The Wayro route from Uruapan to Zacatecas is 331 miles (532 km), about 5 h 44 min of driving without stops.
| Distance | 331 mi (532 km) |
|---|---|
| Driving time, no stops | 5 h 44 min |
| Main roads, in order | MEX-14D → MEX-37D → MEX-15D → MEX-43D → MEX-45D → MEX-45 |
| Mexican states on the route | Michoacán (Level 4), Guanajuato (Level 3), Jalisco (Level 3), Aguascalientes (Level 2), Zacatecas (Level 4) |
| Toll roads | MEX-14D, MEX-37D, MEX-15D, MEX-43D, MEX-45D |
| Fuel estimate (car at 25 mpg) | about 13.2 gal; actual use varies by vehicle and traffic |
| Stops listed below | 6 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Uruapan to Zacatecas is like
MEX-45D (128 mi) and MEX-45 (68 mi) carry about 59% of the 331 miles. MEX-14D, MEX-37D, MEX-15D, MEX-43D, MEX-45D are toll highways (cuota); MEX-45 is a free federal road (libre). It runs through 5 states: Michoacán, Guanajuato, Jalisco, Aguascalientes, Zacatecas. Of the 6 stops listed below, 1 are within a mile of the road.
The route from Uruapan to Zacatecas, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–4 | 4 | Michoacán |
| MEX-14D | 4–37 | 33 | Michoacán |
| MEX-37D | 37–75 | 38 | Michoacán |
| MEX-15D | 75–79 | 4 | Michoacán |
| connecting roads | 79–80 | 1 | Michoacán |
| MEX-43D | 80–131 | 51 | Michoacán, Guanajuato |
| MEX-45D | 131–239 | 108 | Guanajuato, Jalisco |
| MEX-45 | 239–269 | 30 | Jalisco, Aguascalientes |
| local roads | 269–272 | 3 | Aguascalientes |
| MEX-45 | 272–301 | 29 | Aguascalientes, Zacatecas |
| MEX-45D | 301–321 | 20 | Zacatecas |
| connecting roads | 321–322 | 1 | Zacatecas |
| MEX-45 | 322–331 | 9 | Zacatecas |
- Mile 95 of this route: Michoacán → Guanajuato (state line)
- Mile 194 of this route: Guanajuato → Jalisco (state line)
- Mile 243 of this route: Jalisco → Aguascalientes (state line)
- Mile 296 of this route: Aguascalientes → Zacatecas (state line)
Stops between Uruapan and Zacatecas
- Right off the route (under 1 mile): Aguascalientes Museum (mile 258)
- Nature and outdoors: La Pona (mile 258)
- Museums and history: Basilica of Nuestra Señora de la Salud, Pátzcuaro (mile 33), Museo de Artes e Industrias Populares (mile 33), Aguascalientes Museum (mile 258), Museo de la Insurgencia (mile 278)
Basilica of Nuestra Señora de la Salud, Pátzcuaro
Pátzcuaro's basilica (Basílica de Nuestra Señora de la Salud) rises on pre-Hispanic platforms beside its own plaza. Bishop Vasco de Quiroga planned it as a five-nave cathedral, only one nave was finished, and his remains rest inside.
Museo de Artes e Industrias Populares
Housed in an 18th-century building adapted from the Colegio de San Nicolás, which Vasco de Quiroga founded in the 16th century, this INAH museum in Pátzcuaro shows Purépecha pottery, textiles, woodwork and lacquerware.
Historic Centre of Morelia
Morelia's old core, founded in the 16th century as Valladolid, keeps more than 200 historic buildings in the region's pink stone around its cathedral and checkerboard streets. UNESCO added it to the World Heritage List in 1991.
Aguascalientes Museum
Located in the state capital, the Aguascalientes Museum is the city's art museum, set in the city of Aguascalientes, Mexico.
La Pona
Inside the city of Aguascalientes, La Pona protects a native mesquite woodland as an ecological conservation zone, with a quiet forest area for walks and a separate section with sports and recreation spaces.
Museo de la Insurgencia
Set in a 17th-century estate, the Museo de la Insurgencia opened in 1964 to tell the story of Mexico's independence movement. One hall shows farm, mining and textile tools from hacienda work; another displays everyday objects from past eras.
When you get to Zacatecas
Zacatecas climbs the steep slopes of a narrow valley between the Bufa and Grillo hills in north-central Mexico. Founded in 1546 after the discovery of a rich silver lode, its historic center has been a UNESCO World Heritage Site since 1993, and the city is also part of the Camino Real de Tierra Adentro, the colonial silver route listed by UNESCO in 2010.
- Zacatecas Cathedral: Built between 1730 and 1760, the cathedral dominates downtown with Baroque façades that mix European and Indigenous decorative elements. source
- Teatro Calderón: The downtown theater dates from 1834 and is one of the civic landmarks UNESCO highlights in the historic center. source
- Mercado González Ortega: The iron-framed market building from 1886 stands in the historic center near the cathedral. source
Cathedral Basilica of Zacatecas
Dedicated to the Virgin of the Assumption, the Cathedral of Zacatecas is the main church of the Diocese of Zacatecas.
Museo Toma de Zacatecas
On the Cerro de la Bufa, this museum explains the military and social story behind the Taking of Zacatecas during the Mexican Revolution, along with glimpses of daily life in the city at the time.
Teatro Fernando Calderón
Built between 1891 and 1897 to plans by architect George Edward King, Zacatecas' Teatro Calderón honors playwright Fernando Calderón and witnessed violent events during the Toma de Zacatecas.
More drives to Zacatecas
- Del Rio, TX to Zacatecas
- South Padre Island, TX to Zacatecas
- McAllen, TX to Zacatecas
- Laredo, TX to Zacatecas
- Corpus Christi, TX to Zacatecas
- Brownsville, TX to Zacatecas
From Uruapan to other places in Mexico
- Uruapan to Amatitán
- Uruapan to Tequila
- Uruapan to Pabellón de Arteaga
- Uruapan to Pabellón de Hidalgo
- Uruapan to San José de Gracia, Aguascalientes
- Uruapan to Real de Asientos
Coming to Zacatecas from the United States? Border crossings, permits and routes from U.S. cities: Driving to Zacatecas, Mexico from the U.S.
Continue Your Adventure
Frequently asked questions
How long is the drive from Uruapan to Zacatecas?
About 5 h 44 min of driving without stops, over 331 miles.
How far is Zacatecas from Uruapan by car?
About 331 miles (532 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Uruapan to Zacatecas?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Uruapan to Zacatecas?
The U.S. State Department rates Michoacán Level 4: Do Not Travel; Guanajuato Level 3: Reconsider Travel; Jalisco Level 3: Reconsider Travel; Aguascalientes Level 2: Exercise Increased Caution; Zacatecas Level 4: Do Not Travel (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Uruapan to Zacatecas use?
In order: MEX-14D, MEX-37D, MEX-15D, MEX-43D, MEX-45D and MEX-45. The road-by-road table above shows the route miles and states for each one.
What are good stops between Uruapan and Zacatecas?
Closest to the road: Museo de Artes e Industrias Populares (museum, mile 33, 1 mi from the route); Basilica of Nuestra Señora de la Salud, Pátzcuaro (minor basilica, mile 33, 2 mi from the route); Aguascalientes Museum (art museum, mile 258, 0.4 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.