotzotlán to other places in Mexico

Frequently asked questions

How long is the drive from Tepotzotlán to Comalcalco?

About 8 h 47 min of driving without stops, over 487 miles.

How far is Comalcalco from Tepotzotlán by car?

About 487 miles (783 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Tepotzotlán to Comalcalco?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Tepotzotlán to Comalcalco?

The U.S. State Department rates State of Mexico Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution; Tabasco Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

Which highways go from Tepotzotlán to Comalcalco?

In order: MEX-57, MEX-142, MEX-136, MEX-M40D, MEX-150D, MEX-145D, MEX-180D, MEX-180 and MEX-187. The road-by-road table above shows the route miles for each one.

What are good stops between Tepotzotlán and Comalcalco?

Closest to the road: Texcoco Cathedral (cathedral, mile 34, 0.7 mi from the route); Tepetlaoztoc (archaeological site, mile 39, 2 mi from the route); Cañón del Río Blanco National Park (national park, mile 180, 0.4 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.