Plan on about 5 h 20 min of driving for the 200-mile (322 km) trip from Paysandú to Artigas, before any stops.
Full advisory: Uruguay. Advisory issued: Uruguay July 28, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Uruguay: “Traffic fatalities are high in Uruguay.”
| Total distance | 200 mi (322 km) |
|---|---|
| Drive time without stops | 5 h 20 min |
| Departments on the route | Paysandú, Salto, Artigas |
| Fuel estimate (car at 25 mpg) | about 8.0 gal; actual use varies by vehicle and traffic |
| Stops listed below | 4 |
On the road from Paysandú to Artigas
It runs through 3 departments: Paysandú, Salto, Artigas. Of the 4 stops listed below, 2 are within a mile of the road.
Road-by-road breakdown: Paysandú to Artigas
| Road | Route miles (from–to) | Length, mi | Department |
|---|---|---|---|
| local roads | 0–200 | 200 | Paysandú, Salto, Artigas |
- Mile 68 of this route: Paysandú → Salto (department line)
- Mile 147 of this route: Salto → Artigas (department line)
Where to stop on the way to Artigas
- Right off the route (under 1 mile): Termas del Guaviyú (mile 41), Termas del Daymán (mile 69)
- Nature and outdoors: Termas del Guaviyú (mile 41), Termas del Daymán (mile 69)
- Museums and history: Museo del Centro Cultural Casa Horacio Quiroga (mile 73)
Termas del Guaviyú
Next to Guaviyú Creek at kilometer 432 of Route 3 in Paysandú department, Termas del Guaviyú is a hot spring complex in northwestern Uruguay.
Termas del Daymán
Termas del Daymán is a hot springs center on the banks of the Daymán River, about 10 kilometers from the city of Salto.
Museo del Centro Cultural Casa Horacio Quiroga
In Salto, the Museo del Centro Cultural Casa Horacio Quiroga (Casa Quiroga) tells the life and work of writer Horacio Quiroga inside a house that was one of his family's summer homes.
Teatro Larrañaga
Teatro Larrañaga is the main performing arts venue in the city of Salto, Uruguay.
More drives to Artigas
- Montevideo to Artigas
- Maldonado to Artigas
- Córdoba, Argentina to Artigas, Uruguay
- Rosario, Argentina to Artigas, Uruguay
- La Plata to Artigas, Uruguay
- Berisso to Artigas, Uruguay
From Paysandú to other places in Uruguay
- Paysandú to Bella Unión
- Paysandú to Carmelo
- Paysandú to Colonia del Sacramento
- Paysandú to Veinticinco de Agosto
- Paysandú to Fray Marcos
- Paysandú to Piriápolis
Frequently asked questions
How long does it take to drive from Paysandú to Artigas?
About 5 h 20 min of driving without stops, over 200 miles.
What is the driving distance from Paysandú to Artigas?
About 200 miles (322 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Paysandú to Artigas drive?
The U.S. State Department rates Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.
What are good stops between Paysandú and Artigas?
Closest to the road: Termas del Guaviyú (hot spring, mile 41, 0.5 mi from the route); Termas del Daymán (hot spring, mile 69, 0.3 mi from the route); Teatro Larrañaga (theater, mile 73, 2 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.