The Wayro route from Quibdó to Santa Cruz de Mompós is 537 miles (865 km), about 12 h 1 min of driving without stops.
Read the full advisory before you go: Colombia. Advisory issued: Colombia March 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Colombia: “Highways may not have lights or signs showing destinations.”
| Distance | 537 mi (865 km) |
|---|---|
| Driving time, no stops | 12 h 1 min |
| Main roads, in order | 25BAN |
| Departments on the route | Chocó, Antioquia, Santander, Cesar, Magdalena, Bolívar |
| Fuel estimate (car at 25 mpg) | about 21.5 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
On the road from Quibdó to Santa Cruz de Mompós
25BAN (18 mi) carries about 3% of the 537 miles. It runs through 6 departments: Chocó, Antioquia, Santander, Cesar, Magdalena, Bolívar. Of the 8 stops listed below, 6 are within a mile of the road.
Which roads connect Quibdó and Santa Cruz de Mompós
| Road | Route miles (from–to) | Length, mi | Department |
|---|---|---|---|
| local roads | 0–99 | 99 | Chocó, Antioquia |
| connecting roads | 99–101 | 2 | Antioquia |
| 25BAN | 101–119 | 18 | Antioquia |
| local roads | 119–132 | 13 | Antioquia |
| connecting roads | 132–133 | 1 | Antioquia |
| local roads | 133–537 | 404 | Antioquia, Santander, Cesar, Magdalena, Bolívar |
- Mile 61 of this route: Chocó → Antioquia (department line)
- Mile 248 of this route: Antioquia → Santander (department line)
- Mile 372 of this route: Santander → Cesar (department line)
- Mile 484 of this route: Cesar → Magdalena (department line)
- Mile 500 of this route: Magdalena → Bolívar (department line)
- Mile 503 of this route: Bolívar → Magdalena (department line)
- Mile 519 of this route: Magdalena → Bolívar (department line)
Where to stop on the way to Santa Cruz de Mompós
- Right off the route (under 1 mile): Catedral de Nuestra Señora de las Mercedes, Caldas (mile 128), Basílica Menor Nuestra Señora del Rosario de Chiquinquirá, La Estrella (mile 132), El Castillo Museum (mile 138), Water Museum EPM (mile 140), Our Lady of the Rosary Cathedral, Girardota (mile 156), Cathedral of Our Lady of Candelaria, El Banco (mile 493)
- Nature and outdoors: Salto Chorrolato (mile 147)
- Museums and history: Catedral de Nuestra Señora de las Mercedes, Caldas (mile 128), Basílica Menor Nuestra Señora del Rosario de Chiquinquirá, La Estrella (mile 132), El Castillo Museum (mile 138), Water Museum EPM (mile 140), Museo Etnográfico Miguel Ángel Builes (mile 142), Our Lady of the Rosary Cathedral, Girardota (mile 156), Cathedral of Our Lady of Candelaria, El Banco (mile 493)
Catedral de Nuestra Señora de las Mercedes, Caldas
This Catholic cathedral in the Colombian municipality of Caldas is dedicated to Our Lady of Mercy and serves as the seat of the bishop of the Diocese of Caldas.
Basílica Menor Nuestra Señora del Rosario de Chiquinquirá, La Estrella
Part of the Archdiocese of Medellín, this Catholic minor basilica dedicated to Our Lady of the Rosary of Chiquinquirá stands in the municipality of La Estrella, Antioquia.
El Castillo Museum
In Medellín's El Poblado district, El Castillo Museum displays porcelain and glass, stained glass, antiques, paintings and sculptures in its permanent exhibitions.
Water Museum EPM
Part of Medellín's Barefoot Park, the Water Museum EPM receives about 1,000 visitors a day, most of them students.
Museo Etnográfico Miguel Ángel Builes
Founded in 1962 by the Yarumal Missionaries, this ethnographic museum in Medellín's Ferrini neighborhood focuses on the culture and daily life of Colombia's Indigenous peoples.
Salto Chorrolato
In the San Félix area of Bello, in the Aburrá Valley near Medellín, Salto Chorrolato (Chorro del Hato) is a multi-step waterfall and a symbol of the municipality.
Our Lady of the Rosary Cathedral, Girardota
Girardota Cathedral is a Neo-Romanesque church of exposed brick, designed by French architect Charles Émile Carré and built over 32 years.
Cathedral of Our Lady of Candelaria, El Banco
Dedicated to the Virgin of Candelaria, the Cathedral of Our Lady of Candelaria (Catedral de Nuestra Señora de la Candelaria) sits in the south of El Banco, near the town's river dock.
More drives to Santa Cruz de Mompós
- Cúcuta to Santa Cruz de Mompós
- Tunja to Santa Cruz de Mompós
- Sogamoso to Santa Cruz de Mompós
- Manizales to Santa Cruz de Mompós
- Armenia to Santa Cruz de Mompós
- Pereira to Santa Cruz de Mompós
From Quibdó to other places in Colombia
- Quibdó to Guatapé
- Quibdó to Zipaquirá
- Quibdó to Sogamoso
- Quibdó to Coconuco
- Quibdó to Magangué
- Quibdó to Rincón del Mar
Frequently asked questions
How long does it take to drive from Quibdó to Santa Cruz de Mompós?
About 12 h 1 min of driving without stops, over 537 miles.
What is the driving distance from Quibdó to Santa Cruz de Mompós?
About 537 miles (865 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Quibdó to Santa Cruz de Mompós drive?
The U.S. State Department rates Colombia Level 3: Reconsider Travel. Read the full advisory before you go.
What are good stops between Quibdó and Santa Cruz de Mompós?
Closest to the road: Catedral de Nuestra Señora de las Mercedes, Caldas (cathedral, mile 128, 0.2 mi from the route); Water Museum EPM (museum, mile 140, 0.3 mi from the route); Cathedral of Our Lady of Candelaria, El Banco (cathedral, mile 493, 0.6 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.