Santos to Presidente Prudente is about 389 road miles (626 km): roughly 7 h 20 min at the wheel if you don't stop.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Road maintenance is inadequate in many areas.”
| Total distance | 389 mi (626 km) |
|---|---|
| Drive time without stops | 7 h 20 min |
| Main roads, in order | SP-160 → SP-015 → SP-280 → SP-225 → SP-327 → SP-270 |
| States on the route | São Paulo |
| Fuel estimate (car at 25 mpg) | about 15.6 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
On the road from Santos to Presidente Prudente
SP-280 (188 mi) and SP-270 (114 mi) carry about 78% of the 389 miles. Of the 9 stops listed below, 3 are within a mile of the road.
Road-by-road breakdown: Santos to Presidente Prudente
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–6 | 6 | São Paulo |
| SP-160 | 6–41 | 35 | São Paulo |
| local roads | 41–47 | 6 | São Paulo |
| SP-015 | 47–53 | 6 | São Paulo |
| SP-280 | 53–241 | 188 | São Paulo |
| SP-225 | 241–253 | 12 | São Paulo |
| SP-327 | 253–273 | 20 | São Paulo |
| SP-270 | 273–387 | 114 | São Paulo |
| local roads | 387–389 | 2 | São Paulo |
Breaking up the drive: stops between Santos and Presidente Prudente
- Right off the route (under 1 mile): Botanical Museum Dr. João Barbosa Rodrigues (mile 41), Museu da Lâmpada (mile 43), Civil Police Museum of the State of São Paulo (mile 50)
- Nature and outdoors: Jaraguá State Park (mile 56), Parque Geológico do Varvito (mile 96)
- Museums and history: Botanical Museum Dr. João Barbosa Rodrigues (mile 41), Museu da Lâmpada (mile 43), Professor Aristóteles Orsini Planetarium (mile 46), Civil Police Museum of the State of São Paulo (mile 50), Estação de Assis (mile 313)
- With kids: Cidade da Criança (mile 36)
Cidade da Criança
Opened on October 10, 1968, Cidade da Criança in São Bernardo do Campo was the first theme park in Brazil and Latin America and sits behind the former Vera Cruz Film Studios.
Botanical Museum Dr. João Barbosa Rodrigues
Part of São Paulo's Instituto de Botânica, the Botanical Museum Dr. João Barbosa Rodrigues is a public state museum that works as an educational exhibition space.
Museu da Lâmpada
Opened in São Paulo on April 15, 2012, Museu da Lâmpada traces the history of lighting and the lamp back to prehistoric times, using items collected by the electrical supplier GIMAWA.
Professor Aristóteles Orsini Planetarium
Inside Ibirapuera Park in São Paulo, the Professor Aristóteles Orsini Planetarium, also called the Ibirapuera Planetarium, opened in January 1957 as the first planetarium in Brazil and Latin America.
Teatro Procópio Ferreira
Teatro Procópio Ferreira is a theater in São Paulo, Brazil, where audiences can catch live stage shows.
Civil Police Museum of the State of São Paulo
Also known as the Crime Museum, the Civil Police Museum in São Paulo's University City, Butantã, preserves police investigation records, weapons, jailhouse tattoos and objects used in crimes.
Jaraguá State Park
A former gold-era farm turned state park in 1961, Jaraguá State Park guards one of the last Atlantic Forest remnants in greater São Paulo, with trails around 1,135-meter Jaraguá Peak.
Parque Geológico do Varvito
Banded rock walls line a former quarry in Itu, where Parque Geológico do Varvito shows off varvite, sediment that settled in glacial lakes some 280 million years ago.
Estação de Assis
Assis's railway station joined the company's trunk line in 1914 and got its current building in 1926; the original station was adapted as housing for traffic staff in 1927.
In Presidente Prudente itself
Teatro Municipal Procópio Ferreira
Named after actor Procópio Ferreira, this municipal theater in Presidente Prudente, São Paulo state, is the city's most-used public venue.
More drives to Presidente Prudente
- Araraquara to Presidente Prudente
- Limeira to Presidente Prudente
- Campinas to Presidente Prudente
- Jundiaí to Presidente Prudente
- Mogi das Cruzes to Presidente Prudente
- São Vicente to Presidente Prudente
From Santos to other places in Brazil
- Santos to Itanhaém
- Santos to Bragança Paulista
- Santos to Itu
- Santos to Limeira
- Santos to Mogi Guaçu
- Santos to Botucatu
Frequently asked questions
How long is the drive from Santos to Presidente Prudente?
About 7 h 20 min of driving without stops, over 389 miles.
What is the driving distance from Santos to Presidente Prudente?
About 389 miles (626 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Santos to Presidente Prudente?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from Santos to Presidente Prudente?
In order: SP-160, SP-015, SP-280, SP-225, SP-327 and SP-270. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Santos to Presidente Prudente?
Closest to the road: Botanical Museum Dr. João Barbosa Rodrigues (museum, mile 41, 0.4 mi from the route); Museu da Lâmpada (museum, mile 43, 0.9 mi from the route); Civil Police Museum of the State of São Paulo (police museum, mile 50, 0.6 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.