The Wayro route from Tuxtepec to Tepotzotlán is 299 miles (481 km), about 5 h 45 min of driving without stops.
| Distance | 299 mi (481 km) |
|---|---|
| Driving time, no stops | 5 h 45 min |
| Main roads, in order | MEX-175 → MEX-145 → MEX-150D → MEX-M40D → MEX-136 → MEX-142 → MEX-132 |
| Mexican states on the route | Oaxaca (Level 2), Veracruz (Level 2), Puebla (Level 2), Tlaxcala (Level 2), State of Mexico (Level 2) |
| Toll roads | MEX-145D, MEX-150D, MEX-M40D |
| Fuel estimate (car at 25 mpg) | about 12.0 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Tuxtepec to Tepotzotlán is like
MEX-150D (156 mi) and MEX-145 (49 mi) carry about 69% of the 299 miles. MEX-150D, MEX-M40D are toll highways (cuota); MEX-175, MEX-145, MEX-136, MEX-142, MEX-132 are free federal roads (libre). It runs through 5 states: Oaxaca, Veracruz, Puebla, Tlaxcala, State of Mexico. Of the 8 stops listed below, 3 are within a mile of the road.
The route from Tuxtepec to Tepotzotlán, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | Oaxaca |
| MEX-175 | 1–7 | 6 | Oaxaca, Veracruz |
| MEX-145 | 7–56 | 49 | Veracruz |
| connecting roads | 56–60 | 4 | Veracruz |
| MEX-150D | 60–216 | 156 | Veracruz, Puebla |
| connecting roads | 216–217 | 1 | Puebla |
| MEX-M40D | 217–235 | 18 | Puebla, Tlaxcala |
| MEX-136 | 235–269 | 34 | Tlaxcala, State of Mexico |
| MEX-142 | 269–278 | 9 | State of Mexico |
| MEX-132 | 278–282 | 4 | State of Mexico |
| connecting roads | 282–283 | 1 | State of Mexico |
| local roads | 283–299 | 16 | State of Mexico |
- Mile 4 of this route: Oaxaca → Veracruz (state line)
- Mile 128 of this route: Veracruz → Puebla (state line)
- Mile 221 of this route: Puebla → Tlaxcala (state line)
- Mile 255 of this route: Tlaxcala → State of Mexico (state line)
Stops between Tuxtepec and Tepotzotlán
- Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 115), Los Volcanes Biosphere Reserve (mile 252), Texcoco Cathedral (mile 267)
- Nature and outdoors: Cañón del Río Blanco National Park (mile 115), Los Volcanes Biosphere Reserve (mile 252), Los Remedios National Park (mile 292)
- Museums and history: Huatusco (mile 66), Museo Regional de la Revolución Mexicana (mile 196), Tepetlaoztoc (mile 262), Texcoco Cathedral (mile 267), Paleontological Museum in Tocuila (mile 269)
Huatusco
Above the Atoyac River in Carrillo Puerto, the ruins of Huatusco (Cuauhtochco) include a Mexica-era temple that still keeps original surface finishes. There are no visitor facilities; reaching it means crossing a suspension bridge and climbing a steep trail, ideally with a local guide.
Cañón del Río Blanco National Park
Cañón del Río Blanco National Park is a protected natural area in the Mexican state of Veracruz, set aside by the government as a national park.
Museo Regional de la Revolución Mexicana
The Serdán family home in downtown Puebla, now the Museo Regional de la Revolución Mexicana, recalls Aquiles, Máximo and Carmen Serdán and the start of the 1910 Revolution. It opened in 1960.
Los Volcanes Biosphere Reserve
Surrounding the volcanoes Popocatépetl and Iztaccíhuatl, Los Volcanes is a UNESCO biosphere reserve in the Trans-Mexican Volcanic Belt, where North American and tropical wildlife zones meet.
Tepetlaoztoc
Tepetlaoztoc, also spelled Tepetlaoxtoc, was an Aztec-Nahua settlement of the Late Postclassic period in central Mexico, and it stayed occupied into the colonial era.
Texcoco Cathedral
Texcoco's Cathedral of the Immaculate Conception occupies a former convent built by the Franciscans in the 16th century, one of the order's early convent complexes in the Americas.
Paleontological Museum in Tocuila
The Paleontological Museum in Tocuila, in Texcoco, State of Mexico, is a fossil museum displaying part of a rich deposit of Late Pleistocene animals from the Americas.
Los Remedios National Park
Los Remedios National Park, created by federal decree in 1938, covers about 400 hectares on the far western side of Naucalpan, just northwest of Mexico City.
When you get to Tepotzotlán
Parque de las Esculturas
Seventeen sculptures by Charlotte Yazbek, first shown at the Mexico Pavilion of the 1964 New York World's Fair, stand in this Cuautitlán Izcalli park. The artist oversaw their installation here in 1976.
Cuautitlán Cathedral
Cuautitlán's St. Bonaventure Cathedral (Catedral de San Buenaventura) is a Catholic church that forms part of the convent of the same name in this State of Mexico municipality.
Parque Espejo de los Lirios
Espejo de los Lirios is a lake park in Cuautitlán Izcalli, opened as a park in 1973 and declared a protected natural area in 2009 along with the city's Central Park.
More drives to Tepotzotlán
- Mexico City to Tepotzotlán
- Toluca to Tepotzotlán
- Cuernavaca to Tepotzotlán
- Cuautla to Tepotzotlán
- Celaya to Tepotzotlán
- San Miguel de Allende to Tepotzotlán
From Tuxtepec to other places in Mexico
- Tuxtepec to Zacatelco
- Tuxtepec to Huejotzingo
- Tuxtepec to Calpulalpan
- Tuxtepec to Otumba
- Tuxtepec to Tlaltizapán
- Tuxtepec to Tepoztlán
Continue Your Adventure
Frequently asked questions
How long is the drive from Tuxtepec to Tepotzotlán?
About 5 h 45 min of driving without stops, over 299 miles.
How far is Tepotzotlán from Tuxtepec by car?
About 299 miles (481 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Tuxtepec to Tepotzotlán?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Tuxtepec to Tepotzotlán?
The U.S. State Department rates Oaxaca Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Tuxtepec to Tepotzotlán use?
In order: MEX-175, MEX-145, MEX-150D, MEX-M40D, MEX-136, MEX-142 and MEX-132. The road-by-road table above shows the route miles and states for each one.
What are good stops between Tuxtepec and Tepotzotlán?
Closest to the road: Cañón del Río Blanco National Park (National Park of Mexico, mile 115, 0.6 mi from the route); Los Volcanes Biosphere Reserve (biosphere reserve, mile 252, 0.6 mi from the route); Texcoco Cathedral (cathedral, mile 267, 0.8 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.