The Wayro route from Santos to Uberaba is 345 miles (556 km), about 6 h 51 min of driving without stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Use caution when walking or driving at night.”
| Distance by road | 345 mi (556 km) |
|---|---|
| Driving time, no stops | 6 h 51 min |
| Main roads, in order | SP-160 → SP-015 → SP-348 → SPA-102/330 → SP-330 → BR-050 |
| States on the route | São Paulo, Minas Gerais |
| Fuel estimate (car at 25 mpg) | about 13.8 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
Driving Santos to Uberaba: the shape of the trip
SP-330 (215 mi) and SP-348 (50 mi) carry about 77% of the 345 miles. It runs through 2 states: São Paulo, Minas Gerais. Of the 9 stops listed below, 3 are within a mile of the road.
The route from Santos to Uberaba, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–6 | 6 | São Paulo |
| SP-160 | 6–41 | 35 | São Paulo |
| local roads | 41–47 | 6 | São Paulo |
| SP-015 | 47–55 | 8 | São Paulo |
| connecting roads | 55–56 | 1 | São Paulo |
| SP-348 | 56–106 | 50 | São Paulo |
| SPA-102/330 | 106–111 | 5 | São Paulo |
| SP-330 | 111–326 | 215 | São Paulo |
| BR-050 | 326–342 | 16 | Minas Gerais |
| local roads | 342–345 | 3 | Minas Gerais |
- Mile 326 of this route: São Paulo → Minas Gerais (state line)
Breaking up the drive: stops between Santos and Uberaba
- Right off the route (under 1 mile): Museu da Lâmpada (mile 43), Basílica Nossa Senhora do Patrocínio (mile 152), Museu de Cravinhos (mile 228)
- Nature and outdoors: Albert Löfgren State Park (mile 56), Porto Ferreira State Park (mile 187)
- Museums and history: Museu da Lâmpada (mile 43), São Paulo Museum of Image and Sound (mile 48), Casa Guilherme de Almeida (mile 49), Museu Histórico e Pedagógico Municipal Doutor João da Silva Carrão (mile 126), Basílica Nossa Senhora do Patrocínio (mile 152), Museu de Cravinhos (mile 228)
Museu da Lâmpada
Opened in São Paulo on April 15, 2012, Museu da Lâmpada traces the history of lighting and the lamp back to prehistoric times, using items collected by the electrical supplier GIMAWA.
Cinemateca Brasileira
The Cinemateca Brasileira is the Brazilian institution responsible for preserving the country's audiovisual production.
São Paulo Museum of Image and Sound
Set up in 1970, the São Paulo Museum of Image and Sound is a public museum of audiovisual works, created to study and document new media overlooked by traditional museums.
Casa Guilherme de Almeida
Casa Guilherme de Almeida is a biographical and literary museum in São Paulo, founded in 1979 and run as a public museum under the São Paulo State Secretariat of Culture.
Albert Löfgren State Park
Better known as the São Paulo Forest Gardens, Albert Löfgren State Park is a state-run park in the state of São Paulo, Brazil.
Museu Histórico e Pedagógico Municipal Doutor João da Silva Carrão
Americana's municipal history museum occupies the old headquarters of the Fazenda Salto Grande, near where the Atibaia and Jaguari rivers meet to form the Piracicaba, and is run by the city's culture and tourism department.
Basílica Nossa Senhora do Patrocínio
Araras' Basílica Nossa Senhora do Patrocínio is a Catholic parish church that Pope Benedict XVI elevated to the rank of minor basilica in 2010; it belongs to the Diocese of Limeira.
Porto Ferreira State Park
Porto Ferreira State Park covers about 611 hectares in São Paulo state, where vegetation shifts from cerrado savanna to forest with jequitibá trees, and is set aside for recreation and environmental education.
Museu de Cravinhos
The Museu de Cravinhos is a natural history museum in Cravinhos, in the Ribeirão Preto region of São Paulo state. It opened on October 7, 2004.
When you get to Uberaba
Museu de Arte Sacra
Uberaba's sacred art museum occupies the Church of Santa Rita, built in 1854 and listed as national heritage in 1939. Inside are 18th- and 19th-century vestments, processional banners, religious images and furniture, plus an 1854 carved wooden Santa Rita.
More drives to Uberaba
- São Paulo to Uberaba
- Mogi das Cruzes to Uberaba
- São José dos Campos to Uberaba
- Praia Grande to Uberaba
- Rio de Janeiro to Uberaba
- Niterói to Uberaba
From Santos to other places in Brazil
- Santos to Itanhaém
- Santos to Bragança Paulista
- Santos to Itu
- Santos to Limeira
- Santos to Mogi Guaçu
- Santos to Botucatu
Frequently asked questions
How long does it take to drive from Santos to Uberaba?
About 6 h 51 min of driving without stops, over 345 miles.
How far is Uberaba from Santos by car?
About 345 miles (556 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Santos to Uberaba drive?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from Santos to Uberaba?
In order: SP-160, SP-015, SP-348, SPA-102/330, SP-330 and BR-050. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Santos to Uberaba?
Closest to the road: Museu da Lâmpada (museum, mile 43, 0.9 mi from the route); Basílica Nossa Senhora do Patrocínio (basilica, mile 152, 0.6 mi from the route); Museu de Cravinhos (museum, mile 228, 0.7 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.