Nova Serrana to Itanhaém is about 407 road miles (655 km): roughly 9 h 8 min at the wheel if you don't stop.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Road maintenance is inadequate in many areas.”
| Distance by road | 407 mi (655 km) |
|---|---|
| Driving time, no stops | 9 h 8 min |
| Main roads, in order | BR-262 → BR-494 → BR-381 → SP-160 → SP-055 |
| States on the route | Minas Gerais, São Paulo |
| Fuel estimate (car at 25 mpg) | about 16.3 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
How the Nova Serrana to Itanhaém drive plays out
BR-381 (260 mi) and BR-494 (68 mi) carry about 81% of the 407 miles. It runs through 2 states: Minas Gerais, São Paulo. None of the 9 stops below is right on the road, so plan each as a short side trip.
The route from Nova Serrana to Itanhaém, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | Minas Gerais |
| BR-262 | 1–5 | 4 | Minas Gerais |
| BR-494 | 5–73 | 68 | Minas Gerais |
| BR-381 | 73–333 | 260 | Minas Gerais, São Paulo |
| connecting roads | 333–336 | 3 | São Paulo |
| local roads | 336–345 | 9 | São Paulo |
| SP-160 | 345–376 | 31 | São Paulo |
| connecting roads | 376–377 | 1 | São Paulo |
| SP-055 | 377–406 | 29 | São Paulo |
| local roads | 406–407 | 1 | São Paulo |
- Mile 277 of this route: Minas Gerais → São Paulo (state line)
Stops between Nova Serrana and Itanhaém
- Nature and outdoors: Monumento Natural Estadual da Pedra Grande (mile 305), Praia da Tupi (mile 385)
- Museums and history: Holy Spirit Cathedral, Divinópolis (mile 25), Monumento Natural Estadual da Pedra Grande (mile 305), Museu Penitenciário Paulista (mile 336), Museum of Sacred Art of São Paulo (mile 336), Monument to the Independence of Brazil (mile 341), Discoteca Oneyda Alvarenga (mile 341), Museum of Contemporary Art, University of São Paulo (mile 345), Centro de Memória Dorina Nowill (mile 345)
Holy Spirit Cathedral, Divinópolis
The Holy Spirit Cathedral in Divinópolis, Minas Gerais, is the Roman Catholic church that serves as seat of the Diocese of Divinópolis.
Monumento Natural Estadual da Pedra Grande
Hang gliders and paragliders launch from Pedra Grande, and a trail leads to views over nearby towns. At about 1,400 meters, it's the highest point in Atibaia.
Museu Penitenciário Paulista
Opened in 2014 on the grounds of the former Carandiru prison complex, now Parque da Juventude, this São Paulo museum covers the history of the state's prison system.
Museum of Sacred Art of São Paulo
In the left wing of the Luz Monastery, founded in 1774 by Frei Galvão, the Museum of Sacred Art of São Paulo collects and displays Brazilian sacred art.
Monument to the Independence of Brazil
Made of granite and bronze, the Monument to the Independence of Brazil stands in Independence Park in São Paulo and is also known as the Ipiranga Monument or Altar of the Fatherland.
Discoteca Oneyda Alvarenga
Founded in 1935 at Mário de Andrade's initiative, the Discoteca Oneyda Alvarenga at the Centro Cultural São Paulo collects, preserves and shares recordings of Brazilian popular and folk music.
Museum of Contemporary Art, University of São Paulo
The University of São Paulo's Museum of Contemporary Art shows contemporary art at the university's main campus and in Ibirapuera Park, both in São Paulo.
Centro de Memória Dorina Nowill
Founded in 2002 in São Paulo's Vila Clementino, Centro de Memória Dorina Nowill is a museum presenting the culture of visual impairment as historical heritage.
Praia da Tupi
Praia da Tupi is a beach in Praia Grande, São Paulo state, with yellowish sand and blue water; it is one of the city's less crowded beaches and a favorite with surfers.
More drives to Itanhaém
- Cubatão to Itanhaém
- São Paulo to Itanhaém
- Jundiaí to Itanhaém
- Bragança Paulista to Itanhaém
- Itu to Itanhaém
- Campinas to Itanhaém
From Nova Serrana to other places in Brazil
- Nova Serrana to Fumaça
- Nova Serrana to Muriaé
- Nova Serrana to Itaperuna
- Nova Serrana to Barra do Piraí
- Nova Serrana to Paranapiacaba
- Nova Serrana to Trindade
Frequently asked questions
How long is the drive from Nova Serrana to Itanhaém?
About 9 h 8 min of driving without stops, over 407 miles.
How far is Itanhaém from Nova Serrana by car?
About 407 miles (655 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Nova Serrana to Itanhaém?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from Nova Serrana to Itanhaém?
In order: BR-262, BR-494, BR-381, SP-160 and SP-055. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Nova Serrana to Itanhaém?
Closest to the road: Holy Spirit Cathedral, Divinópolis (cathedral, mile 25, 2 mi from the route); Museu Penitenciário Paulista (museum, mile 336, 2 mi from the route); Monument to the Independence of Brazil (monument, mile 341, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.