The Wayro route from São Vicente to Presidente Prudente is 385 miles (619 km), about 7 h 10 min of driving without stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Drivers must have their daytime running lights on during the day and headlights on at night on Federal Highways.”
| Distance | 385 mi (619 km) |
|---|---|
| Drive time without stops | 7 h 10 min |
| Main roads, in order | SP-160 → SP-015 → SP-280 → SP-225 → SP-327 → SP-270 |
| States on the route | São Paulo |
| Fuel estimate (car at 25 mpg) | about 15.4 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
On the road from São Vicente to Presidente Prudente
SP-280 (189 mi) and SP-270 (114 mi) carry about 79% of the 385 miles. Of the 9 stops listed below, 1 are within a mile of the road.
Roads you'll take from São Vicente to Presidente Prudente
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | São Paulo |
| SP-160 | 1–37 | 36 | São Paulo |
| local roads | 37–42 | 5 | São Paulo |
| SP-015 | 42–48 | 6 | São Paulo |
| SP-280 | 48–237 | 189 | São Paulo |
| SP-225 | 237–249 | 12 | São Paulo |
| SP-327 | 249–269 | 20 | São Paulo |
| SP-270 | 269–383 | 114 | São Paulo |
| local roads | 383–385 | 2 | São Paulo |
Places worth a stop between São Vicente and Presidente Prudente
- Right off the route (under 1 mile): Museu Biológico do Instituto Butantan (mile 46)
- Nature and outdoors: Jaraguá State Park (mile 52), Parque Geológico do Varvito (mile 91)
- Museums and history: Museu Lasar Segall (mile 39), Casa de Vidro (mile 42), Galeria Luisa Strina (mile 43), Museu Biológico do Instituto Butantan (mile 46), Estação de Assis (mile 309)
- With kids: Cidade da Criança (mile 32), Simba Safari (mile 35)
Cidade da Criança
Opened on October 10, 1968, Cidade da Criança in São Bernardo do Campo was the first theme park in Brazil and Latin America and sits behind the former Vera Cruz Film Studios.
Simba Safari
At Simba Safari, a zoo in São Paulo's Cursino district, visitors ride park vehicles along a route of about 2.9 km through roughly 80,000 square meters to see the animals.
Museu Lasar Segall
Housed in the home and studio architect Gregori Warchavchik designed in 1932, the Museu Lasar Segall in São Paulo is an art museum devoted to artist Lasar Segall, who lived there until 1957.
Casa de Vidro
Architect Lina Bo Bardi designed the Casa de Vidro, built in 1950–1951 in São Paulo's Morumbi area on land that was once part of a tea farm.
Galeria Luisa Strina
Founded by art collector Luisa Malzone Strina, Galeria Luisa Strina is an art gallery with its main space and an annex in São Paulo.
Museu Biológico do Instituto Butantan
At the Instituto Butantan in São Paulo, the Museu Biológico displays live snakes, lizards, spiders, and scorpions at an institute that became autonomous in 1901 under its first director, Vital Brazil.
Jaraguá State Park
A former gold-era farm turned state park in 1961, Jaraguá State Park guards one of the last Atlantic Forest remnants in greater São Paulo, with trails around 1,135-meter Jaraguá Peak.
Parque Geológico do Varvito
Banded rock walls line a former quarry in Itu, where Parque Geológico do Varvito shows off varvite, sediment that settled in glacial lakes some 280 million years ago.
Estação de Assis
Assis's railway station joined the company's trunk line in 1914 and got its current building in 1926; the original station was adapted as housing for traffic staff in 1927.
In Presidente Prudente itself
Teatro Municipal Procópio Ferreira
Named after actor Procópio Ferreira, this municipal theater in Presidente Prudente, São Paulo state, is the city's most-used public venue.
More drives to Presidente Prudente
- Araraquara to Presidente Prudente
- Limeira to Presidente Prudente
- Campinas to Presidente Prudente
- Jundiaí to Presidente Prudente
- Mogi das Cruzes to Presidente Prudente
- Praia Grande to Presidente Prudente
From São Vicente to other places in Brazil
- São Vicente to Paranapiacaba
- São Vicente to Bragança Paulista
- São Vicente to Itu
- São Vicente to Limeira
- São Vicente to Mogi Guaçu
- São Vicente to Botucatu
Frequently asked questions
How long does it take to drive from São Vicente to Presidente Prudente?
About 7 h 10 min of driving without stops, over 385 miles.
How far is Presidente Prudente from São Vicente by car?
About 385 miles (619 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from São Vicente to Presidente Prudente?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from São Vicente to Presidente Prudente?
In order: SP-160, SP-015, SP-280, SP-225, SP-327 and SP-270. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from São Vicente to Presidente Prudente?
Closest to the road: Simba Safari (zoo, mile 35, 1 mi from the route); Museu Biológico do Instituto Butantan (museum, mile 46, 0.7 mi from the route); Estação de Assis (museum, mile 309, 2 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.