Plan on about 6 h 9 min of driving for the 324-mile (522 km) trip from Guarujá to Assis, before any stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Drivers must have their daytime running lights on during the day and headlights on at night on Federal Highways.”
| Distance by road | 324 mi (522 km) |
|---|---|
| Drive time without stops | 6 h 9 min |
| Main roads, in order | SPA-248/055 → SP-160 → SP-015 → SP-280 → SP-225 → SP-327 → SP-270 |
| States on the route | São Paulo |
| Fuel estimate (car at 25 mpg) | about 13.0 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
What the drive from Guarujá to Assis is like
SP-280 (187 mi) and SP-270 (36 mi) carry about 69% of the 324 miles. Of the 9 stops listed below, 2 are within a mile of the road.
Road-by-road breakdown: Guarujá to Assis
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | São Paulo |
| SPA-248/055 | 1–19 | 18 | São Paulo |
| connecting roads | 19–22 | 3 | São Paulo |
| SP-160 | 22–53 | 31 | São Paulo |
| local roads | 53–58 | 5 | São Paulo |
| SP-015 | 58–65 | 7 | São Paulo |
| SP-280 | 65–252 | 187 | São Paulo |
| connecting roads | 252–253 | 1 | São Paulo |
| SP-225 | 253–265 | 12 | São Paulo |
| SP-327 | 265–285 | 20 | São Paulo |
| SP-270 | 285–321 | 36 | São Paulo |
| local roads | 321–324 | 3 | São Paulo |
Breaking up the drive: stops between Guarujá and Assis
- Right off the route (under 1 mile): Museu da Lâmpada (mile 55), Monument to Ramos de Azevedo (mile 63)
- Nature and outdoors: Parque Geológico do Varvito (mile 107)
- Museums and history: Pelé Museum (mile 7), Pinacoteca de São Bernardo do Campo (mile 48), Museu da Lâmpada (mile 55), Museu Lasar Segall (mile 55), Luiz Cássio dos Santos Werneck Memorial (mile 58), Fundadores de São Paulo (mile 59), Monument to Ramos de Azevedo (mile 63)
- With kids: Simba Safari (mile 52)
Pelé Museum
Pelé Museum (Museu Pelé) in Santos is dedicated to the career of former player Pelé. It opened in June 2014 as part of the side events of the FIFA World Cup.
Pinacoteca de São Bernardo do Campo
This municipal art gallery in São Bernardo do Campo studies and shows modern and contemporary art, with works by Tomie Ohtake, Waldomiro de Deus and Wesley Duke Lee in its collection.
Simba Safari
At Simba Safari, a zoo in São Paulo's Cursino district, visitors ride park vehicles along a route of about 2.9 km through roughly 80,000 square meters to see the animals.
Museu da Lâmpada
Opened in São Paulo on April 15, 2012, Museu da Lâmpada traces the history of lighting and the lamp back to prehistoric times, using items collected by the electrical supplier GIMAWA.
Museu Lasar Segall
Housed in the home and studio architect Gregori Warchavchik designed in 1932, the Museu Lasar Segall in São Paulo is an art museum devoted to artist Lasar Segall, who lived there until 1957.
Luiz Cássio dos Santos Werneck Memorial
Opened in 1994, the Luiz Cássio dos Santos Werneck Memorial preserves the history of São Paulo Futebol Clube, displaying historic objects to fans and visitors.
Fundadores de São Paulo
In São Paulo's Vila Mariana neighborhood, Fundadores de São Paulo is a monument by sculptor Luis Morrone honoring the city's founders, inaugurated in 1963 after ten years of construction.
Monument to Ramos de Azevedo
Sculptor Galileo Emendabili designed this bronze-and-granite monument in São Paulo as a tribute to architect Francisco de Paula Ramos de Azevedo.
Parque Geológico do Varvito
In Itu, a closed quarry exposes layers of varvite, sediment laid down in glacial lakes about 280 million years ago. Parque Geológico do Varvito lets visitors walk past these banded rock walls, a protected geological monument.
When you get to Assis
Estação de Assis
Assis's railway station joined the company's trunk line in 1914 and got its current building in 1926; the original station was adapted as housing for traffic staff in 1927.
Museu de Arte Primitiva de Assis
Assis's museum of primitive (naïve) art, founded by José Nazareno Mimessi, sits inside Parque do Buracão, an ecological park, in its own climate-controlled building opened in 1999. It is run by the city's culture department.
More drives to Assis
- Jaú to Assis
- Araraquara to Assis
- Ribeirão Preto to Assis
- São Paulo to Assis
- Mogi Guaçu to Assis
- Poços de Caldas to Assis
From Guarujá to other places in Brazil
- Guarujá to Paranapiacaba
- Guarujá to Bragança Paulista
- Guarujá to Itu
- Guarujá to Limeira
- Guarujá to Mogi Guaçu
- Guarujá to Botucatu
Frequently asked questions
How long does it take to drive from Guarujá to Assis?
About 6 h 9 min of driving without stops, over 324 miles.
How far is Assis from Guarujá by car?
About 324 miles (522 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Guarujá to Assis?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from Guarujá to Assis?
In order: SPA-248/055, SP-160, SP-015, SP-280, SP-225, SP-327 and SP-270. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Guarujá to Assis?
Closest to the road: Simba Safari (zoo, mile 52, 1 mi from the route); Museu da Lâmpada (museum, mile 55, 0.9 mi from the route); Monument to Ramos de Azevedo (monument, mile 63, 0.7 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.