Plan on about 8 h 6 min of driving for the 474-mile (763 km) trip from Comalcalco to Tepoztlán, before any stops.
| Distance | 474 mi (763 km) |
|---|---|
| Time at the wheel, no stops | 8 h 6 min |
| Main roads, in order | MEX-187 → MEX-180 → MEX-180D → MEX-145D → MEX-150D → MEX-190 → PUE 438D → MEX-160 → MEX-160D |
| Mexican states on the route | Tabasco, Veracruz, Puebla, Morelos |
| Toll roads (as marked in OpenStreetMap) | MEX-180D, MEX-145D, MEX-150D, MEX-160D |
| Fuel estimate (car at 25 mpg) | about 19.0 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
On the road from Comalcalco to Tepoztlán
MEX-145D (142 mi) and MEX-150D (131 mi) carry about 58% of the 474 miles. It runs through 4 states: Tabasco, Veracruz, Puebla, Morelos. OpenStreetMap marks tolled sections on MEX-180D, MEX-145D and MEX-150D. Of the 9 stops listed below, 1 are within a mile of the road.
Roads you'll take from Comalcalco to Tepoztlán
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| MEX-187 | 0–24 | 24 | Tabasco |
| connecting roads | 24–25 | 1 | Tabasco |
| MEX-180 | 25–35 | 10 | Tabasco |
| MEX-180D | 35–68 | 33 | Tabasco |
| MEX-180 | 68–88 | 20 | Tabasco, Veracruz |
| MEX-180D | 88–109 | 21 | Veracruz |
| MEX-145D | 109–251 | 142 | Veracruz |
| MEX-150D | 251–382 | 131 | Veracruz, Puebla |
| connecting roads | 382–383 | 1 | Puebla |
| MEX-190 | 383–398 | 15 | Puebla |
| local roads | 398–409 | 11 | Puebla |
| PUE 438D | 409–442 | 33 | Puebla, Morelos |
| connecting roads | 442–443 | 1 | Morelos |
| MEX-160 | 443–459 | 16 | Morelos |
| MEX-160D | 459–472 | 13 | Morelos |
| local roads | 472–474 | 2 | Morelos |
- Mile 71 of this route: Tabasco → Veracruz (state line)
- Mile 319 of this route: Veracruz → Puebla (state line)
- Mile 435 of this route: Puebla → Morelos (state line)
What to see on the way from Comalcalco to Tepoztlán
- Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 306)
- Nature and outdoors: Cañón del Río Blanco National Park (mile 306)
- Museums and history: La Venta (mile 68), Huatusco (mile 258), Orizaba Cathedral (mile 298), Convent Church of Santo Domingo, Puebla (mile 388), International Museum of the Baroque (mile 398), Museo Histórico del Oriente de Morelos "Casa de Morelos" (mile 457)
La Venta
Once an important Olmec city, La Venta sits in Tabasco close to Huimanguillo. Monumental sandstone sculptures found at the foot of its main pyramid are among the 200-plus pieces in the site museum.
Huatusco
Above the Atoyac River in Carrillo Puerto, Cuauhtochco has a Mexica-era temple that still keeps original surface finishes. Expect no visitor facilities, and consider hiring a local guide.
Orizaba Cathedral
The Cathedral of St. Michael the Archangel is the main Catholic church of Orizaba, in the state of Veracruz, and the seat of the Diocese of Orizaba.
Cañón del Río Blanco National Park
Veracruz is home to Cañón del Río Blanco National Park, a natural area that the Mexican government has set aside for protection.
Convent Church of Santo Domingo, Puebla
Behind the facade of Puebla's Santo Domingo church hides the Capilla del Rosario, inaugurated in 1690. Gold covers its walls, pilasters and vaults, and contemporaries hailed it as the eighth wonder of the New World.
International Museum of the Baroque
Designed by Japanese architect Toyo Ito and opened in 2016, Puebla's baroque museum wraps its galleries in curving white concrete walls beside a reflecting pond. Exhibits cover baroque painting, sculpture, architecture, music, theater and literature.
Tonantzintla Observatory
The Tonantzintla Observatory in Puebla was home to the National Astrophysical Observatory directed by Guillermo Haro. Its main instrument, a Schmidt camera, was a wide-field telescope built for photographing the sky.
Museo Histórico del Oriente de Morelos "Casa de Morelos"
In this 18th-century house in Cuautla, José María Morelos lived during the 1812 Siege of Cuautla. Its INAH galleries trace regional history through Morelos and Emiliano Zapata and display "El Niño," his first cannon, a gift from the Galeana family.
Templo y Exconvento de San Mateo Apóstol
Built by Augustinian friars, the Templo y Exconvento de San Mateo Apóstol in Atlatlahucan is well preserved, with murals and decorated vaults, and is associated with the origins of the Chinelo dancers.
Once you reach Tepoztlán
Tepoztlán Ex Convento Museum
Tepoztlán's Dominican monastery, built between 1555 and 1580, keeps original 16th-century murals in its cloister. Upstairs, the museum covers local daily life, faith, festivals and dances, and the complex is part of a UNESCO World Heritage listing.
Museo Carlos Pellicer
Tepoztlán's Museo de Arte Prehispánico Carlos Pellicer, opened in 1965 and named for the poet and museographer, displays a collection of pre-Hispanic objects in the former granary of the Church of Nuestra Señora de la Natividad.
El Tepozteco National Park
Eroded volcanic hills of the Sierra de Tepoztlán fill this national park, about half of which lies in Mexico City's Milpa Alta borough. A short, steep climb leads to the Tepozteco archaeological zone; wear good shoes, since the rocks get slippery.
More drives to Tepoztlán
- Mexico City to Tepoztlán
- Metepec to Tepoztlán
- Toluca to Tepoztlán
- Atlixco to Tepoztlán
- Taxco to Tepoztlán
- Tepotzotlán to Tepoztlán
From Comalcalco to other places in Mexico
- Comalcalco to Huejotzingo
- Comalcalco to Tlaxco
- Comalcalco to Calpulalpan
- Comalcalco to Tetela del Volcán
- Comalcalco to Zacatlán
- Comalcalco to Otumba
Continue Your Adventure
Frequently asked questions
How long does it take to drive from Comalcalco to Tepoztlán?
About 8 h 6 min of driving without stops, over 474 miles.
How far is Tepoztlán from Comalcalco by car?
About 474 miles (763 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Comalcalco to Tepoztlán?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Comalcalco to Tepoztlán?
The U.S. State Department rates Tabasco Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Morelos Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.
Which highways go from Comalcalco to Tepoztlán?
In order: MEX-187, MEX-180, MEX-180D, MEX-145D, MEX-150D, MEX-190, PUE 438D, MEX-160 and MEX-160D. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Comalcalco to Tepoztlán?
Closest to the road: Orizaba Cathedral (cathedral, mile 298, 1 mi from the route); Cañón del Río Blanco National Park (national park, mile 306, 0.5 mi from the route); International Museum of the Baroque (art museum, mile 398, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.