The Wayro route from Nogales to Guaymas is 262 miles (421 km), about 4 h 38 min of driving without stops. The U.S.–Mexico border is at about mile 2 on this route, near the Nogales port of entry.
| Distance | 262 mi (421 km) |
|---|---|
| Driving time, no stops | 4 h 38 min |
| Main roads, in order | MEX-15 → MEX-15D |
| Border crossing | about mile 2 of this route, Arizona → Sonora (near the Nogales, AZ port of entry) |
| Mexican states on the route | Sonora (Level 3) |
| Toll roads | MEX-15D |
| Fuel estimate (car at 25 mpg) | about 10.5 gal; actual use varies by vehicle and traffic |
| Stops listed below | 0 |
Crossing into Mexico: what you need for Guaymas
| Passport | Passport book or passport card to enter Mexico by land |
|---|---|
| FMM entry permit | Required for this trip: Guaymas is well beyond the 12-mile (20 km) border zone where the permit is not needed |
| Temporary vehicle import permit (TIP) | Not needed: Guaymas is inside Sonora's free zone (west of Highway 15 as far south as Empalme, plus a strip along the border that includes Cananea). Going farther south or east of Highway 15 requires a permit |
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you cross |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito. Sonora free zone: Explore Sonora.
Crossing at Nogales
Nogales, Arizona, and Nogales, Sonora, share several crossings: DeConcini downtown is the main gateway for visitors and daily crossers, Morley Gate nearby serves pedestrians, and Mariposa on the west side handles commercial trucks. The city is also home to Arizona's only rail crossing.
What the drive from Nogales to Guaymas is like
MEX-15D (139 mi) and MEX-15 (121 mi) carry about 99% of the 262 miles. The U.S. part of the drive runs through Arizona for about 2 miles; after the border at Nogales you have about 260 miles left in Mexico. The Mexican leg uses MEX-15D, a toll highway (cuota).
The route from Nogales to Guaymas, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | Arizona |
| MEX-15 | 1–52 | 51 | Arizona, Sonora |
| MEX-15D | 52–191 | 139 | Sonora |
| MEX-15 | 191–261 | 70 | Sonora |
| local roads | 261–262 | 1 | Sonora |
- Mile 2 of this route: Arizona → Sonora (international border)
When you get to Guaymas
Guaymas is a working port on Sonora's Gulf of California coast, where the desert mountains drop straight to the sea. Its old downtown keeps a cluster of historic churches and a waterfront plaza, and the resort area of San Carlos sits just up the coast.
- Templo de San Fernando: The church of San Fernando is one of the historic landmarks of downtown Guaymas. source
- Plaza 13 de Julio: This downtown plaza is one of the public squares highlighted by Mexico's Culture Ministry among Guaymas' points of interest. source
- Templo de San José de Guaymas: The parish church of San José is another stop on a walk through the city's historic churches, along with the Sagrado Corazón church. source
More drives to Guaymas
- Gilbert, AZ to Guaymas
- Goodyear, AZ to Guaymas
- Cottonwood, AZ to Guaymas
- Clarkdale, AZ to Guaymas
- Sierra Vista, AZ to Guaymas
- Tucson, AZ to Guaymas
From Nogales to other places in Mexico
- Nogales, AZ to San Quintín
- Nogales, AZ to Nuevo Casas Grandes
- Nogales, AZ to Rosarito
- Nogales, AZ to El Fuerte
- Nogales, AZ to San Luis Río Colorado
- Nogales, AZ to Cananea
All routes to Guaymas, border crossings and permits in one place: Driving to Guaymas, Mexico from the U.S.
Continue Your Adventure
Frequently asked questions
How long is the drive from Nogales to Guaymas?
About 4 h 38 min of driving without stops, over 262 miles.
How far is Guaymas from Nogales by car?
About 262 miles (421 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Nogales to Guaymas drive cross into Mexico?
At about mile 2 of this route, from Arizona into Sonora, near the Nogales port of entry.
Do I need a permit to drive my car from Nogales to Guaymas?
No vehicle permit is needed. Guaymas is inside Sonora's free zone (west of Highway 15 as far south as Empalme, plus a strip along the border that includes Cananea). Going farther south or east of Highway 15 requires a permit. You also need Mexican auto insurance and a passport book or card. An FMM entry permit is required too.
Is it safe to drive from Nogales to Guaymas?
The U.S. State Department rates Sonora Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Nogales to Guaymas use?
In order: MEX-15 and MEX-15D. The road-by-road table above shows the route miles and states for each one.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.