By road, Neuquén and San Antonio Oeste are about 260 miles (418 km) apart, or roughly 5 h 25 min of driving.
Full advisory: Argentina. Advisory issued: Argentina July 10, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Argentina: “Drivers should prepare in advance when taking long road trips and make sure to have adequate insurance coverage.”
| Distance | 260 mi (418 km) |
|---|---|
| Driving time, no stops | 5 h 25 min |
| Main roads, in order | RN22 → RN250 → RP2 → RNA026 |
| Provinces on the route | Neuquén, Río Negro |
| Fuel estimate (car at 25 mpg) | about 10.4 gal; actual use varies by vehicle and traffic |
| Stops listed below | 2 |
Driving Neuquén to San Antonio Oeste: the shape of the trip
RN22 (133 mi) and RN250 (58 mi) carry about 73% of the 260 miles. It runs through 2 provinces: Neuquén, Río Negro. Of the 2 stops listed below, 1 are within a mile of the road.
The route from Neuquén to San Antonio Oeste, road by road
| Road | Route miles (from–to) | Length, mi | Province |
|---|---|---|---|
| local roads | 0–7 | 7 | Neuquén, Río Negro |
| RN22 | 7–140 | 133 | Río Negro |
| RN250 | 140–198 | 58 | Río Negro |
| RP2 | 198–255 | 57 | Río Negro |
| RNA026 | 255–260 | 5 | Río Negro |
- Mile 2 of this route: Neuquén → Río Negro (province line)
Breaking up the drive: stops between Neuquén and San Antonio Oeste
- Right off the route (under 1 mile): Museo Patagónico de Ciencias Naturales Juan Carlos Salgado (mile 28)
- Nature and outdoors: Museo Patagónico de Ciencias Naturales Juan Carlos Salgado (mile 28)
- Museums and history: Estación Cultural Lucinda Larrosa Museum (mile 8), Museo Patagónico de Ciencias Naturales Juan Carlos Salgado (mile 28)
Estación Cultural Lucinda Larrosa Museum
Beside provincial route 65 in General Fernández Oro, Río Negro, this museum and cultural center started as an archaeological and regional history museum and now hosts rotating art exhibitions.
Museo Patagónico de Ciencias Naturales Juan Carlos Salgado
In General Roca, Río Negro, the Museo Patagónico de Ciencias Naturales Juan Carlos Salgado is a natural sciences museum noted for its scientific contributions and heritage collections.
More drives to San Antonio Oeste
- Rawson to San Antonio Oeste
- Comodoro Rivadavia to San Antonio Oeste
- Osorno to San Antonio Oeste, Argentina
From Neuquén to other places in Argentina
- Neuquén to Santa Rosa
- Neuquén to Balneario El Cóndor
- Neuquén to Sierra de La Ventana
- Neuquén to Puerto Madryn
- Neuquén to Rawson
- Neuquén to Necochea
Frequently asked questions
How long is the drive from Neuquén to San Antonio Oeste?
About 5 h 25 min of driving without stops, over 260 miles.
What is the driving distance from Neuquén to San Antonio Oeste?
About 260 miles (418 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Neuquén to San Antonio Oeste drive?
The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions. Read the full advisory before you go.
Which highways go from Neuquén to San Antonio Oeste?
In order: RN22, RN250, RP2 and RNA026. The road-by-road table above shows the route miles for each one.
What are good stops between Neuquén and San Antonio Oeste?
Closest to the road: Estación Cultural Lucinda Larrosa Museum (museum, mile 8, 2 mi from the route); Museo Patagónico de Ciencias Naturales Juan Carlos Salgado (museum, mile 28, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.