The Wayro route from Tuxtepec to Santa Fe de la Laguna is 484 miles (779 km), about 8 h 19 min of driving without stops.
| Distance | 484 mi (779 km) |
|---|---|
| Driving time, no stops | 8 h 19 min |
| Main roads, in order | MEX-175 → MEX-145 → MEX-150D → MEX-M40D → MEX-15D → MEX-37D → MEX-15 |
| Mexican states on the route | Oaxaca (Level 2), Veracruz (Level 2), Puebla (Level 2), Tlaxcala (Level 2), Hidalgo (Level 2), State of Mexico (Level 2), Michoacán (Level 4) |
| Toll roads | MEX-145D, MEX-150D, MEX-M40D, MEX-15D, MEX-37D |
| Fuel estimate (car at 25 mpg) | about 19.4 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Tuxtepec to Santa Fe de la Laguna is like
MEX-150D (156 mi) and MEX-M40D (139 mi) carry about 61% of the 484 miles. MEX-150D, MEX-M40D, MEX-15D, MEX-37D are toll highways (cuota); MEX-175, MEX-145, MEX-15 are free federal roads (libre). It runs through 7 states: Oaxaca, Veracruz, Puebla, Tlaxcala, Hidalgo, State of Mexico, Michoacán. Of the 9 stops listed below, 1 are within a mile of the road.
The route from Tuxtepec to Santa Fe de la Laguna, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | Oaxaca |
| MEX-175 | 1–7 | 6 | Oaxaca, Veracruz |
| MEX-145 | 7–56 | 49 | Veracruz |
| connecting roads | 56–60 | 4 | Veracruz |
| MEX-150D | 60–216 | 156 | Veracruz, Puebla |
| connecting roads | 216–217 | 1 | Puebla |
| MEX-M40D | 217–356 | 139 | Puebla, Tlaxcala, Hidalgo, State of Mexico |
| connecting roads | 356–357 | 1 | State of Mexico |
| MEX-15D | 357–447 | 90 | State of Mexico, Michoacán |
| MEX-37D | 447–468 | 21 | Michoacán |
| MEX-15 | 468–484 | 16 | Michoacán |
- Mile 4 of this route: Oaxaca → Veracruz (state line)
- Mile 128 of this route: Veracruz → Puebla (state line)
- Mile 221 of this route: Puebla → Tlaxcala (state line)
- Mile 244 of this route: Tlaxcala → Hidalgo (state line)
- Mile 252 of this route: Hidalgo → State of Mexico (state line)
- Mile 265 of this route: State of Mexico → Hidalgo (state line)
- Mile 281 of this route: Hidalgo → State of Mexico (state line)
- Mile 295 of this route: State of Mexico → Hidalgo (state line)
- Mile 326 of this route: Hidalgo → State of Mexico (state line)
- Mile 375 of this route: State of Mexico → Michoacán (state line)
Stops between Tuxtepec and Santa Fe de la Laguna
- Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 115)
- Nature and outdoors: Cañón del Río Blanco National Park (mile 115), Rayón National Park (mile 378)
- Museums and history: Orizaba Cathedral (mile 106), Museo Bello (mile 197), Jorge R. Acosta Museum (mile 312), Cathedral of Atlacomulco (mile 357)
Orizaba Cathedral
The Cathedral of St. Michael the Archangel is the main Catholic church of Orizaba, in the state of Veracruz, and the seat of the Diocese of Orizaba.
Cañón del Río Blanco National Park
Cañón del Río Blanco National Park is a protected natural area in the Mexican state of Veracruz, set aside by the government as a national park.
Teatro Principal
The Teatro Principal is a historic theater in the city of Puebla that is still active as a stage for performances.
Museo Bello
Puebla's Museo José Luis Bello y González shows the collection of industrialist José Luis Bello y González and his son: paintings, Talavera, featherwork, furniture, porcelain, ivory, glass and metalwork from America, Europe and Asia.
Exconvent of Santa María Magdalena
The former convent of Santa María Magdalena (Exconvento de Santa María Magdalena) is a 17th-century Baroque church built by the Dieguino friars, still in use as a Catholic temple of the Archdiocese of Puebla.
Jorge R. Acosta Museum
Next to the Tula ruins, the Museo de Sitio Jorge R. Acosta traces the rise and decline of the Toltecs and their city, Tollan Xicocotitlan. It moved into new facilities in 1982 and covers nearly 20 years of digs led by archaeologist Jorge R. Acosta.
Cathedral of Atlacomulco
Atlacomulco's cathedral, the Catedral de la Divina Providencia, is the seat of the Diocese of Atlacomulco and is dedicated to Divine Providence, making it the town's principal Catholic church.
Rayón National Park
Just outside Tlalpujahua, Rayón National Park (Parque Nacional Rayón) marks the start of the area's famous butterfly reserve country, which stretches south and west from here.
Historic Centre of Morelia
Morelia's old core, founded in the 16th century as Valladolid, keeps more than 200 historic buildings in the region's pink stone around its cathedral and checkerboard streets. UNESCO added it to the World Heritage List in 1991.
When you get to Santa Fe de la Laguna
Tzintzuntzan
Once the political and economic capital of the Purépecha empire, governed by a hereditary line of uacúsecha, or 'eagle lords,' Tzintzuntzan preserves its yácatas, temple bases that combine rectangular and semicircular platforms around ritual plazas.
More drives to Santa Fe de la Laguna
- Pedro Escobedo to Santa Fe de la Laguna
- Amatitán to Santa Fe de la Laguna
- Cadereyta to Santa Fe de la Laguna
- Tequila to Santa Fe de la Laguna
- Zimapán to Santa Fe de la Laguna
- San José de Gracia, Aguascalientes to Santa Fe de la Laguna
From Tuxtepec to other places in Mexico
- Tuxtepec to Zacatelco
- Tuxtepec to Huejotzingo
- Tuxtepec to Calpulalpan
- Tuxtepec to Otumba
- Tuxtepec to Tlaltizapán
- Tuxtepec to Tepoztlán
Continue Your Adventure
Frequently asked questions
How long is the drive from Tuxtepec to Santa Fe de la Laguna?
About 8 h 19 min of driving without stops, over 484 miles.
How far is Santa Fe de la Laguna from Tuxtepec by car?
About 484 miles (779 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Tuxtepec to Santa Fe de la Laguna?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Tuxtepec to Santa Fe de la Laguna?
The U.S. State Department rates Oaxaca Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Michoacán Level 4: Do Not Travel (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Tuxtepec to Santa Fe de la Laguna use?
In order: MEX-175, MEX-145, MEX-150D, MEX-M40D, MEX-15D, MEX-37D and MEX-15. The road-by-road table above shows the route miles and states for each one.
What are good stops between Tuxtepec and Santa Fe de la Laguna?
Closest to the road: Orizaba Cathedral (cathedral, mile 106, 1 mi from the route); Cañón del Río Blanco National Park (National Park of Mexico, mile 115, 0.6 mi from the route); Jorge R. Acosta Museum (museum, mile 312, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.