The Wayro route from Mexico City to San Andrés Tuxtla is 319 miles (513 km), about 5 h 45 min of driving without stops.
| Distance | 319 mi (513 km) |
|---|---|
| Driving time, no stops | 5 h 45 min |
| Main roads, in order | MEX-150D → MEX-179 |
| Mexican states on the route | Mexico City (Level 2), State of Mexico (Level 2), Puebla (Level 2), Veracruz (Level 2) |
| Toll roads | MEX-150D |
| Fuel estimate (car at 25 mpg) | about 12.8 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Mexico City to San Andrés Tuxtla is like
MEX-150D (197 mi) and MEX-179 (21 mi) carry about 68% of the 319 miles. MEX-150D is a toll highway (cuota); MEX-179 is a free federal road (libre). It runs through 4 states: Mexico City, State of Mexico, Puebla, Veracruz. Of the 9 stops listed below, 3 are within a mile of the road.
The route from Mexico City to San Andrés Tuxtla, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–10 | 10 | Mexico City, State of Mexico |
| connecting roads | 10–11 | 1 | State of Mexico |
| MEX-150D | 11–208 | 197 | State of Mexico, Puebla, Veracruz |
| local roads | 208–283 | 75 | Veracruz |
| MEX-179 | 283–304 | 21 | Veracruz |
| local roads | 304–319 | 15 | Veracruz |
- Mile 6 of this route: Mexico City → State of Mexico (state line)
- Mile 39 of this route: State of Mexico → Puebla (state line)
- Mile 140 of this route: Puebla → Veracruz (state line)
Stops between Mexico City and San Andrés Tuxtla
- Right off the route (under 1 mile): Jardín Botánico Medicinal De la Cruz-Badiano (mile 7), Museo Comunitario de San Miguel Teotongo (mile 11), Cañón del Río Blanco National Park (mile 153)
- Nature and outdoors: Jardín Botánico Medicinal De la Cruz-Badiano (mile 7), Cañón del Río Blanco National Park (mile 153)
- Museums and history: Museo Comunitario de San Miguel Teotongo (mile 11), Museo Nacional de los Ferrocarriles Mexicanos (mile 76), Veracruz State Art Museum (mile 163), Huatusco (mile 201)
- With kids: Iztapasauria (mile 8)
Jardín Botánico Medicinal De la Cruz-Badiano
UNAM's De la Cruz-Badiano medicinal botanical garden in Iztapalapa is one of Mexico's early gardens devoted to medicinal plants.
Iztapasauria
Opened on December 4, 2021, Iztapasauria is a dinosaur theme park inside the Deportivo Utopía Santa Cruz Meyehualco sports complex in Iztapalapa.
Museo Comunitario de San Miguel Teotongo
San Miguel Teotongo's community museum sits in the San Miguel Teotongo neighborhood of the Iztapalapa borough in Mexico City.
Museo Nacional de los Ferrocarriles Mexicanos
In Puebla's historic center, this national railway museum studies, preserves and shares Mexico's railroad heritage through exhibits on the history of the trains.
Teatro de la Ciudad de Puebla
The Teatro de la Ciudad is a performance venue on the Portal Hidalgo, in the historic center of the city of Puebla.
Cañón del Río Blanco National Park
Cañón del Río Blanco National Park is a protected natural area in the Mexican state of Veracruz, set aside by the government as a national park.
Teatro Llave
In central Orizaba, the Gran Teatro Ignacio de la Llave hosts artistic and cultural performances, and its exhibition room shows temporary collections, mostly by artists from the surrounding valley.
Veracruz State Art Museum
Housed in Orizaba's 18th-century former Oratorio of San Felipe Neri, later a hospital and then a jail, the Veracruz State Art Museum (Museo de Arte del Estado) holds more than 700 works, including 36 by Diego Rivera.
Huatusco
Above the Atoyac River in Carrillo Puerto, the ruins of Huatusco (Cuauhtochco) include a Mexica-era temple that still keeps original surface finishes. There are no visitor facilities; reaching it means crossing a suspension bridge and climbing a steep trail, ideally with a local guide.
When you get to San Andrés Tuxtla
Eyipantla Falls
In the Los Tuxtlas region of southern Veracruz, Eyipantla Falls is about 50 meters tall and 40 meters wide and is the main waterfall of the region.
More drives to San Andrés Tuxtla
- Puebla to San Andrés Tuxtla
- Cholula to San Andrés Tuxtla
- Pachuca to San Andrés Tuxtla
- Cuernavaca to San Andrés Tuxtla
- Toluca to San Andrés Tuxtla
- San Juan del Río to San Andrés Tuxtla
From Mexico City to other places in Mexico
- Mexico City to Metepec
- Mexico City to Toluca
- Mexico City to Cuernavaca
- Mexico City to Atlatlahucan
- Mexico City to Malinalco
- Mexico City to Cuautla
Continue Your Adventure
Frequently asked questions
How long is the drive from Mexico City to San Andrés Tuxtla?
About 5 h 45 min of driving without stops, over 319 miles.
How far is San Andrés Tuxtla from Mexico City by car?
About 319 miles (513 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Mexico City to San Andrés Tuxtla?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Mexico City to San Andrés Tuxtla?
The U.S. State Department rates Mexico City Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Mexico City to San Andrés Tuxtla use?
In order: MEX-150D and MEX-179. The road-by-road table above shows the route miles and states for each one.
What are good stops between Mexico City and San Andrés Tuxtla?
Closest to the road: Jardín Botánico Medicinal De la Cruz-Badiano (botanical garden, mile 7, 0.7 mi from the route); Museo Comunitario de San Miguel Teotongo (museum, mile 11, 0.4 mi from the route); Cañón del Río Blanco National Park (National Park of Mexico, mile 153, 0.5 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.