Neuquén to Santa Rosa is about 329 road miles (530 km): roughly 6 h 34 min at the wheel if you don't stop.
Full advisory: Argentina. Advisory issued: Argentina July 10, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Argentina: “Drivers should prepare in advance when taking long road trips and make sure to have adequate insurance coverage.”
| Distance | 329 mi (530 km) |
|---|---|
| Drive time without stops | 6 h 34 min |
| Main roads, in order | RN22 → RP6 → RN152 → RN35 |
| Provinces on the route | Neuquén, Río Negro, La Pampa |
| Fuel estimate (car at 25 mpg) | about 13.2 gal; actual use varies by vehicle and traffic |
| Stops listed below | 5 |
Driving Neuquén to Santa Rosa: the shape of the trip
RN152 (187 mi) and RP6 (68 mi) carry about 78% of the 329 miles. It runs through 3 provinces: Neuquén, Río Negro, La Pampa. Of the 5 stops listed below, 1 are within a mile of the road.
Neuquén to Santa Rosa: the road sequence
| Road | Route miles (from–to) | Length, mi | Province |
|---|---|---|---|
| local roads | 0–7 | 7 | Neuquén, Río Negro |
| RN22 | 7–26 | 19 | Río Negro |
| RP6 | 26–94 | 68 | Río Negro |
| RN152 | 94–281 | 187 | La Pampa |
| RN35 | 281–327 | 46 | La Pampa |
| local roads | 327–329 | 2 | La Pampa |
- Mile 2 of this route: Neuquén → Río Negro (province line)
- Mile 94 of this route: Río Negro → La Pampa (province line)
Places worth a stop between Neuquén and Santa Rosa
- Right off the route (under 1 mile): Reserva natural Casa de Piedra (mile 96)
- Nature and outdoors: Museo Patagónico de Ciencias Naturales Juan Carlos Salgado (mile 27), Reserva natural Casa de Piedra (mile 96), Lihué Calel National Park (mile 189), Parque Luro (mile 308)
- Museums and history: Estación Cultural Lucinda Larrosa Museum (mile 8), Museo Patagónico de Ciencias Naturales Juan Carlos Salgado (mile 27)
Estación Cultural Lucinda Larrosa Museum
Beside provincial route 65 in General Fernández Oro, Río Negro, this museum and cultural center started as an archaeological and regional history museum and now hosts rotating art exhibitions.
Museo Patagónico de Ciencias Naturales Juan Carlos Salgado
In General Roca, Río Negro, the Museo Patagónico de Ciencias Naturales Juan Carlos Salgado is a natural sciences museum noted for its scientific contributions and heritage collections.
Reserva natural Casa de Piedra
In the Puelén department of La Pampa Province, the Casa de Piedra nature reserve is a protected natural area.
Lihué Calel National Park
In the center of La Pampa Province, Lihué Calel National Park protects mountain plains and plateaus known for their grass tussocks.
Parque Luro
Parque Luro is a provincial nature reserve in La Pampa's Toay department, 35 km south of Santa Rosa on National Route 35, declared a protected area in 1996.
In Santa Rosa itself
Provincial Museum of Natural History
Run by La Pampa's provincial Culture Secretariat, the Provincial Museum of Natural History is a public institution in the city of Santa Rosa.
More drives to Santa Rosa
From Neuquén to other places in Argentina
- Neuquén to San Antonio Oeste
- Neuquén to Balneario El Cóndor
- Neuquén to Sierra de La Ventana
- Neuquén to Puerto Madryn
- Neuquén to Rawson
- Neuquén to Necochea
Frequently asked questions
How long is the drive from Neuquén to Santa Rosa?
About 6 h 34 min of driving without stops, over 329 miles.
What is the driving distance from Neuquén to Santa Rosa?
About 329 miles (530 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Neuquén to Santa Rosa?
The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions. Read the full advisory before you go.
What roads does the drive from Neuquén to Santa Rosa use?
In order: RN22, RP6, RN152 and RN35. The road-by-road table above shows the route miles for each one.
What are good stops between Neuquén and Santa Rosa?
Closest to the road: Estación Cultural Lucinda Larrosa Museum (museum, mile 8, 2 mi from the route); Reserva natural Casa de Piedra (park, mile 96, 0.7 mi from the route); Parque Luro (park, mile 308, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.