The Wayro route from Pereira to Santa Cruz de Mompós is 534 miles (860 km), about 11 h 21 min of driving without stops.
Read the full advisory before you go: Colombia. Advisory issued: Colombia March 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Colombia: “Highways may not have lights or signs showing destinations.”
| Total distance | 534 mi (860 km) |
|---|---|
| Time at the wheel, no stops | 11 h 21 min |
| Departments on the route | Risaralda, Caldas, Tolima, Cundinamarca, Boyacá, Santander, Cesar, Magdalena, Bolívar |
| Fuel estimate (car at 25 mpg) | about 21.4 gal; actual use varies by vehicle and traffic |
| Stops listed below | 6 |
The Pereira–Santa Cruz de Mompós drive in a few lines
It runs through 9 departments: Risaralda, Caldas, Tolima, Cundinamarca, Boyacá, Santander, Cesar, Magdalena, Bolívar. Of the 6 stops listed below, 4 are within a mile of the road.
Roads you'll take from Pereira to Santa Cruz de Mompós
| Road | Route miles (from–to) | Length, mi | Department |
|---|---|---|---|
| local roads | 0–534 | 534 | Risaralda, Caldas, Tolima, Cundinamarca, Boyacá, Santander, Cesar, Magdalena, Bolívar |
- Mile 15 of this route: Risaralda → Caldas (department line)
- Mile 55 of this route: Caldas → Tolima (department line)
- Mile 145 of this route: Tolima → Cundinamarca (department line)
- Mile 154 of this route: Cundinamarca → Caldas (department line)
- Mile 162 of this route: Caldas → Cundinamarca (department line)
- Mile 190 of this route: Cundinamarca → Boyacá (department line)
- Mile 232 of this route: Boyacá → Santander (department line)
- Mile 368 of this route: Santander → Cesar (department line)
- Mile 482 of this route: Cesar → Magdalena (department line)
- Mile 497 of this route: Magdalena → Bolívar (department line)
- Mile 501 of this route: Bolívar → Magdalena (department line)
- Mile 517 of this route: Magdalena → Bolívar (department line)
Breaking up the drive: stops between Pereira and Santa Cruz de Mompós
- Right off the route (under 1 mile): Cathedral Basilica of Our Lady of the Rosary, Manizales (mile 31), Jardín botánico de la Universidad de Caldas (mile 33), Catedral de Líbano, Tolima (mile 95), Cathedral of Our Lady of Candelaria, El Banco (mile 491)
- Nature and outdoors: Jardín botánico de la Universidad de Caldas (mile 33), Los Nevados National Natural Park (mile 56)
- Museums and history: Cathedral Basilica of Our Lady of the Rosary, Manizales (mile 31), Catedral de Líbano, Tolima (mile 95), Our Lady of Mount Carmel Cathedral, La Dorada (mile 168), Cathedral of Our Lady of Candelaria, El Banco (mile 491)
Cathedral Basilica of Our Lady of the Rosary, Manizales
In front of the Plaza de Bolívar in Manizales' historic center, the Cathedral Basilica of Our Lady of the Rosary rises 119 meters, the tallest cathedral in Colombia.
Jardín botánico de la Universidad de Caldas
Run by the Universidad de Caldas in Manizales, Colombia, this botanical garden doubles as an arboretum.
Los Nevados National Natural Park
In the Cordillera Central of the Colombian Andes, Los Nevados National Natural Park takes in the volcanoes Nevado del Ruiz, Nevado del Tolima and Nevado de Santa Isabel.
Catedral de Líbano, Tolima
Dedicated to Our Lady of Carmel, the Catedral de Nuestra Señora del Carmen is a Catholic church in the city of Líbano, in Colombia's Tolima department.
Our Lady of Mount Carmel Cathedral, La Dorada
Facing Simón Bolívar Park in La Dorada, Caldas, Our Lady of Mount Carmel Cathedral is the main church of the Diocese of La Dorada-Guaduas and dates to the mid-20th century.
Cathedral of Our Lady of Candelaria, El Banco
Dedicated to the Virgin of Candelaria, the Cathedral of Our Lady of Candelaria (Catedral de Nuestra Señora de la Candelaria) sits in the south of El Banco, near the town's river dock.
More drives to Santa Cruz de Mompós
- Cúcuta to Santa Cruz de Mompós
- Tunja to Santa Cruz de Mompós
- Sogamoso to Santa Cruz de Mompós
- Manizales to Santa Cruz de Mompós
- Armenia to Santa Cruz de Mompós
- Quibdó to Santa Cruz de Mompós
From Pereira to other places in Colombia
- Pereira to Guatapé
- Pereira to Girardot City
- Pereira to Zipaquirá
- Pereira to Tunja
- Pereira to Sogamoso
- Pereira to Yopal
Frequently asked questions
How long is the drive from Pereira to Santa Cruz de Mompós?
About 11 h 21 min of driving without stops, over 534 miles.
What is the driving distance from Pereira to Santa Cruz de Mompós?
About 534 miles (860 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Pereira to Santa Cruz de Mompós drive?
The U.S. State Department rates Colombia Level 3: Reconsider Travel. Read the full advisory before you go.
Where can you stop on the way from Pereira to Santa Cruz de Mompós?
Closest to the road: Cathedral Basilica of Our Lady of the Rosary, Manizales (cathedral, mile 31, 0.7 mi from the route); Catedral de Líbano, Tolima (cathedral, mile 95, 0.0 mi from the route); Cathedral of Our Lady of Candelaria, El Banco (cathedral, mile 491, 0.6 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.