Plan on about 8 h 48 min of driving for the 368-mile (593 km) trip from Rosario, Argentina to Artigas, Uruguay, before any stops. You cross from Argentina into Uruguay at about mile 236, at Concordia–Salto.
Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Argentina: “Drivers should prepare in advance when taking long road trips and make sure to have adequate insurance coverage.”
- Uruguay: “Illumination, pavement markings, and road surfaces for secondary roads can be poor.”
| Total distance | 368 mi (593 km) |
|---|---|
| Time at the wheel, no stops | 8 h 48 min |
| Main roads, in order | RN174 → RP26 → RN12 → RP6 → RN18 → RN14 → RNA015 |
| Border crossing | about mile 236, Argentina → Uruguay (Concordia–Salto) |
| Regions on the route | Santa Fe, Entre Ríos, Salto, Artigas |
| Fuel estimate (car at 25 mpg) | about 14.7 gal; actual use varies by vehicle and traffic |
| Stops listed below | 3 |
Getting across the Argentina–Uruguay border
The route crosses at about mile 236, at Concordia–Salto, from Entre Ríos into Salto. Plan on two checks on each side: immigration for your passport and customs for the car.
| Entering Uruguay (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. |
|---|---|
| Driving in Uruguay | You can drive on your U.S. license. |
| Entering Argentina (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. |
| Driving in Argentina | A valid U.S. license usually works; an International Driving Permit is recommended. |
| Rental car | Cross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book. |
Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.
Driving Rosario to Artigas: the shape of the trip
RN18 (53 mi) and RP6 (39 mi) carry about 25% of the 368 miles. The first 236 miles are in Argentina; the last 132 are in Uruguay. It runs through 4 regions: Santa Fe, Entre Ríos, Salto, Artigas. Of the 3 stops listed below, 3 are within a mile of the road.
Rosario to Artigas: the road sequence
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–7 | 7 | Santa Fe |
| connecting roads | 7–8 | 1 | Santa Fe |
| RN174 | 8–46 | 38 | Santa Fe, Entre Ríos |
| connecting roads | 46–48 | 2 | Entre Ríos |
| RP26 | 48–73 | 25 | Entre Ríos |
| RN12 | 73–103 | 30 | Entre Ríos |
| RP6 | 103–142 | 39 | Entre Ríos |
| RN18 | 142–180 | 38 | Entre Ríos |
| local roads | 180–193 | 13 | Entre Ríos |
| RN18 | 193–208 | 15 | Entre Ríos |
| RN14 | 208–225 | 17 | Entre Ríos |
| connecting roads | 225–226 | 1 | Entre Ríos |
| RNA015 | 226–236 | 10 | Entre Ríos |
| local roads | 236–243 | 7 | Salto |
| connecting roads | 243–245 | 2 | Salto |
| local roads | 245–368 | 123 | Salto, Artigas |
- Mile 11 of this route: Santa Fe → Entre Ríos (region line)
- Mile 236 of this route: Entre Ríos → Salto (international border)
- Mile 315 of this route: Salto → Artigas (region line)
Places worth a stop between Rosario and Artigas
- Right off the route (under 1 mile): Abadía del Niño Dios (mile 45), Museo Nacional del Arroz (mile 186), Termas de Salto Grande (mile 237)
- Nature and outdoors: Termas de Salto Grande (mile 237)
- Museums and history: Museo Nacional del Arroz (mile 186)
Abadía del Niño Dios
Abadía del Niño Dios is a Benedictine monastery in Victoria, Entre Ríos Province. Founded in 1899, it was the first Benedictine foundation in Hispanic America.
Museo Nacional del Arroz
Opened in 2007 in San Salvador, Entre Ríos, Museo Nacional del Arroz is a rice museum housed in the former local police station, an Italianate building put up in 1929.
Termas de Salto Grande
On the Uruguayan shore of the Salto Grande dam's lake in Salto department, Termas de Salto Grande is a hot spring complex.
More drives to Artigas
- Paysandú to Artigas
- Montevideo to Artigas
- Maldonado to Artigas
- Córdoba, Argentina to Artigas, Uruguay
- La Plata to Artigas, Uruguay
- Berisso to Artigas, Uruguay
More drives from Rosario
- Rosario, Argentina to La Plata
- Rosario, Argentina to Berisso
- Rosario, Argentina to Magdalena
- Rosario, Argentina to Chascomús
- Rosario, Argentina to Cariló
- Rosario, Argentina to Villa Gesell
Continue Your Adventure
Frequently asked questions
How long is the drive from Rosario, Argentina to Artigas, Uruguay?
About 8 h 48 min of driving without stops, over 368 miles.
How far is Artigas, Uruguay from Rosario, Argentina by car?
About 368 miles (593 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Rosario to Artigas drive cross the border?
At about mile 236, from Argentina into Uruguay, at Concordia–Salto.
What do U.S. citizens need to drive from Rosario into Uruguay?
No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)
Is it safe to drive from Rosario, Argentina to Artigas, Uruguay?
The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from Rosario to Artigas?
In order: RN174, RP26, RN12, RP6, RN18, RN14 and RNA015. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Rosario to Artigas?
Closest to the road: Abadía del Niño Dios (monastery, mile 45, 0.6 mi from the route); Museo Nacional del Arroz (museum, mile 186, 0.2 mi from the route); Termas de Salto Grande (hot spring, mile 237, 0.7 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.