The Wayro route from Laredo to Zacatecas is 418 miles (673 km), about 8 h 9 min of driving without stops. The U.S.–Mexico border is at about mile 1 on this route, near the Laredo port of entry.
What the State Department tells travelers on this route:
- Nuevo León: “Those traveling between the U.S. border and Monterrey on highways 85/85D, 54, and 40/40D should exercise caution and avoid travel after dark.”
- Nuevo León: “Armed robberies and carjackings have occurred along these highways even during daylight hours.”
| Distance | 418 mi (673 km) |
|---|---|
| Driving time, no stops | 8 h 9 min |
| Main roads, in order | MEX-85 → MEX-85D → NL 100D → MEX-40D → MEX-54 → MEX-45 |
| Border crossing | about mile 1 of this route, Texas → Tamaulipas (near the Laredo, TX port of entry) |
| Mexican states on the route | Tamaulipas (Level 4), Nuevo León (Level 2), Coahuila (Level 3), Zacatecas (Level 4) |
| Toll roads | MEX-85D, MEX-40D |
| Fuel estimate (car at 25 mpg) | about 16.7 gal; actual use varies by vehicle and traffic |
| Stops listed below | 0 |
Crossing into Mexico: what you need for Zacatecas
| Passport | Passport book or passport card to enter Mexico by land |
|---|---|
| FMM entry permit | Required for this trip: Zacatecas is well beyond the 12-mile (20 km) border zone where the permit is not needed |
| Temporary vehicle import permit (TIP) | Required for a U.S.-registered vehicle this far into Mexico |
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you cross |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
Crossing at Laredo
Laredo reaches Nuevo Laredo over several city-run bridges. Gateway to the Americas (Bridge I) handles pedestrians and cars and has SENTRI lanes, Juárez-Lincoln (Bridge II) takes cars and buses, and the World Trade Bridge is for commercial trucks.
What the drive from Laredo to Zacatecas is like
MEX-54 (208 mi) and MEX-85 (120 mi) carry about 78% of the 418 miles. The U.S. part of the drive runs through Texas for about 1 miles; after the border at Laredo you have about 417 miles left in Mexico. The Mexican leg uses MEX-85D, MEX-40D, toll highways (cuota).
The route from Laredo to Zacatecas, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | Texas |
| MEX-85 | 1–121 | 120 | Tamaulipas, Nuevo León |
| MEX-85D | 121–126 | 5 | Nuevo León |
| NL 100D | 126–149 | 23 | Nuevo León |
| connecting roads | 149–150 | 1 | Nuevo León |
| MEX-40D | 150–200 | 50 | Nuevo León, Coahuila |
| MEX-54 | 200–408 | 208 | Coahuila, Zacatecas |
| MEX-45 | 408–417 | 9 | Zacatecas |
| local roads | 417–418 | 1 | Zacatecas |
- Mile 1 of this route: Texas → Tamaulipas (international border)
- Mile 28 of this route: Tamaulipas → Nuevo León (state line)
- Mile 162 of this route: Nuevo León → Coahuila (state line)
- Mile 239 of this route: Coahuila → Zacatecas (state line)
When you get to Zacatecas
Zacatecas climbs the steep slopes of a narrow valley between the Bufa and Grillo hills in north-central Mexico. Founded in 1546 after the discovery of a rich silver lode, its historic center has been a UNESCO World Heritage Site since 1993, and the city is also part of the Camino Real de Tierra Adentro, the colonial silver route listed by UNESCO in 2010.
- Zacatecas Cathedral: Built between 1730 and 1760, the cathedral dominates downtown with Baroque façades that mix European and Indigenous decorative elements. source
- Teatro Calderón: The downtown theater dates from 1834 and is one of the civic landmarks UNESCO highlights in the historic center. source
- Mercado González Ortega: The iron-framed market building from 1886 stands in the historic center near the cathedral. source
Cathedral Basilica of Zacatecas
Dedicated to the Virgin of the Assumption, the Cathedral of Zacatecas is the main church of the Diocese of Zacatecas.
More drives to Zacatecas
- Del Rio, TX to Zacatecas
- South Padre Island, TX to Zacatecas
- McAllen, TX to Zacatecas
- Corpus Christi, TX to Zacatecas
- Brownsville, TX to Zacatecas
From Laredo to other places in Mexico
- Laredo, TX to Piedras Negras
- Laredo, TX to Gómez Palacio
- Laredo, TX to Ciudad Victoria
- Laredo, TX to Reynosa
- Laredo, TX to Linares
- Laredo, TX to Jerez
All routes to Zacatecas, border crossings and permits in one place: Driving to Zacatecas, Mexico from the U.S.
Continue Your Adventure
Frequently asked questions
How long is the drive from Laredo to Zacatecas?
About 8 h 9 min of driving without stops, over 418 miles.
How far is Zacatecas from Laredo by car?
About 418 miles (673 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Laredo to Zacatecas drive cross into Mexico?
At about mile 1 of this route, from Texas into Tamaulipas, near the Laredo port of entry.
Do I need a permit to drive my car from Laredo to Zacatecas?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car this far into Mexico. You also need Mexican auto insurance and a passport book or card. An FMM entry permit is required too.
Is it safe to drive from Laredo to Zacatecas?
The U.S. State Department rates Tamaulipas Level 4: Do Not Travel; Nuevo León Level 2: Exercise Increased Caution; Coahuila Level 3: Reconsider Travel; Zacatecas Level 4: Do Not Travel (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Laredo to Zacatecas use?
In order: MEX-85, MEX-85D, NL 100D, MEX-40D, MEX-54 and MEX-45. The road-by-road table above shows the route miles and states for each one.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.