Salamanca to San Andrés Tuxtla Road Trip: Route, Tolls & Stops

By admin, 3 October, 2026

The Wayro route from Salamanca to San Andrés Tuxtla is 496 miles (799 km), about 8 h 21 min of driving without stops.

U.S. State Department travel advisory: Guanajuato — Level 3, Reconsider Travel; Querétaro — Level 2, Exercise Increased Caution; State of Mexico — Level 2, Exercise Increased Caution; Hidalgo — Level 2, Exercise Increased Caution; Tlaxcala — Level 2, Exercise Increased Caution; Puebla — Level 2, Exercise Increased Caution; Veracruz — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Veracruz is the Mexican state that contains San Andrés Tuxtla. Check the full advisory for this state before you go.
Cerro de las CampanasEl Cimatario National ParkAtlantean figuresTeotihuacanCasa del MendrugoCañón del Río Blanco National ParkTeatro LlaveCathedral of Córdoba, VeracruzSalamancaSan Andrés Tuxtla
Route from Salamanca to San Andrés Tuxtla with the 8 stops listed below (blue dots).
Distance496 mi (799 km)
Driving time, no stops8 h 21 min
Main roads, in orderMEX-45D → MEX-47D → MEX-57D → MEX-M40D → MEX-150D → MEX-179
Mexican states on the routeGuanajuato (Level 3), Querétaro (Level 2), State of Mexico (Level 2), Hidalgo (Level 2), Tlaxcala (Level 2), Puebla (Level 2), Veracruz (Level 2)
Toll roadsMEX-45D, MEX-47D, MEX-57D, MEX-M40D, MEX-150D
Fuel estimate (car at 25 mpg)about 19.9 gal; actual use varies by vehicle and traffic
Stops listed below8

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Salamanca to San Andrés Tuxtla is like

MEX-150D (152 mi) and MEX-M40D (107 mi) carry about 52% of the 496 miles. MEX-45D, MEX-47D, MEX-57D, MEX-M40D, MEX-150D are toll highways (cuota); MEX-179 is a free federal road (libre). It runs through 7 states: Guanajuato, Querétaro, State of Mexico, Hidalgo, Tlaxcala, Puebla, Veracruz. Of the 8 stops listed below, 1 are within a mile of the road.

The route from Salamanca to San Andrés Tuxtla, road by road

RoadRoute miles (from–to)Length, miState
local roads0–22Guanajuato
MEX-45D2–3937Guanajuato
MEX-47D39–9152Guanajuato, Querétaro
MEX-57D91–12736Querétaro, State of Mexico, Hidalgo
MEX-M40D127–234107Hidalgo, State of Mexico, Tlaxcala, Puebla
MEX-150D234–386152Puebla, Veracruz
local roads386–46074Veracruz
MEX-179460–48222Veracruz
local roads482–49614Veracruz
  • Mile 52 of this route: Guanajuato → Querétaro (state line)
  • Mile 93 of this route: Querétaro → State of Mexico (state line)
  • Mile 126 of this route: State of Mexico → Hidalgo (state line)
  • Mile 156 of this route: Hidalgo → State of Mexico (state line)
  • Mile 170 of this route: State of Mexico → Hidalgo (state line)
  • Mile 187 of this route: Hidalgo → State of Mexico (state line)
  • Mile 199 of this route: State of Mexico → Hidalgo (state line)
  • Mile 207 of this route: Hidalgo → Tlaxcala (state line)
  • Mile 230 of this route: Tlaxcala → Puebla (state line)
  • Mile 318 of this route: Puebla → Veracruz (state line)

Stops between Salamanca and San Andrés Tuxtla

  • Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 331)
  • Nature and outdoors: Cerro de las Campanas (mile 50), El Cimatario National Park (mile 56), Cañón del Río Blanco National Park (mile 331)
  • Museums and history: Teotihuacan (mile 188), Casa del Mendrugo (mile 254), Cathedral of Córdoba, Veracruz (mile 353)

Cerro de las Campanas

Mile 50 · National Park of Mexico · 12 mi from the route · side trip; actual detour depends on access roads

Rising within Querétaro City, the Cerro de las Campanas is a hill that is protected as a Mexican national park.

El Cimatario National Park

Mile 56 · National Park of Mexico · 9 mi from the route · side trip; actual detour depends on access roads

El Cimatario National Park protects about 24 square kilometers of land just south of the city of Santiago de Querétaro.

Atlantean figures

Mile 139 · Atlantean figures · 1 mi from the route

Crowning the main pyramid at the Tula archaeological zone, these basalt sculptures of Toltec warriors stand more than four meters tall in what was once the Toltec capital; the nearby Wall of Snakes shows carved serpents devouring skeletons.

Teotihuacan

Mile 188 · Historic site · 13 mi from the route · side trip; actual detour depends on access roads

Built between the 1st and 7th centuries AD, this UNESCO-listed ancient city lines the Avenue of the Dead, where you can walk between the Pyramid of the Sun, the Pyramid of the Moon and the Temple of the Feathered Serpent.

Casa del Mendrugo

Mile 254 · Museum building · 3 mi from the route · side trip; actual detour depends on access roads

Dating back to the early years of Puebla, founded in 1531, the Casa del Mendrugo is a historic house at 4 Sur 304 in the city's historic center.

Cañón del Río Blanco National Park

Mile 331 · National Park of Mexico · 0.4 mi from the route

Cañón del Río Blanco National Park is a protected natural area in the Mexican state of Veracruz, set aside by the government as a national park.

Teatro Llave

Mile 339 · Theatre building · 1 mi from the route

In central Orizaba, the Gran Teatro Ignacio de la Llave hosts artistic and cultural performances, and its exhibition room shows temporary collections, mostly by artists from the surrounding valley.

Cathedral of Córdoba, Veracruz

Mile 353 · Cathedral · 2 mi from the route

Built in the first half of the 17th century, Córdoba's Immaculate Conception Cathedral is the city's main church; look up to see its octagonal dome covered in tiles, finished in a neoclassical style.

When you get to San Andrés Tuxtla

Eyipantla Falls

Waterfall · in San Andrés Tuxtla

In the Los Tuxtlas region of southern Veracruz, Eyipantla Falls is about 50 meters tall and 40 meters wide and is the main waterfall of the region.

More drives to San Andrés Tuxtla

From Salamanca to other places in Mexico

Frequently asked questions

How long is the drive from Salamanca to San Andrés Tuxtla?

About 8 h 21 min of driving without stops, over 496 miles.

How far is San Andrés Tuxtla from Salamanca by car?

About 496 miles (799 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Salamanca to San Andrés Tuxtla?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Salamanca to San Andrés Tuxtla?

The U.S. State Department rates Guanajuato Level 3: Reconsider Travel; Querétaro Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Salamanca to San Andrés Tuxtla use?

In order: MEX-45D, MEX-47D, MEX-57D, MEX-M40D, MEX-150D and MEX-179. The road-by-road table above shows the route miles and states for each one.

What are good stops between Salamanca and San Andrés Tuxtla?

Closest to the road: Atlantean figures (atlantean figures, mile 139, 1 mi from the route); Cañón del Río Blanco National Park (National Park of Mexico, mile 331, 0.4 mi from the route); Teatro Llave (theatre building, mile 339, 1 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.