The Wayro route from Santos to Cachoeiro de Itapemirim is 507 miles (816 km), about 12 h 19 min of driving without stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Flooding makes some roads through the Amazon impassable for much of the year.”
| Distance | 507 mi (816 km) |
|---|---|
| Driving time, no stops | 12 h 19 min |
| Main roads, in order | SP-150 → SP-021 → SP-070 → SP-060 → BR-116 → BR-393 → CMG-393 → RJ-186 → ES-297 → BR-101 → ES-496 |
| States on the route | São Paulo, Rio de Janeiro, Minas Gerais, Espírito Santo |
| Fuel estimate (car at 25 mpg) | about 20.3 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
What the drive from Santos to Cachoeiro de Itapemirim is like
SP-060 (103 mi) and BR-393 (78 mi) carry about 36% of the 507 miles. It runs through 4 states: São Paulo, Rio de Janeiro, Minas Gerais, Espírito Santo. Of the 9 stops listed below, 5 are within a mile of the road.
Road-by-road breakdown: Santos to Cachoeiro de Itapemirim
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–4 | 4 | São Paulo |
| SP-150 | 4–27 | 23 | São Paulo |
| connecting roads | 27–30 | 3 | São Paulo |
| SP-021 | 30–59 | 29 | São Paulo |
| connecting roads | 59–60 | 1 | São Paulo |
| SP-070 | 60–116 | 56 | São Paulo |
| connecting roads | 116–119 | 3 | São Paulo |
| SP-060 | 119–222 | 103 | São Paulo, Rio de Janeiro |
| BR-116 | 222–229 | 7 | Rio de Janeiro |
| connecting roads | 229–230 | 1 | Rio de Janeiro |
| local roads | 230–234 | 4 | Rio de Janeiro |
| BR-393 | 234–306 | 72 | Rio de Janeiro |
| local roads | 306–311 | 5 | Rio de Janeiro |
| connecting roads | 311–312 | 1 | Rio de Janeiro |
| BR-393 | 312–318 | 6 | Rio de Janeiro |
| local roads | 318–351 | 33 | Rio de Janeiro |
| connecting roads | 351–352 | 1 | Rio de Janeiro |
| CMG-393 | 352–380 | 28 | Minas Gerais |
| connecting roads | 380–381 | 1 | Minas Gerais |
| RJ-186 | 381–444 | 63 | Minas Gerais, Rio de Janeiro |
| connecting roads | 444–445 | 1 | Rio de Janeiro |
| ES-297 | 445–473 | 28 | Rio de Janeiro, Espírito Santo |
| BR-101 | 473–500 | 27 | Espírito Santo |
| ES-496 | 500–504 | 4 | Espírito Santo |
| local roads | 504–507 | 3 | Espírito Santo |
- Mile 191 of this route: São Paulo → Rio de Janeiro (state line)
- Mile 352 of this route: Rio de Janeiro → Minas Gerais (state line)
- Mile 386 of this route: Minas Gerais → Rio de Janeiro (state line)
- Mile 470 of this route: Rio de Janeiro → Espírito Santo (state line)
Stops between Santos and Cachoeiro de Itapemirim
- Right off the route (under 1 mile): Basilica of Our Lady of Aparecida (mile 147), Itatiaia National Park (mile 201), Santana Cathedral (mile 257), Fazenda São João da Prosperidade (mile 258), Fazenda São Luiz da Boa Sorte (mile 284)
- Nature and outdoors: Itatiaia National Park (mile 201), Serra da Concórdia State Park (mile 270), Serra das Torres Natural Monument (mile 487)
- Museums and history: Calçada do Lorena (mile 12), Anthropology Museum of the Paraíba Valley (mile 86), Basilica of Our Lady of Aparecida (mile 147), Santana Cathedral (mile 257), Fazenda São João da Prosperidade (mile 258), Fazenda São Luiz da Boa Sorte (mile 284), Serra das Torres Natural Monument (mile 487)
Calçada do Lorena
Calçada do Lorena, in the Serra do Mar of São Paulo state, was the first paved road linking São Paulo to Santos, built on the orders of governor Bernardo José Maria de Lorena.
Anthropology Museum of the Paraíba Valley
Housed in an 1857 mansion in Jacareí, the Anthropology Museum of the Paraíba Valley (Museu de Antropologia do Vale do Paraíba) shows sacred and folk art, paintings, and archaeological finds such as ceramic vessels and stone tools.
Basilica of Our Lady of Aparecida
Brazil's National Shrine in Aparecida houses the image of Our Lady Aparecida that fishermen pulled from the Paraíba do Sul River in 1717. Work on the current basilica began in 1955, and Pope John Paul II consecrated it in 1980.
Itatiaia National Park
Brazil's national park system started here: Itatiaia National Park (Parque Nacional do Itatiaia) was created in 1937 as the country's first. The protected area lies on the border between Rio de Janeiro and Minas Gerais states.
Santana Cathedral
Dedicated to St. Anne, this cathedral in Barra do Piraí is the seat of the Diocese of Barra do Piraí–Volta Redonda; Emperor Pedro II attended the laying of its cornerstone during a visit to the parish.
Fazenda São João da Prosperidade
Fazenda São João da Prosperidade is a historic rural estate in Barra do Piraí, Rio de Janeiro state, founded in the 19th century by Antônio Gonçalves de Morais.
Serra da Concórdia State Park
Serra da Concórdia State Park (Parque Estadual da Serra da Concórdia) is a state park in Rio de Janeiro state that protects an area of Atlantic Forest.
Fazenda São Luiz da Boa Sorte
Dating from the coffee era in Rio de Janeiro state's Paraíba Valley, Fazenda São Luiz da Boa Sorte is a historic estate listed by the state heritage institute.
Serra das Torres Natural Monument
Covering about 10,459 hectares of Atlantic Forest in Atílio Vivácqua, Mimoso do Sul and Muqui, the Serra das Torres Natural Monument was created in 2010 to protect the peaks of a mountain range in southern Espírito Santo.
In Cachoeiro de Itapemirim itself
Itabira Natural Monument
Itabira Natural Monument is a protected area in the state of Espírito Santo, Brazil, listed in the natural monument category.
Casa de Cultura Roberto Carlos
In Cachoeiro de Itapemirim, Espírito Santo, the Casa de Cultura Roberto Carlos is the house where singer Roberto Carlos was born and lived with his family until age thirteen.
Teatro Municipal Rubem Braga
Opened by the city of Cachoeiro de Itapemirim on April 28, 2000, the Teatro Municipal Rubem Braga seats 292 and hosts plays, dance, concerts and films.
More drives to Cachoeiro de Itapemirim
- Juiz de Fora to Cachoeiro de Itapemirim
- Ipatinga to Cachoeiro de Itapemirim
- Niterói to Cachoeiro de Itapemirim
- Sete Lagoas to Cachoeiro de Itapemirim
- Angra dos Reis to Cachoeiro de Itapemirim
- Divinópolis to Cachoeiro de Itapemirim
From Santos to other places in Brazil
- Santos to Itanhaém
- Santos to Bragança Paulista
- Santos to Itu
- Santos to Limeira
- Santos to Mogi Guaçu
- Santos to Botucatu
Frequently asked questions
How long does it take to drive from Santos to Cachoeiro de Itapemirim?
About 12 h 19 min of driving without stops, over 507 miles.
How far is Cachoeiro de Itapemirim from Santos by car?
About 507 miles (816 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Santos to Cachoeiro de Itapemirim?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from Santos to Cachoeiro de Itapemirim?
In order: SP-150, SP-021, SP-070, SP-060, BR-116, BR-393, CMG-393, RJ-186, ES-297, BR-101 and ES-496. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Santos to Cachoeiro de Itapemirim?
Closest to the road: Basilica of Our Lady of Aparecida (basilica, mile 147, 0.4 mi from the route); Itatiaia National Park (national park, mile 201, 0.3 mi from the route); Fazenda São Luiz da Boa Sorte (historic estate, mile 284, 0.3 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.