São Vicente to Três Lagoas is about 453 road miles (729 km): roughly 8 h 50 min at the wheel if you don't stop.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Road maintenance is inadequate in many areas.”
| Distance by road | 453 mi (729 km) |
|---|---|
| Driving time, no stops | 8 h 50 min |
| Main roads, in order | SP-160 → SP-015 → SP-280 → SP-209 → SP-300 → BR-262 |
| States on the route | São Paulo, Mato Grosso do Sul |
| Fuel estimate (car at 25 mpg) | about 18.1 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
How the São Vicente to Três Lagoas drive plays out
SP-300 (255 mi) and SP-280 (123 mi) carry about 83% of the 453 miles. It runs through 2 states: São Paulo, Mato Grosso do Sul. Of the 8 stops listed below, 3 are within a mile of the road.
Which roads connect São Vicente and Três Lagoas
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | São Paulo |
| SP-160 | 1–37 | 36 | São Paulo |
| local roads | 37–42 | 5 | São Paulo |
| SP-015 | 42–48 | 6 | São Paulo |
| SP-280 | 48–171 | 123 | São Paulo |
| SP-209 | 171–183 | 12 | São Paulo |
| connecting roads | 183–185 | 2 | São Paulo |
| SP-300 | 185–239 | 54 | São Paulo |
| local roads | 239–243 | 4 | São Paulo |
| SP-300 | 243–444 | 201 | São Paulo |
| BR-262 | 444–449 | 5 | São Paulo, Mato Grosso do Sul |
| local roads | 449–453 | 4 | Mato Grosso do Sul |
- Mile 447 of this route: São Paulo → Mato Grosso do Sul (state line)
What to see on the way from São Vicente to Três Lagoas
- Right off the route (under 1 mile): Instituto Tomie Ohtake (mile 45), Dimitri Sensaud de Lavaud Museum (mile 51), Thermas Acqualinda (mile 427)
- Museums and history: São Paulo Museum of Modern Art (mile 41), Instituto Tomie Ohtake (mile 45), Dimitri Sensaud de Lavaud Museum (mile 51), Museu Histórico Municipal de Bauru (mile 242)
- With kids: Simba Safari (mile 35), São Paulo Aquarium (mile 37), Thermas Acqualinda (mile 427)
Simba Safari
At Simba Safari, a zoo in São Paulo's Cursino district, visitors ride park vehicles along a route of about 2.9 km through roughly 80,000 square meters to see the animals.
São Paulo Aquarium
The São Paulo Aquarium is an oceanarium in the Ipiranga district of São Paulo, opened in July 2006 as the first themed aquarium in Latin America.
Teatro Paulo Eiró
Teatro Paulo Eiró is a public theater in Santo Amaro, south São Paulo, with 467 seats, presenting music, dance and theater, and home to the Santo Amaro Philharmonic Orchestra.
São Paulo Museum of Modern Art
Set inside Ibirapuera Park, the São Paulo Museum of Modern Art was founded by Francisco Matarazzo Sobrinho and Yolanda Penteado in 1948 and modeled on New York's Museum of Modern Art.
Instituto Tomie Ohtake
Opened in November 2001, the Instituto Tomie Ohtake occupies a building designed by architect Ruy Ohtake, Tomie's son; his brother Ricardo Ohtake founded the institute.
Dimitri Sensaud de Lavaud Museum
Also called the Osasco Museum, the Dimitri Sensaud de Lavaud Museum occupies a 19th-century mansion built by Antônio Agú for banker Giovanni Brícola in Osasco, Greater São Paulo.
Museu Histórico Municipal de Bauru
Photos, newspapers, documents, furniture, machines and tools tied to the city's past fill the Museu Histórico Municipal de Bauru, which tells the history of Bauru.
Thermas Acqualinda
Thermas Acqualinda is a themed thermal water park in Andradina, São Paulo state, built by politician and businessman Mário Celso Lopes as a leisure complex.
Arriving in Três Lagoas
Lagoa Maior
Lagoa Maior is the main of the three urban lagoons that give Três Lagoas, in Mato Grosso do Sul, its name; it spans about 418,000 square meters and is under three meters deep.
More drives to Três Lagoas
- Botucatu to Três Lagoas
- Ribeirão Preto to Três Lagoas
- Campinas to Três Lagoas
- Poços de Caldas to Três Lagoas
- Cascavel to Três Lagoas
- São Paulo to Três Lagoas
From São Vicente to other places in Brazil
- São Vicente to Paranapiacaba
- São Vicente to Bragança Paulista
- São Vicente to Itu
- São Vicente to Limeira
- São Vicente to Mogi Guaçu
- São Vicente to Botucatu
Frequently asked questions
How long does it take to drive from São Vicente to Três Lagoas?
About 8 h 50 min of driving without stops, over 453 miles.
What is the driving distance from São Vicente to Três Lagoas?
About 453 miles (729 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the São Vicente to Três Lagoas drive?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from São Vicente to Três Lagoas?
In order: SP-160, SP-015, SP-280, SP-209, SP-300 and BR-262. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from São Vicente to Três Lagoas?
Closest to the road: Instituto Tomie Ohtake (museum, mile 45, 0.6 mi from the route); Dimitri Sensaud de Lavaud Museum (museum, mile 51, 0.9 mi from the route); Thermas Acqualinda (water park, mile 427, 0.2 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.