The Wayro route from Tuxtepec to Tlaltizapán is 280 miles (451 km), about 5 h 25 min of driving without stops.
| Distance | 280 mi (451 km) |
|---|---|
| Driving time, no stops | 5 h 25 min |
| Main roads, in order | MEX-175 → MEX-145 → MEX-150D → MEX-190 → PUE 438D → MEX-94D → MOR 9 |
| Mexican states on the route | Oaxaca (Level 2), Veracruz (Level 2), Puebla (Level 2), Morelos (Level 3) |
| Toll roads | MEX-145D, MEX-150D, MEX-94D |
| Fuel estimate (car at 25 mpg) | about 11.2 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Tuxtepec to Tlaltizapán is like
MEX-150D (131 mi) and MEX-145 (49 mi) carry about 64% of the 280 miles. MEX-150D, MEX-94D are toll highways (cuota); MEX-175, MEX-145, MEX-190 are free federal roads (libre). It runs through 4 states: Oaxaca, Veracruz, Puebla, Morelos. Of the 8 stops listed below, 1 are within a mile of the road.
The route from Tuxtepec to Tlaltizapán, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | Oaxaca |
| MEX-175 | 1–7 | 6 | Oaxaca, Veracruz |
| MEX-145 | 7–56 | 49 | Veracruz |
| connecting roads | 56–60 | 4 | Veracruz |
| MEX-150D | 60–191 | 131 | Veracruz, Puebla |
| MEX-190 | 191–206 | 15 | Puebla |
| local roads | 206–217 | 11 | Puebla |
| PUE 438D | 217–251 | 34 | Puebla, Morelos |
| MEX-94D | 251–268 | 17 | Morelos |
| connecting roads | 268–270 | 2 | Morelos |
| MOR 9 | 270–278 | 8 | Morelos |
| local roads | 278–280 | 2 | Morelos |
- Mile 4 of this route: Oaxaca → Veracruz (state line)
- Mile 128 of this route: Veracruz → Puebla (state line)
- Mile 244 of this route: Puebla → Morelos (state line)
Stops between Tuxtepec and Tlaltizapán
- Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 115)
- Nature and outdoors: Cañón del Río Blanco National Park (mile 115)
- Museums and history: Cathedral of Córdoba, Veracruz (mile 93), Orizaba Cathedral (mile 106), Convent Church of Santo Domingo, Puebla (mile 196), International Museum of the Baroque (mile 206), Las Pilas archaeological site (mile 253)
Cathedral of Córdoba, Veracruz
Built in the first half of the 17th century, Córdoba's Immaculate Conception Cathedral is the city's main church; look up to see its octagonal dome covered in tiles, finished in a neoclassical style.
Orizaba Cathedral
The Cathedral of St. Michael the Archangel is the main Catholic church of Orizaba, in the state of Veracruz, and the seat of the Diocese of Orizaba.
Cañón del Río Blanco National Park
Cañón del Río Blanco National Park is a protected natural area in the Mexican state of Veracruz, set aside by the government as a national park.
Convent Church of Santo Domingo, Puebla
Behind the facade of Puebla's Santo Domingo church hides the Capilla del Rosario, inaugurated in 1690. Gold covers its walls, pilasters and vaults, and contemporaries hailed it as the eighth wonder of the New World.
Historic centre of Puebla
Laid out from scratch in 1531, Puebla's UNESCO-listed core is a grid of tile-covered houses, colonial churches and the 16th–17th-century cathedral, with the old archbishop's palace that houses the Palafox Library, established in 1646.
International Museum of the Baroque
Designed by Japanese architect Toyo Ito and opened in 2016, Puebla's baroque museum wraps its galleries in curving white concrete walls beside a reflecting pond. Exhibits cover baroque painting, sculpture, architecture, music, theater and literature.
Monasteries on the slopes of Popocatépetl
Inscribed by UNESCO in 1994, this World Heritage site groups early 16th-century monasteries that Franciscan, Dominican and Augustinian friars built on the slopes of Popocatépetl, with large open spaces used to evangelize the Indigenous population.
Las Pilas archaeological site
Set inside a bathing park in Jonacatepec, Las Pilas was a ceremonial center devoted to water, where inhabitants built channels to collect and store underground water for irrigation; burials were found within the channel system.
When you get to Tlaltizapán
Xochicalco
A fortified hilltop city that thrived between about 650 and 900, Xochicalco is a UNESCO World Heritage site where you can see the Pyramid of the Plumed Serpent with its carved reliefs, ball courts, an underground observatory and a site museum.
More drives to Tlaltizapán
- Tetela del Volcán to Tlaltizapán
- Atlixco to Tlaltizapán
- Mexico City to Tlaltizapán
- Metepec to Tlaltizapán
- Zacatelco to Tlaltizapán
- Tlaxcala to Tlaltizapán
From Tuxtepec to other places in Mexico
- Tuxtepec to Zacatelco
- Tuxtepec to Huejotzingo
- Tuxtepec to Calpulalpan
- Tuxtepec to Otumba
- Tuxtepec to Tepoztlán
- Tuxtepec to Tulancingo
Frequently asked questions
How long is the drive from Tuxtepec to Tlaltizapán?
About 5 h 25 min of driving without stops, over 280 miles.
How far is Tlaltizapán from Tuxtepec by car?
About 280 miles (451 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Tuxtepec to Tlaltizapán?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Tuxtepec to Tlaltizapán?
The U.S. State Department rates Oaxaca Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Morelos Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Tuxtepec to Tlaltizapán use?
In order: MEX-175, MEX-145, MEX-150D, MEX-190, PUE 438D, MEX-94D and MOR 9. The road-by-road table above shows the route miles and states for each one.
What are good stops between Tuxtepec and Tlaltizapán?
Closest to the road: Cañón del Río Blanco National Park (National Park of Mexico, mile 115, 0.6 mi from the route); International Museum of the Baroque (art museum, mile 206, 1 mi from the route); Las Pilas archaeological site (archaeological site, mile 253, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.