Salina Cruz to Zacatlán Road Trip: Route, Tolls & Stops

By admin, 13 October, 2026

By road, Salina Cruz and Zacatlán are about 433 miles (697 km) apart, or roughly 8 h 49 min of driving.

U.S. State Department travel advisory: Oaxaca — Level 2, Exercise Increased Caution; Puebla — Level 2, Exercise Increased Caution; Tlaxcala — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Puebla is the Mexican state that contains Zacatlán. See the full advisory for current details.
GuiengolaMitlaYagulEl PalmilloDainzúTehuacán-Cuicatlán Biosphere ReserveMuseo del Valle de TehuacánMuseo Taurino de HuamantlaSantuario de Nuestro Padre Jesús de AquixtlaSalina CruzZacatlán
Route from Salina Cruz to Zacatlán with the 9 stops listed below (blue dots).
Distance433 mi (697 km)
Drive time without stops8 h 49 min
Main roads, in orderMEX-185 → MEX-190 → MEX-135D → MEX-136 → MEX-119
Mexican states on the routeOaxaca, Puebla, Tlaxcala
Toll roads (as marked in OpenStreetMap)MEX-135D, MEX-150D
Fuel estimate (car at 25 mpg)about 17.3 gal; actual use varies by vehicle and traffic
Stops listed below9

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Salina Cruz to Zacatlán is like

MEX-190 (161 mi) and MEX-135D (151 mi) carry about 72% of the 433 miles. It runs through 3 states: Oaxaca, Puebla, Tlaxcala. OpenStreetMap marks tolled sections on MEX-135D and MEX-150D. Of the 9 stops listed below, 5 are within a mile of the road.

Roads you'll take from Salina Cruz to Zacatlán

RoadRoute miles (from–to)Length, miState
MEX-1850–1111Oaxaca
MEX-19011–172161Oaxaca
MEX-135D172–323151Oaxaca, Puebla
connecting roads323–3241Puebla
local roads324–36440Puebla
MEX-136364–38824Tlaxcala
connecting roads388–3913Tlaxcala
MEX-119391–43342Tlaxcala, Puebla
  • Mile 272 of this route: Oaxaca → Puebla (state line)
  • Mile 364 of this route: Puebla → Tlaxcala (state line)
  • Mile 409 of this route: Tlaxcala → Puebla (state line)

Places worth a stop between Salina Cruz and Zacatlán

  • Right off the route (under 1 mile): Mitla (mile 140), Yagul (mile 145), El Palmillo (mile 146), Dainzú (mile 153), Museo Taurino de Huamantla (mile 373)
  • Nature and outdoors: Tehuacán-Cuicatlán Biosphere Reserve (mile 280)
  • Museums and history: Guiengola (mile 18), Mitla (mile 140), Yagul (mile 145), El Palmillo (mile 146), Dainzú (mile 153), Museo del Valle de Tehuacán (mile 295), Museo Taurino de Huamantla (mile 373)

Guiengola

Mile 18 · Archaeological site · 2 mi from the route · side trip; actual detour depends on access roads

Guiengola is a Late Postclassic Zapotec archaeological site near Santo Domingo Tehuantepec, on high ground above the Tehuantepec River and known as a fortified settlement.

Mitla

Mile 140 · Archaeological site · 0.2 mi from the route

Mitla, the key site of Zapotec culture and Oaxaca's second major archaeological site after Monte Albán, lies 44 km from Oaxaca City at the upper end of the Tlacolula Valley.

Yagul

Mile 145 · Archaeological site · 0.9 mi from the route

On a rocky hill in Oaxaca's Tlacolula Valley, Yagul is a Zapotec site whose builders linked platforms by paths. Explore the Palace of the Six Patios, a ball court, tombs and a fortress wall with lookouts.

El Palmillo

Mile 146 · Archaeological site · 0.2 mi from the route

On a hilltop in the eastern Tlacolula arm of the Valley of Oaxaca, El Palmillo is a Classic Period Zapotec archaeological site just south of Mitla and east of Monte Albán.

Dainzú

Mile 153 · Archaeological site · 0.7 mi from the route

About 20 km southeast of Oaxaca city, Dainzú is a Zapotec archaeological site, an ancient village that developed earlier than nearby Monte Albán and Mitla and was later contemporary with them.

Tehuacán-Cuicatlán Biosphere Reserve

Mile 280 · Biosphere reserve · 7 mi from the route · side trip; actual detour depends on access roads

Cactus diversity reaches one of its peaks in the Tehuacán-Cuicatlán Valley, a dry landscape shared by Puebla and Oaxaca. Ancient canals, wells, terraces and dams show how people managed its scarce water.

Museo del Valle de Tehuacán

Mile 295 · Museum · 3 mi from the route · side trip; actual detour depends on access roads

Tehuacán's 18th-century former Carmelite convent has housed the Valley of Tehuacán Museum since 2002. Exhibits trace the history of corn and its ties to the valley's early peoples.

Museo Taurino de Huamantla

Mile 373 · Bullfighting museum · 0.7 mi from the route

Next to Huamantla's La Taurina bullring, the Museo Taurino occupies an 18th-century building and since 1982 has displayed bullfighters' costumes, vintage posters, scale models of Mexican bullrings and murals about the Huamantlada.

Santuario de Nuestro Padre Jesús de Aquixtla

Mile 421 · Sanctuary · 1 mi from the route

In the Sierra Norte de Puebla, the sanctuary of Nuestro Padre Jesús in Aquixtla draws thousands of pilgrims during the year who come to give thanks for favors received.

More drives to Zacatlán

From Salina Cruz to other places in Mexico

Frequently asked questions

How long is the drive from Salina Cruz to Zacatlán?

About 8 h 49 min of driving without stops, over 433 miles.

How far is Zacatlán from Salina Cruz by car?

About 433 miles (697 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Salina Cruz to Zacatlán?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Salina Cruz to Zacatlán?

The U.S. State Department rates Oaxaca Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

Which highways go from Salina Cruz to Zacatlán?

In order: MEX-185, MEX-190, MEX-135D, MEX-136 and MEX-119. The road-by-road table above shows the route miles for each one.

Where can you stop on the way from Salina Cruz to Zacatlán?

Closest to the road: Mitla (archaeological site, mile 140, 0.2 mi from the route); El Palmillo (archaeological site, mile 146, 0.2 mi from the route); Dainzú (archaeological site, mile 153, 0.7 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.