Comalcalco to Tlaxco is about 418 road miles (672 km): roughly 7 h 22 min at the wheel if you don't stop.
| Total distance | 418 mi (672 km) |
|---|---|
| Drive time without stops | 7 h 22 min |
| Main roads, in order | MEX-187 → MEX-180 → MEX-180D → MEX-145D → MEX-150D → MEX-136 → MEX-119 |
| Mexican states on the route | Tabasco, Veracruz, Puebla, Tlaxcala |
| Toll roads (as marked in OpenStreetMap) | MEX-180D, MEX-145D, MEX-150D |
| Fuel estimate (car at 25 mpg) | about 16.7 gal; actual use varies by vehicle and traffic |
| Stops listed below | 7 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
On the road from Comalcalco to Tlaxco
MEX-145D (142 mi) and MEX-150D (87 mi) carry about 55% of the 418 miles. It runs through 4 states: Tabasco, Veracruz, Puebla, Tlaxcala. OpenStreetMap marks tolled sections on MEX-180D, MEX-145D and MEX-150D. Of the 7 stops listed below, 2 are within a mile of the road.
Comalcalco to Tlaxco: the road sequence
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| MEX-187 | 0–24 | 24 | Tabasco |
| connecting roads | 24–25 | 1 | Tabasco |
| MEX-180 | 25–35 | 10 | Tabasco |
| MEX-180D | 35–68 | 33 | Tabasco |
| MEX-180 | 68–88 | 20 | Tabasco, Veracruz |
| MEX-180D | 88–109 | 21 | Veracruz |
| MEX-145D | 109–251 | 142 | Veracruz |
| MEX-150D | 251–338 | 87 | Veracruz, Puebla |
| local roads | 338–378 | 40 | Puebla |
| MEX-136 | 378–401 | 23 | Tlaxcala |
| connecting roads | 401–405 | 4 | Tlaxcala |
| MEX-119 | 405–417 | 12 | Tlaxcala |
| local roads | 417–418 | 1 | Tlaxcala |
- Mile 71 of this route: Tabasco → Veracruz (state line)
- Mile 319 of this route: Veracruz → Puebla (state line)
- Mile 378 of this route: Puebla → Tlaxcala (state line)
Places worth a stop between Comalcalco and Tlaxco
- Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 306), Museo Nacional del Títere (mile 386)
- Nature and outdoors: Cañón del Río Blanco National Park (mile 306)
- Museums and history: La Venta (mile 68), Huatusco (mile 258), Cathedral of Córdoba, Veracruz (mile 284), Orizaba Cathedral (mile 298), Museo Nacional del Títere (mile 386), Museo Casa de Piedra (mile 403)
La Venta
La Venta was an important city of the Olmec civilization, in Tabasco near Huimanguillo. Its site museum displays more than 200 artifacts, including monumental sandstone sculptures found at the foot of the main pyramid.
Huatusco
Above the Atoyac River in Carrillo Puerto, Cuauhtochco has a Mexica-era temple that still keeps original surface finishes. Expect no visitor facilities, and consider hiring a local guide.
Cathedral of Córdoba, Veracruz
An octagonal dome covered in tiles crowns Córdoba's Immaculate Conception Cathedral, the city's main church, finished in a neoclassical style.
Orizaba Cathedral
The Cathedral of St. Michael the Archangel is the main Catholic church of Orizaba, in the state of Veracruz, and the seat of the Diocese of Orizaba.
Cañón del Río Blanco National Park
Veracruz is home to Cañón del Río Blanco National Park, a natural area that the Mexican government has set aside for protection.
Museo Nacional del Títere
On the main square of Huamantla, the National Puppet Museum (Museo Nacional del Títere) fills eight galleries with puppets from Mexico and abroad, including pieces tied to the Rosete Aranda family, whose company toured Mexico for generations.
Museo Casa de Piedra
Apizaco's old railroad station, dating from 1916, now houses the Museo Casa de Piedra. Inside, photographs and documents trace the town's history, especially its long ties to the railroads.
More drives to Tlaxco
- Puebla to Tlaxco
- Cholula to Tlaxco
- Huejotzingo to Tlaxco
- Pachuca to Tlaxco
- Mexico City to Tlaxco
- Actopan to Tlaxco
From Comalcalco to other places in Mexico
- Comalcalco to Huejotzingo
- Comalcalco to Calpulalpan
- Comalcalco to Tetela del Volcán
- Comalcalco to Zacatlán
- Comalcalco to Otumba
- Comalcalco to Oaxtepec
Continue Your Adventure
Frequently asked questions
How long is the drive from Comalcalco to Tlaxco?
About 7 h 22 min of driving without stops, over 418 miles.
What is the driving distance from Comalcalco to Tlaxco?
About 418 miles (672 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Comalcalco to Tlaxco?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Comalcalco to Tlaxco?
The U.S. State Department rates Tabasco Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
Which highways go from Comalcalco to Tlaxco?
In order: MEX-187, MEX-180, MEX-180D, MEX-145D, MEX-150D, MEX-136 and MEX-119. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Comalcalco to Tlaxco?
Closest to the road: Orizaba Cathedral (cathedral, mile 298, 1 mi from the route); Cañón del Río Blanco National Park (national park, mile 306, 0.5 mi from the route); Museo Nacional del Títere (museum, mile 386, 0.9 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.