The Wayro route from Sedona to Guaymas is 554 miles (891 km), about 9 h 16 min of driving without stops. The U.S.–Mexico border is at about mile 294 on this route, near the Nogales port of entry.
| Distance | 554 mi (891 km) |
|---|---|
| Driving time, no stops | 9 h 16 min |
| Main roads, in order | AZ 179 → I-17 → I-10 → I-19 → MEX-15D → MEX-15 |
| Border crossing | about mile 294 of this route, Arizona → Sonora (near the Nogales, AZ port of entry) |
| Mexican states on the route | Sonora (Level 3) |
| Toll roads | MEX-15D |
| Fuel estimate (car at 25 mpg) | about 22.1 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
Crossing into Mexico: what you need for Guaymas
| Passport | Passport book or passport card to enter Mexico by land |
|---|---|
| FMM entry permit | Required for this trip: Guaymas is well beyond the 12-mile (20 km) border zone where the permit is not needed |
| Temporary vehicle import permit (TIP) | Not needed: Guaymas is inside Sonora's free zone (west of Highway 15 as far south as Empalme, plus a strip along the border that includes Cananea). Going farther south or east of Highway 15 requires a permit |
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you cross |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito. Sonora free zone: Explore Sonora.
Crossing at Nogales
Nogales, Arizona, and Nogales, Sonora, share several crossings: DeConcini downtown is the main gateway for visitors and daily crossers, Morley Gate nearby serves pedestrians, and Mariposa on the west side handles commercial trucks. The city is also home to Arizona's only rail crossing.
What the drive from Sedona to Guaymas is like
MEX-15D (147 mi) and I-17 (117 mi) carry about 48% of the 554 miles. The U.S. part of the drive runs through Arizona for about 294 miles; after the border at Nogales you have about 260 miles left in Mexico. The Mexican leg uses MEX-15D, a toll highway (cuota). Of the 8 stops listed below, 5 are within a mile of the road.
The route from Sedona to Guaymas, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | Arizona |
| AZ 179 | 1–15 | 14 | Arizona |
| I-17 | 15–132 | 117 | Arizona |
| I-10 | 132–229 | 97 | Arizona |
| connecting roads | 229–230 | 1 | Arizona |
| I-19 | 230–290 | 60 | Arizona |
| connecting roads | 290–293 | 3 | Arizona |
| MEX-15D | 293–301 | 8 | Arizona, Sonora |
| MEX-15 | 301–344 | 43 | Sonora |
| MEX-15D | 344–483 | 139 | Sonora |
| MEX-15 | 483–553 | 70 | Sonora |
| local roads | 553–554 | 1 | Sonora |
- Mile 294 of this route: Arizona → Sonora (international border)
Stops between Sedona and Guaymas
- Right off the route (under 1 mile): Montezuma Castle National Monument (mile 23), Cathedral of Saints Simon and Jude (mile 108), Arizona State Capitol (mile 114), Tumacácori National Historical Park (mile 274), Mission San Cayetano de Calabazas (mile 284)
- Nature and outdoors: Picacho Peak State Park (mile 189), Tumacácori National Historical Park (mile 274)
- Museums and history: Montezuma Castle National Monument (mile 23), Agua Fria National Monument (mile 62), Cathedral of Saints Simon and Jude (mile 108), Arizona State Capitol (mile 114), Casa Grande Ruins National Monument (mile 162), Tumacácori National Historical Park (mile 274), Mission San Cayetano de Calabazas (mile 284)
Montezuma Castle National Monument
Tucked into an alcove about 90 feet up a limestone cliff, this 20-room Sinagua dwelling is viewed from below. Established in 1906, the monument also includes Montezuma Well, a separate unit that once supplied the Sinagua with water.
Agua Fria National Monument
About 40 miles north of Phoenix off I-17, this BLM monument protects mesa-top pueblo ruins, petroglyph panels, and the Agua Fria River canyon, with hiking, birding, and primitive camping; much of Bloody Basin Road needs high clearance.
Cathedral of Saints Simon and Jude
Seat of the Roman Catholic Diocese of Phoenix since 1969, this cathedral was dedicated in 1966 and has welcomed Pope John Paul II in 1987 and Mother Teresa in 1989.
Arizona State Capitol
Built from 1898 to 1901 and topped by a copper dome and a Winged Victory weathervane, Arizona's historic capitol now houses the Arizona Capitol Museum, including USS Arizona artifacts. Monuments and memorials fill Wesley Bolin Plaza outside.
Casa Grande Ruins National Monument
Standing for more than 600 years, the Great House is the centerpiece of this preserved Ancestral Sonoran Desert People's farming community near Coolidge. Visitors can also see the adobe walls of Compound A and a visitor center museum.
Picacho Peak State Park
Between Tucson and Casa Grande off I-10, the park surrounds 1,500-foot Picacho Peak, site of the 1862 Battle of Picacho Pass. Expect hiking trails, a campground, and spring displays of Mexican gold poppies.
Tumacácori National Historical Park
An adobe mission church anchors this park in the Santa Cruz River valley, where O'odham, Yaqui, and Apache people met Jesuit and Franciscan missionaries. Tour the mission grounds and visitor center, then walk the Anza Trail along the river.
Mission San Cayetano de Calabazas
Part of Tumacácori National Historical Park, these adobe church ruins date to a Pima settlement established in 1756 and abandoned in 1786 after Apache raids. The site can only be visited on a reserved ranger-led tour.
When you get to Guaymas
Guaymas is a working port on Sonora's Gulf of California coast, where the desert mountains drop straight to the sea. Its old downtown keeps a cluster of historic churches and a waterfront plaza, and the resort area of San Carlos sits just up the coast.
- Templo de San Fernando: The church of San Fernando is one of the historic landmarks of downtown Guaymas. source
- Plaza 13 de Julio: This downtown plaza is one of the public squares highlighted by Mexico's Culture Ministry among Guaymas' points of interest. source
- Templo de San José de Guaymas: The parish church of San José is another stop on a walk through the city's historic churches, along with the Sagrado Corazón church. source
More drives to Guaymas
- Gilbert, AZ to Guaymas
- Goodyear, AZ to Guaymas
- Cottonwood, AZ to Guaymas
- Clarkdale, AZ to Guaymas
- Sierra Vista, AZ to Guaymas
- Tucson, AZ to Guaymas
From Sedona to other places in Mexico
- Sedona, AZ to Rosarito
- Sedona, AZ to Sonoyta
- Sedona, AZ to Tecate
- Sedona, AZ to Hermosillo
- Sedona, AZ to Nogales
- Sedona, AZ to Tijuana
All routes to Guaymas, border crossings and permits in one place: Driving to Guaymas, Mexico from the U.S.
Continue Your Adventure
Frequently asked questions
How long is the drive from Sedona to Guaymas?
About 9 h 16 min of driving without stops, over 554 miles.
How far is Guaymas from Sedona by car?
About 554 miles (891 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Sedona to Guaymas drive cross into Mexico?
At about mile 294 of this route, from Arizona into Sonora, near the Nogales port of entry.
Do I need a permit to drive my car from Sedona to Guaymas?
No vehicle permit is needed. Guaymas is inside Sonora's free zone (west of Highway 15 as far south as Empalme, plus a strip along the border that includes Cananea). Going farther south or east of Highway 15 requires a permit. You also need Mexican auto insurance and a passport book or card. An FMM entry permit is required too.
Is it safe to drive from Sedona to Guaymas?
The U.S. State Department rates Sonora Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Sedona to Guaymas use?
In order: AZ 179, I-17, I-10, I-19, MEX-15D and MEX-15. The road-by-road table above shows the route miles and states for each one.
What are good stops between Sedona and Guaymas?
Closest to the road: Montezuma Castle National Monument (National monument, mile 23, 0.6 mi from the route); Cathedral of Saints Simon and Jude (catholic cathedral, mile 108, 0.2 mi from the route); Tumacácori National Historical Park (National Historical Park, mile 274, 0.2 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.