By road, Salto and Veinticinco de Agosto are about 267 miles (429 km) apart, or roughly 5 h 33 min of driving.
Full advisory: Uruguay. Advisory issued: Uruguay July 28, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Uruguay: “If you are in an accident involving injury, stay in place until a police officer arrives.”
| Total distance | 267 mi (429 km) |
|---|---|
| Time at the wheel, no stops | 5 h 33 min |
| Departments on the route | Salto, Paysandú, Río Negro, Flores, San José, Florida |
| Fuel estimate (car at 25 mpg) | about 10.7 gal; actual use varies by vehicle and traffic |
| Stops listed below | 4 |
The Salto–Veinticinco de Agosto drive in a few lines
It runs through 6 departments: Salto, Paysandú, Río Negro, Flores, San José, Florida. Of the 4 stops listed below, 2 are within a mile of the road.
Salto to Veinticinco de Agosto: the road sequence
| Road | Route miles (from–to) | Length, mi | Department |
|---|---|---|---|
| local roads | 0–267 | 267 | Salto, Paysandú, Río Negro, Flores, San José |
- Mile 8 of this route: Salto → Paysandú (department line)
- Mile 99 of this route: Paysandú → Río Negro (department line)
- Mile 154 of this route: Río Negro → Flores (department line)
- Mile 215 of this route: Flores → San José (department line)
- Mile 267 of this route: San José → Florida (department line)
Stops between Salto and Veinticinco de Agosto
- Right off the route (under 1 mile): Termas del Guaviyú (mile 35), Reserva de Flora y fauna Dr. Rodolfo Tálice (mile 183)
- Nature and outdoors: Termas del Guaviyú (mile 35), Reserva de Flora y fauna Dr. Rodolfo Tálice (mile 183)
- Museums and history: Nuestra Señora del Rosario y San Benito de Palermo, Paysandú (mile 73), Cathedral of San José de Mayo (mile 245)
Termas del Guaviyú
Next to Guaviyú Creek at kilometer 432 of Route 3 in Paysandú department, Termas del Guaviyú is a hot spring complex in northwestern Uruguay.
Nuestra Señora del Rosario y San Benito de Palermo, Paysandú
Paysandú's Catholic parish church of Our Lady of the Rosary and St. Benedict of Palermo was named a minor basilica in 1949 and remains an active parish of the city.
Reserva de Flora y fauna Dr. Rodolfo Tálice
Off Route 3 near Trinidad, the Dr. Rodolfo Tálice Ecopark (Reserva de Flora y Fauna Dr. Rodolfo Talice) is a fenced wildlife reserve where axis deer, greater rheas and pampas deer roam free alongside other species.
Cathedral of San José de Mayo
The main Catholic church of San José de Mayo, the Cathedral Basilica of St. Joseph has been the diocesan seat since 1955, a minor basilica since 1957 and Uruguay's national shrine of Saint Joseph.
More drives to Veinticinco de Agosto
- Colonia del Sacramento to Veinticinco de Agosto
- Carmelo to Veinticinco de Agosto
- Paysandú to Veinticinco de Agosto
- Tacuarembó to Veinticinco de Agosto
- Rivera to Veinticinco de Agosto
- Artigas to Veinticinco de Agosto
From Salto to other places in Uruguay
- Salto to Mercedes, Uruguay
- Salto to Carmelo
- Salto to Colonia del Sacramento
- Salto to Nueva Helvecia
- Salto to Fray Marcos
- Salto to Minas
Frequently asked questions
How long does it take to drive from Salto to Veinticinco de Agosto?
About 5 h 33 min of driving without stops, over 267 miles.
How far is Veinticinco de Agosto from Salto by car?
About 267 miles (429 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Salto to Veinticinco de Agosto?
The U.S. State Department rates Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.
What are good stops between Salto and Veinticinco de Agosto?
Closest to the road: Termas del Guaviyú (hot spring, mile 35, 0.6 mi from the route); Nuestra Señora del Rosario y San Benito de Palermo, Paysandú (basilica, mile 73, 2 mi from the route); Reserva de Flora y fauna Dr. Rodolfo Tálice (botanical garden, mile 183, 0.3 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.