By road, Salto and Pergamino, Argentina are about 336 miles (541 km) apart, or roughly 6 h 8 min of driving. You cross from Uruguay into Argentina at about mile 10, at Concordia–Salto.
Full advisory: Uruguay, Argentina. Advisory issued: Uruguay July 28, 2026; Argentina July 10, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Uruguay: “Several of the main highways are particularly accident-ridden.”
- Argentina: “Drivers in Argentina tend to be aggressive, especially in Buenos Aires, and often ignore traffic regulations.”
| Total distance | 336 mi (541 km) |
|---|---|
| Drive time without stops | 6 h 8 min |
| Main roads, in order | RNA015 → RN14 → RN12 → RN193 → RN8 |
| Border crossing | about mile 10, Uruguay → Argentina (Concordia–Salto) |
| Regions on the route | Salto, Entre Ríos, Buenos Aires |
| Fuel estimate (car at 25 mpg) | about 13.5 gal; actual use varies by vehicle and traffic |
| Stops listed below | 4 |
Border crossing: what to bring for Argentina
The route crosses at about mile 10, at Concordia–Salto, from Salto into Entre Ríos. Plan on two checks on each side: immigration for your passport and customs for the car.
| Entering Argentina (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. |
|---|---|
| Driving in Argentina | A valid U.S. license usually works; an International Driving Permit is recommended. |
| Entering Uruguay (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. |
| Driving in Uruguay | You can drive on your U.S. license. |
| The car, entering Argentina | Argentine customs (ARCA) registers the car's temporary entry. Bring the title or registration, liability insurance valid in Argentina and, if you don't own the car, a power of attorney signed before a notary. A rental car needs the rental company's MERCOSUR circulation authorization (ACM), and the company must be registered with Argentine customs. |
| Rental car | Cross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book. |
Sources: U.S. State Department, Argentina (updated July 16, 2026); U.S. State Department, Uruguay (updated August 13, 2026); ARCA (Argentine customs). Checked October 10, 2026; rules change, so confirm before you go.
How the Salto to Pergamino drive plays out
RN14 (166 mi) and RN8 (76 mi) carry about 72% of the 336 miles. The first 10 miles are in Uruguay; the last 326 are in Argentina. It runs through 3 regions: Salto, Entre Ríos, Buenos Aires. Of the 4 stops listed below, 3 are within a mile of the road.
Roads you'll take from Salto to Pergamino
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–10 | 10 | Salto |
| RNA015 | 10–21 | 11 | Entre Ríos |
| RN14 | 21–187 | 166 | Entre Ríos |
| RN12 | 187–237 | 50 | Entre Ríos, Buenos Aires |
| RN193 | 237–256 | 19 | Buenos Aires |
| connecting roads | 256–257 | 1 | Buenos Aires |
| RN8 | 257–333 | 76 | Buenos Aires |
| local roads | 333–336 | 3 | Buenos Aires |
- Mile 10 of this route: Salto → Entre Ríos (international border)
- Mile 218 of this route: Entre Ríos → Buenos Aires (region line)
Breaking up the drive: stops between Salto and Pergamino
- Right off the route (under 1 mile): Termas de Salto Grande (mile 9), El Palmar National Park (mile 64), Parque Criollo y Museo Gauchesco Ricardo Gu͏̈iraldes (mile 268)
- Nature and outdoors: Termas de Salto Grande (mile 9), El Palmar National Park (mile 64), Ciervo de los Pantanos National Park (mile 234)
- Museums and history: Parque Criollo y Museo Gauchesco Ricardo Gu͏̈iraldes (mile 268)
Termas de Salto Grande
On the Uruguayan shore of the Salto Grande dam's lake in Salto department, Termas de Salto Grande is a hot spring complex.
El Palmar National Park
Set off National Route 14 in Entre Ríos, between Colón and Concordia, El Palmar National Park protects groves of yatay palms along with gallery forest, savanna and grassland.
Ciervo de los Pantanos National Park
About 2,500 hectares of wetlands in Campana, Buenos Aires province, are protected as Ciervo de los Pantanos National Park. It's a Ramsar Site and home to the marsh deer and plenty of waterbirds.
Parque Criollo y Museo Gauchesco Ricardo Gu͏̈iraldes
In San Antonio de Areco, Buenos Aires province, the Museo Gauchesco Ricardo Güiraldes spreads ten exhibit rooms across the 97-hectare Parque Criollo, opened in 1938, and presents Argentina's past, especially that of Buenos Aires province.
More drives to Pergamino
- Buenos Aires to Pergamino
- La Plata to Pergamino
- Mar del Plata to Pergamino
- Paraná to Pergamino
- Corrientes to Pergamino
- Resistencia to Pergamino
More drives from Salto
- Salto to Mercedes, Uruguay
- Salto to Carmelo
- Salto to Colonia del Sacramento
- Salto to Nueva Helvecia
- Salto to Veinticinco de Agosto
- Salto to Fray Marcos
Frequently asked questions
How long does it take to drive from Salto to Pergamino, Argentina?
About 6 h 8 min of driving without stops, over 336 miles.
How far is Pergamino, Argentina from Salto by car?
About 336 miles (541 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Salto to Pergamino drive cross the border?
At about mile 10, from Uruguay into Argentina, at Concordia–Salto.
What do U.S. citizens need to drive from Salto into Argentina?
No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. A valid U.S. license usually works; an International Driving Permit is recommended. (U.S. State Department, updated July 16, 2026.)
What does the U.S. travel advisory say about the Salto to Pergamino drive?
The U.S. State Department rates Uruguay Level 2: Exercise Increased Caution; Argentina Level 1: Exercise Normal Precautions. Read the full advisory before you go.
What roads does the drive from Salto to Pergamino use?
In order: RNA015, RN14, RN12, RN193 and RN8. The road-by-road table above shows the route miles for each one.
What are good stops between Salto and Pergamino?
Closest to the road: Termas de Salto Grande (hot spring, mile 9, 0.7 mi from the route); El Palmar National Park (national park of Argentina, mile 64, 0.1 mi from the route); Parque Criollo y Museo Gauchesco Ricardo Gu͏̈iraldes (museum, mile 268, 0.6 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.