The Wayro route from Cholula to San Andrés Tuxtla is 252 miles (405 km), about 4 h 41 min of driving without stops.
| Distance | 252 mi (405 km) |
|---|---|
| Driving time, no stops | 4 h 41 min |
| Main roads, in order | MEX-190 → MEX-150D → MEX-179 |
| Mexican states on the route | Puebla (Level 2), Veracruz (Level 2) |
| Toll roads | MEX-150D |
| Fuel estimate (car at 25 mpg) | about 10.1 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Cholula to San Andrés Tuxtla is like
MEX-150D (129 mi) and MEX-179 (21 mi) carry about 60% of the 252 miles. MEX-150D is a toll highway (cuota); MEX-190, MEX-179 are free federal roads (libre). It runs through 2 states: Puebla, Veracruz. Of the 8 stops listed below, 1 are within a mile of the road.
The route from Cholula to San Andrés Tuxtla, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | Puebla |
| MEX-190 | 1–5 | 4 | Puebla |
| connecting roads | 5–6 | 1 | Puebla |
| local roads | 6–10 | 4 | Puebla |
| connecting roads | 10–12 | 2 | Puebla |
| MEX-150D | 12–141 | 129 | Puebla, Veracruz |
| local roads | 141–216 | 75 | Veracruz |
| MEX-179 | 216–237 | 21 | Veracruz |
| local roads | 237–252 | 15 | Veracruz |
- Mile 73 of this route: Puebla → Veracruz (state line)
Stops between Cholula and San Andrés Tuxtla
- Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 86)
- Nature and outdoors: La Malinche National Park (mile 17), Cañón del Río Blanco National Park (mile 86)
- Museums and history: Casa del Deán (mile 7), Orizaba Cathedral (mile 94), Veracruz State Art Museum (mile 96), Cathedral of Córdoba, Veracruz (mile 108), Huatusco (mile 134)
Casa del Deán
Built in 1563 for Tomás de la Plaza y Goes, dean of Puebla Cathedral, the Casa del Deán is a historic house in Puebla that takes its name from his post.
Teatro de la Ciudad de Puebla
The Teatro de la Ciudad is a performance venue on the Portal Hidalgo, in the historic center of the city of Puebla.
La Malinche National Park
Tlaxcala's La Malinche National Park surrounds the inactive Matlalcuéyetl volcano, with pine, oak and fir forests on its slopes, hiking trails, birdwatching, and stone cabins and campsites at the Malintzi Vacation Center.
Cañón del Río Blanco National Park
Cañón del Río Blanco National Park is a protected natural area in the Mexican state of Veracruz, set aside by the government as a national park.
Orizaba Cathedral
The Cathedral of St. Michael the Archangel is the main Catholic church of Orizaba, in the state of Veracruz, and the seat of the Diocese of Orizaba.
Veracruz State Art Museum
Housed in Orizaba's 18th-century former Oratorio of San Felipe Neri, later a hospital and then a jail, the Veracruz State Art Museum (Museo de Arte del Estado) holds more than 700 works, including 36 by Diego Rivera.
Cathedral of Córdoba, Veracruz
Built in the first half of the 17th century, Córdoba's Immaculate Conception Cathedral is the city's main church; look up to see its octagonal dome covered in tiles, finished in a neoclassical style.
Huatusco
Above the Atoyac River in Carrillo Puerto, the ruins of Huatusco (Cuauhtochco) include a Mexica-era temple that still keeps original surface finishes. There are no visitor facilities; reaching it means crossing a suspension bridge and climbing a steep trail, ideally with a local guide.
When you get to San Andrés Tuxtla
Eyipantla Falls
In the Los Tuxtlas region of southern Veracruz, Eyipantla Falls is about 50 meters tall and 40 meters wide and is the main waterfall of the region.
More drives to San Andrés Tuxtla
- Puebla to San Andrés Tuxtla
- Mexico City to San Andrés Tuxtla
- Pachuca to San Andrés Tuxtla
- Cuernavaca to San Andrés Tuxtla
- Toluca to San Andrés Tuxtla
- San Juan del Río to San Andrés Tuxtla
From Cholula to other places in Mexico
- Cholula to Apizaco
- Cholula to Calpulalpan
- Cholula to Otumba
- Cholula to Omitlán
- Cholula to Tepotzotlán
- Cholula to Huasca de Ocampo
Continue Your Adventure
Frequently asked questions
How long is the drive from Cholula to San Andrés Tuxtla?
About 4 h 41 min of driving without stops, over 252 miles.
How far is San Andrés Tuxtla from Cholula by car?
About 252 miles (405 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Cholula to San Andrés Tuxtla?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Cholula to San Andrés Tuxtla?
The U.S. State Department rates Puebla Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Cholula to San Andrés Tuxtla use?
In order: MEX-190, MEX-150D and MEX-179. The road-by-road table above shows the route miles and states for each one.
What are good stops between Cholula and San Andrés Tuxtla?
Closest to the road: Teatro de la Ciudad de Puebla (theatre building, mile 7, 1 mi from the route); Cañón del Río Blanco National Park (National Park of Mexico, mile 86, 0.4 mi from the route); Veracruz State Art Museum (art museum, mile 96, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.