The Wayro route from Berisso to Artigas, Uruguay is 449 miles (723 km), about 9 h 40 min of driving without stops. You cross from Argentina into Uruguay at about mile 318, at Concordia–Salto.
Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Argentina: “Drivers in Argentina tend to be aggressive, especially in Buenos Aires, and often ignore traffic regulations.”
- Uruguay: “Traffic fatalities are high in Uruguay.”
| Distance by road | 449 mi (723 km) |
|---|---|
| Drive time without stops | 9 h 40 min |
| Main roads, in order | 114-05 → RN1 → AV1-N → RN9 → RP6 → RN12 → RN14 → RNA015 |
| Border crossing | about mile 318, Argentina → Uruguay (Concordia–Salto) |
| Regions on the route | Buenos Aires, Ciudad de Buenos Aires, Entre Ríos, Salto, Artigas |
| Fuel estimate (car at 25 mpg) | about 18.0 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
Getting across the Argentina–Uruguay border
The route crosses at about mile 318, at Concordia–Salto, from Entre Ríos into Salto. Plan on two checks on each side: immigration for your passport and customs for the car.
| Entering Uruguay (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. |
|---|---|
| Driving in Uruguay | You can drive on your U.S. license. |
| Entering Argentina (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. |
| Driving in Argentina | A valid U.S. license usually works; an International Driving Permit is recommended. |
| Rental car | Cross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book. |
Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.
What the drive from Berisso to Artigas is like
RN14 (166 mi) and RN12 (47 mi) carry about 47% of the 449 miles. The first 318 miles are in Argentina; the last 131 are in Uruguay. It runs through 5 regions: Buenos Aires, Ciudad de Buenos Aires, Entre Ríos, Salto, Artigas. Of the 8 stops listed below, 5 are within a mile of the road.
Berisso to Artigas: the road sequence
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–1 | 1 | Buenos Aires |
| 114-05 | 1–4 | 3 | Buenos Aires |
| connecting roads | 4–7 | 3 | Buenos Aires |
| RN1 | 7–37 | 30 | Buenos Aires, Ciudad de Buenos Aires |
| local roads | 37–40 | 3 | Ciudad de Buenos Aires |
| AV1-N | 40–46 | 6 | Ciudad de Buenos Aires |
| connecting roads | 46–48 | 2 | Ciudad de Buenos Aires |
| RN9 | 48–88 | 40 | Ciudad de Buenos Aires, Buenos Aires |
| RP6 | 88–93 | 5 | Buenos Aires |
| RN12 | 93–140 | 47 | Buenos Aires, Entre Ríos |
| RN14 | 140–306 | 166 | Entre Ríos |
| connecting roads | 306–307 | 1 | Entre Ríos |
| RNA015 | 307–317 | 10 | Entre Ríos |
| local roads | 317–324 | 7 | Entre Ríos, Salto |
| connecting roads | 324–326 | 2 | Salto |
| local roads | 326–449 | 123 | Salto, Artigas |
- Mile 33 of this route: Buenos Aires → Ciudad de Buenos Aires (region line)
- Mile 49 of this route: Ciudad de Buenos Aires → Buenos Aires (region line)
- Mile 110 of this route: Buenos Aires → Entre Ríos (region line)
- Mile 318 of this route: Entre Ríos → Salto (international border)
- Mile 396 of this route: Salto → Artigas (region line)
Places worth a stop between Berisso and Artigas
- Right off the route (under 1 mile): Museo Ferroviario de Tolosa (mile 7), Cathedral of the Most Holy Trinity, Buenos Aires (mile 37), Museum of Contemporary Art of Buenos Aires (mile 37), El Palmar National Park (mile 263), Termas de Salto Grande (mile 318)
- Nature and outdoors: El Palmar National Park (mile 263), Termas de Salto Grande (mile 318)
- Museums and history: Museo Ferroviario de Tolosa (mile 7), Cathedral of the Most Holy Trinity, Buenos Aires (mile 37), Museum of Contemporary Art of Buenos Aires (mile 37), Ricardo Rojas' House Museum - Research Institute (mile 41), San Isidro Cathedral (mile 52)
- With kids: The Children's Republic (mile 10)
Museo Ferroviario de Tolosa
Run by the Tolosa branch of the Ferroclub Argentino, created in 1996, the Museo Ferroviario "Ing. Pedro C. Saccaggio" is a railway museum in Tolosa.
The Children's Republic
Spread over 131 acres in La Plata, The Children's Republic is a theme park with 35 scale-model buildings.
Cathedral of the Most Holy Trinity, Buenos Aires
Facing Lezama Park in San Telmo, the Russian Orthodox Cathedral of the Most Holy Trinity is an Eastern Orthodox church in Buenos Aires.
Museum of Contemporary Art of Buenos Aires
Often called MACBA, the Museum of Contemporary Art of Buenos Aires is an art museum in the city's San Telmo neighborhood.
Ricardo Rojas' House Museum - Research Institute
Ricardo Rojas had this Buenos Aires house built in 1927 by architect Ángel Guido; today it operates as a house museum.
San Isidro Cathedral
Main church of the Diocese of San Isidro, this cathedral stands on Del Libertador Avenue opposite Plaza Mitre, in the historic quarter of San Isidro in Buenos Aires province.
El Palmar National Park
Set off National Route 14 in Entre Ríos, between Colón and Concordia, El Palmar National Park protects groves of yatay palms along with gallery forest, savanna and grassland.
Termas de Salto Grande
On the Uruguayan shore of the Salto Grande dam's lake in Salto department, Termas de Salto Grande is a hot spring complex.
More drives to Artigas
- Paysandú to Artigas
- Montevideo to Artigas
- Maldonado to Artigas
- Córdoba, Argentina to Artigas, Uruguay
- Rosario, Argentina to Artigas, Uruguay
- La Plata to Artigas, Uruguay
More drives from Berisso
- Berisso to Adrogué
- Berisso to Tigre
- Berisso to San Antonio de Areco
- Berisso to Arrecifes
- Berisso to Martínez
- Berisso to Colón, Argentina
Continue Your Adventure
Frequently asked questions
How long is the drive from Berisso to Artigas, Uruguay?
About 9 h 40 min of driving without stops, over 449 miles.
What is the driving distance from Berisso to Artigas, Uruguay?
About 449 miles (723 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Berisso to Artigas drive cross the border?
At about mile 318, from Argentina into Uruguay, at Concordia–Salto.
What do U.S. citizens need to drive from Berisso into Uruguay?
No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)
Is it safe to drive from Berisso to Artigas, Uruguay?
The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Berisso to Artigas use?
In order: 114-05, RN1, AV1-N, RN9, RP6, RN12, RN14 and RNA015. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Berisso to Artigas?
Closest to the road: Museum of Contemporary Art of Buenos Aires (contemporary art museum, mile 37, 0.2 mi from the route); Cathedral of the Most Holy Trinity, Buenos Aires (cathedral, mile 37, 0.4 mi from the route); El Palmar National Park (national park of Argentina, mile 263, 0.2 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.