Comalcalco to Zacatlán Road Trip: Route, Tolls & Stops

By admin, 12 October, 2026

Comalcalco to Zacatlán is about 447 road miles (719 km): roughly 7 h 59 min at the wheel if you don't stop.

U.S. State Department travel advisory: Tabasco — Level 2, Exercise Increased Caution; Veracruz — Level 2, Exercise Increased Caution; Puebla — Level 2, Exercise Increased Caution; Tlaxcala — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Puebla is the Mexican state that contains Zacatlán. See the full advisory for current details.
La VentaTeatro Pedro DíazOrizaba CathedralCañón del Río Blanco National ParkMuseo Nacional del TítereMuseo Casa de PiedraSantuario de Nuestro Padre Jesús de AquixtlaComalcalcoZacatlán
Route from Comalcalco to Zacatlán with the 7 stops listed below (blue dots).
Total distance447 mi (719 km)
Driving time, no stops7 h 59 min
Main roads, in orderMEX-187 → MEX-180 → MEX-180D → MEX-145D → MEX-150D → MEX-136 → MEX-119
Mexican states on the routeTabasco, Veracruz, Puebla, Tlaxcala
Toll roads (as marked in OpenStreetMap)MEX-180D, MEX-145D, MEX-150D
Fuel estimate (car at 25 mpg)about 17.9 gal; actual use varies by vehicle and traffic
Stops listed below7

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Comalcalco to Zacatlán is like

MEX-145D (142 mi) and MEX-150D (87 mi) carry about 51% of the 447 miles. It runs through 4 states: Tabasco, Veracruz, Puebla, Tlaxcala. OpenStreetMap marks tolled sections on MEX-180D, MEX-145D and MEX-150D. Of the 7 stops listed below, 2 are within a mile of the road.

Road-by-road breakdown: Comalcalco to Zacatlán

RoadRoute miles (from–to)Length, miState
MEX-1870–2424Tabasco
connecting roads24–251Tabasco
MEX-18025–3510Tabasco
MEX-180D35–6833Tabasco
MEX-18068–8820Tabasco, Veracruz
MEX-180D88–10921Veracruz
MEX-145D109–251142Veracruz
MEX-150D251–33887Veracruz, Puebla
local roads338–37840Puebla
MEX-136378–40123Tlaxcala
connecting roads401–4054Tlaxcala
MEX-119405–44742Tlaxcala, Puebla
  • Mile 71 of this route: Tabasco → Veracruz (state line)
  • Mile 319 of this route: Veracruz → Puebla (state line)
  • Mile 378 of this route: Puebla → Tlaxcala (state line)
  • Mile 423 of this route: Tlaxcala → Puebla (state line)

Stops between Comalcalco and Zacatlán

  • Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 306), Museo Nacional del Títere (mile 386)
  • Nature and outdoors: Cañón del Río Blanco National Park (mile 306)
  • Museums and history: La Venta (mile 68), Orizaba Cathedral (mile 298), Museo Nacional del Títere (mile 386), Museo Casa de Piedra (mile 403)

La Venta

Mile 68 · Archaeological site · 3 mi from the route · side trip; actual detour depends on access roads

Once an important Olmec city, La Venta sits in Tabasco close to Huimanguillo. Monumental sandstone sculptures found at the foot of its main pyramid are among the 200-plus pieces in the site museum.

Teatro Pedro Díaz

Mile 284 · Theater · 2 mi from the route

In downtown Córdoba, the Teatro Pedro Díaz was built in the late 19th century by Pedro Díaz to a design by engineer A. Durán; its facade was remodeled in 1905.

Orizaba Cathedral

Mile 298 · Cathedral · 1 mi from the route

The Cathedral of St. Michael the Archangel is the main Catholic church of Orizaba, in the state of Veracruz, and the seat of the Diocese of Orizaba.

Cañón del Río Blanco National Park

Mile 306 · National park · 0.5 mi from the route

Veracruz is home to Cañón del Río Blanco National Park, a natural area that the Mexican government has set aside for protection.

Museo Nacional del Títere

Mile 386 · Museum · 0.9 mi from the route

On the main square of Huamantla, the National Puppet Museum (Museo Nacional del Títere) fills eight galleries with puppets from Mexico and abroad, including pieces tied to the Rosete Aranda family, whose company toured Mexico for generations.

Museo Casa de Piedra

Mile 403 · Railway museum · 2 mi from the route · side trip; actual detour depends on access roads

Apizaco's old railroad station, dating from 1916, now houses the Museo Casa de Piedra. Inside, photographs and documents trace the town's history, especially its long ties to the railroads.

Santuario de Nuestro Padre Jesús de Aquixtla

Mile 435 · Sanctuary · 1 mi from the route

In the Sierra Norte de Puebla, the sanctuary of Nuestro Padre Jesús in Aquixtla draws thousands of pilgrims during the year who come to give thanks for favors received.

More drives to Zacatlán

From Comalcalco to other places in Mexico

Frequently asked questions

How long is the drive from Comalcalco to Zacatlán?

About 7 h 59 min of driving without stops, over 447 miles.

How far is Zacatlán from Comalcalco by car?

About 447 miles (719 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Comalcalco to Zacatlán?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Comalcalco to Zacatlán?

The U.S. State Department rates Tabasco Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

Which highways go from Comalcalco to Zacatlán?

In order: MEX-187, MEX-180, MEX-180D, MEX-145D, MEX-150D, MEX-136 and MEX-119. The road-by-road table above shows the route miles for each one.

What are good stops between Comalcalco and Zacatlán?

Closest to the road: Orizaba Cathedral (cathedral, mile 298, 1 mi from the route); Cañón del Río Blanco National Park (national park, mile 306, 0.5 mi from the route); Museo Nacional del Títere (museum, mile 386, 0.9 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.