Plan on about 7 h 35 min of driving for the 401-mile (645 km) trip from Guarujá to Presidente Prudente, before any stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Flooding makes some roads through the Amazon impassable for much of the year.”
| Total distance | 401 mi (645 km) |
|---|---|
| Time at the wheel, no stops | 7 h 35 min |
| Main roads, in order | SPA-248/055 → SP-160 → SP-015 → SP-280 → SP-225 → SP-327 → SP-270 |
| States on the route | São Paulo |
| Fuel estimate (car at 25 mpg) | about 16.0 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
What the drive from Guarujá to Presidente Prudente is like
SP-280 (187 mi) and SP-270 (114 mi) carry about 75% of the 401 miles. Of the 9 stops listed below, 3 are within a mile of the road.
Roads you'll take from Guarujá to Presidente Prudente
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | São Paulo |
| SPA-248/055 | 1–19 | 18 | São Paulo |
| connecting roads | 19–22 | 3 | São Paulo |
| SP-160 | 22–53 | 31 | São Paulo |
| local roads | 53–58 | 5 | São Paulo |
| SP-015 | 58–65 | 7 | São Paulo |
| SP-280 | 65–252 | 187 | São Paulo |
| connecting roads | 252–253 | 1 | São Paulo |
| SP-225 | 253–265 | 12 | São Paulo |
| SP-327 | 265–285 | 20 | São Paulo |
| SP-270 | 285–399 | 114 | São Paulo |
| local roads | 399–401 | 2 | São Paulo |
What to see on the way from Guarujá to Presidente Prudente
- Right off the route (under 1 mile): São Paulo Zoo (mile 52), Museu de Microbiologia Prof. Isaias Raw (mile 62), Monument to Ramos de Azevedo (mile 63)
- Nature and outdoors: Parque Geológico do Varvito (mile 107)
- Museums and history: Pelé Museum (mile 7), Museu Afro Brasil (mile 58), Museu da Abadia São Geraldo (mile 58), Museu de Microbiologia Prof. Isaias Raw (mile 62), Monument to Ramos de Azevedo (mile 63), Museu de Arte Primitiva de Assis (mile 326)
- With kids: São Paulo Zoo (mile 52), São Paulo Aquarium (mile 53)
Pelé Museum
Pelé Museum (Museu Pelé) in Santos is dedicated to the career of former player Pelé. It opened in June 2014 as part of the side events of the FIFA World Cup.
São Paulo Zoo
Set in São Paulo's South Zone on 824,529 square meters of former Atlantic Forest, the São Paulo Zoo contains the spring of the Ipiranga Brook and about four kilometers of pathways.
São Paulo Aquarium
The São Paulo Aquarium is an oceanarium in the Ipiranga district of São Paulo, opened in July 2006 as the first themed aquarium in Latin America.
Museu Afro Brasil
Museu Afro Brasil is a public history, art and ethnographic museum devoted to objects and works tied to Black culture in Brazil, under the São Paulo State Secretariat for Culture.
Museu da Abadia São Geraldo
Hungarian Benedictine monks from Pannonhalma Abbey founded the Museu da Abadia São Geraldo in São Paulo's Jardim Colombo to preserve the memory of their congregation in Brazil, which dates to the 1930s.
Museu de Microbiologia Prof. Isaias Raw
Opened in 2002, Museu de Microbiologia Prof. Isaias Raw is part of the Instituto Butantan complex in São Paulo and uses exhibits and educational activities to spark scientific curiosity, especially among young people.
Monument to Ramos de Azevedo
Sculptor Galileo Emendabili designed this bronze-and-granite monument in São Paulo as a tribute to architect Francisco de Paula Ramos de Azevedo.
Parque Geológico do Varvito
Glacial lakes about 280 million years ago left behind the layered varvite now visible at this closed quarry in Itu. The site is a protected geological monument, and visitors can walk right past its walls.
Museu de Arte Primitiva de Assis
Assis's museum of primitive (naïve) art, founded by José Nazareno Mimessi, sits inside Parque do Buracão, an ecological park, in its own climate-controlled building opened in 1999. It is run by the city's culture department.
In Presidente Prudente itself
Teatro Municipal Procópio Ferreira
Named after actor Procópio Ferreira, this municipal theater in Presidente Prudente, São Paulo state, is the city's most-used public venue.
More drives to Presidente Prudente
- Araraquara to Presidente Prudente
- Limeira to Presidente Prudente
- Campinas to Presidente Prudente
- Jundiaí to Presidente Prudente
- Mogi das Cruzes to Presidente Prudente
- São Vicente to Presidente Prudente
From Guarujá to other places in Brazil
- Guarujá to Paranapiacaba
- Guarujá to Bragança Paulista
- Guarujá to Itu
- Guarujá to Limeira
- Guarujá to Mogi Guaçu
- Guarujá to Botucatu
Frequently asked questions
How long is the drive from Guarujá to Presidente Prudente?
About 7 h 35 min of driving without stops, over 401 miles.
What is the driving distance from Guarujá to Presidente Prudente?
About 401 miles (645 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Guarujá to Presidente Prudente?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Guarujá to Presidente Prudente use?
In order: SPA-248/055, SP-160, SP-015, SP-280, SP-225, SP-327 and SP-270. The road-by-road table above shows the route miles for each one.
What are good stops between Guarujá and Presidente Prudente?
Closest to the road: São Paulo Zoo (zoo, mile 52, 0.8 mi from the route); Museu de Microbiologia Prof. Isaias Raw (museum, mile 62, 0.9 mi from the route); Monument to Ramos de Azevedo (monument, mile 63, 0.7 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.