The Wayro route from Córdoba, Argentina to Cafayate is 437 miles (704 km), about 9 h 26 min of driving without stops.
Full advisory: Argentina. Advisory issued: Argentina July 10, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Argentina: “Drivers should prepare in advance when taking long road trips and make sure to have adequate insurance coverage.”
| Distance by road | 437 mi (704 km) |
|---|---|
| Time at the wheel, no stops | 9 h 26 min |
| Main roads, in order | RN2V9 → RN9 → RN60 → RN157 → RP325 → RN38 → RP307 → RP357 → RN40 |
| Provinces on the route | Córdoba, Catamarca, Santiago del Estero, Tucumán, Salta |
| Fuel estimate (car at 25 mpg) | about 17.5 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
Driving Córdoba to Cafayate: the shape of the trip
RN157 (162 mi) and RN60 (103 mi) carry about 61% of the 437 miles. It runs through 5 provinces: Córdoba, Catamarca, Santiago del Estero, Tucumán, Salta. Of the 8 stops listed below, 4 are within a mile of the road.
Road-by-road breakdown: Córdoba to Cafayate
| Road | Route miles (from–to) | Length, mi | Province |
|---|---|---|---|
| local roads | 0–4 | 4 | Córdoba |
| connecting roads | 4–6 | 2 | Córdoba |
| RN2V9 | 6–15 | 9 | Córdoba |
| RN9 | 15–47 | 32 | Córdoba |
| RN60 | 47–150 | 103 | Córdoba, Catamarca |
| RN157 | 150–312 | 162 | Catamarca, Santiago del Estero, Tucumán |
| RP325 | 312–322 | 10 | Tucumán |
| RN38 | 322–326 | 4 | Tucumán |
| RP307 | 326–396 | 70 | Tucumán |
| RP357 | 396–405 | 9 | Tucumán |
| RN40 | 405–437 | 32 | Tucumán, Salta |
- Mile 146 of this route: Córdoba → Catamarca (province line)
- Mile 209 of this route: Catamarca → Santiago del Estero (province line)
- Mile 221 of this route: Santiago del Estero → Catamarca (province line)
- Mile 264 of this route: Catamarca → Tucumán (province line)
- Mile 423 of this route: Tucumán → Salta (province line)
Breaking up the drive: stops between Córdoba and Cafayate
- Right off the route (under 1 mile): Estancia of Caroya (mile 32), Estancia of Jesús María (mile 34), Reserva provincial La Angostura (mile 359), Museo Pachamama (mile 396)
- Nature and outdoors: Aconquija National Park (mile 340), Reserva arqueológica Los Menhires (mile 352), Reserva provincial La Angostura (mile 359)
- Museums and history: Estancia of Jesús María (mile 34), Museo Pachamama (mile 396), Ruins of Quilmes (mile 407)
Estancia of Caroya
On the western edge of Colonia Caroya in Córdoba Province, the Estancia of Caroya (Estancia Jesuítica Caroya) was one of the rural establishments owned by the Jesuits.
Estancia of Jesús María
One of Córdoba Province's five Jesuit estancias, the Estancia of Jesús María houses the National Jesuit Museum and is part of a group declared a UNESCO World Heritage Site in 2000.
San José Charterhouse
In Deán Funes, Córdoba, San José Charterhouse is a Carthusian monastery dedicated to Saint Joseph, the third such monastery in the Americas.
Aconquija National Park
Established on August 9, 1995 in Tucumán Province, Aconquija National Park protects a representative sample of Southern Andean Yungas montane forest. It was formerly called Campo de los Alisos National Park.
Reserva arqueológica Los Menhires
Near El Mollar in Tafí del Valle, the Los Menhires archaeological reserve displays granite standing stones carved and moved by local inhabitants some 2,000 years ago, facing the La Angostura reservoir.
Reserva provincial La Angostura
Near the town of El Mollar in Tafí del Valle department, Tucumán, La Angostura is a strict provincial nature reserve.
Museo Pachamama
Museo Pachamama, in the Tucumán town of Amaicha del Valle, displays characteristic features of the Calchaquí Valleys.
Ruins of Quilmes
In the Calchaquí Valleys of Tucumán Province, the Ruins of Quilmes mark a pre-Columbian settlement that covered about 74 acres, the largest in the country.
Once you reach Cafayate
Our Lady of Rosary Cathedral, Cafayate
In the town of Cafayate, Salta Province, Our Lady of Rosary Cathedral is the seat of the Catholic bishopric of Cafayate, under the Archdiocese of Salta.
Museo de la Vid y el Vino
In Cafayate, Salta Province, the Museo de la Vid y el Vino is a museum devoted to grapevines and winemaking.
More drives to Cafayate
- San Miguel de Tucumán to Cafayate
- Tafí Viejo to Cafayate
- La Quiaca to Cafayate
- Tupiza to Cafayate, Argentina
- Uyuni to Cafayate, Argentina
From Córdoba to other places in Argentina
- Córdoba, Argentina to Paraná
- Córdoba, Argentina to Concordia
- Córdoba, Argentina to Gualeguaychú
- Córdoba, Argentina to Tigre
- Córdoba, Argentina to Adrogué
- Córdoba, Argentina to Chajarí
Frequently asked questions
How long does it take to drive from Córdoba, Argentina to Cafayate?
About 9 h 26 min of driving without stops, over 437 miles.
What is the driving distance from Córdoba, Argentina to Cafayate?
About 437 miles (704 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Córdoba, Argentina to Cafayate?
The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions. Read the full advisory before you go.
Which highways go from Córdoba to Cafayate?
In order: RN2V9, RN9, RN60, RN157, RP325, RN38, RP307, RP357 and RN40. The road-by-road table above shows the route miles for each one.
What are good stops between Córdoba and Cafayate?
Closest to the road: Estancia of Caroya (estancia, mile 32, 0.4 mi from the route); Estancia of Jesús María (history museum, mile 34, 0.9 mi from the route); Museo Pachamama (museum, mile 396, 0.1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.