Salina Cruz to Actopan Road Trip: Route, Stops & Safety

By admin, 13 October, 2026

Plan on about 9 h 19 min of driving for the 481-mile (774 km) trip from Salina Cruz to Actopan, before any stops.

U.S. State Department travel advisory: Oaxaca — Level 2, Exercise Increased Caution; Puebla — Level 2, Exercise Increased Caution; Tlaxcala — Level 2, Exercise Increased Caution; Hidalgo — Level 2, Exercise Increased Caution; State of Mexico — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Hidalgo is the Mexican state that contains Actopan. See the full advisory for current details.
GuiengolaYagulLambityecoOaxaca Ethnobotanical GardenGraphic Arts Institute of OaxacaTehuacán-Cuicatlán Biosphere ReserveFort GuadalupeLa Constancia MexicanaBioparque de Convivencia en Pachuca, HidalgoSalina CruzActopan
Route from Salina Cruz to Actopan with the 9 stops listed below (blue dots).
Total distance481 mi (774 km)
Time at the wheel, no stops9 h 19 min
Main roads, in orderMEX-185 → MEX-190 → MEX-135D → MEX-150D → MEX-M40D → MEX-132 → MEX-88
Mexican states on the routeOaxaca, Puebla, Tlaxcala, Hidalgo, State of Mexico
Toll roads (as marked in OpenStreetMap)MEX-135D, MEX-150D, MEX-M40D
Fuel estimate (car at 25 mpg)about 19.2 gal; actual use varies by vehicle and traffic
Stops listed below9

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

How the Salina Cruz to Actopan drive plays out

MEX-190 (161 mi) and MEX-135D (151 mi) carry about 65% of the 481 miles. It runs through 5 states: Oaxaca, Puebla, Tlaxcala, Hidalgo, State of Mexico. OpenStreetMap marks tolled sections on MEX-135D, MEX-150D and MEX-M40D. Of the 9 stops listed below, 5 are within a mile of the road.

The route from Salina Cruz to Actopan, road by road

RoadRoute miles (from–to)Length, miState
MEX-1850–1111Oaxaca
MEX-19011–172161Oaxaca
MEX-135D172–323151Oaxaca, Puebla
MEX-150D323–39269Puebla
connecting roads392–3931Puebla
MEX-M40D393–43845Puebla, Tlaxcala, Hidalgo, State of Mexico
MEX-132438–4424State of Mexico, Hidalgo
MEX-88442–45816Hidalgo
local roads458–48123Hidalgo
  • Mile 272 of this route: Oaxaca → Puebla (state line)
  • Mile 397 of this route: Puebla → Tlaxcala (state line)
  • Mile 420 of this route: Tlaxcala → Hidalgo (state line)
  • Mile 428 of this route: Hidalgo → State of Mexico (state line)
  • Mile 440 of this route: State of Mexico → Hidalgo (state line)

What to see on the way from Salina Cruz to Actopan

  • Right off the route (under 1 mile): Yagul (mile 145), Lambityeco (mile 148), Oaxaca Ethnobotanical Garden (mile 165), Graphic Arts Institute of Oaxaca (mile 165), La Constancia Mexicana (mile 375)
  • Nature and outdoors: Oaxaca Ethnobotanical Garden (mile 165), Tehuacán-Cuicatlán Biosphere Reserve (mile 280)
  • Museums and history: Guiengola (mile 18), Yagul (mile 145), Lambityeco (mile 148), Graphic Arts Institute of Oaxaca (mile 165), Fort Guadalupe (mile 372), La Constancia Mexicana (mile 375)
  • With kids: Bioparque de Convivencia en Pachuca, Hidalgo (mile 460)

Guiengola

Mile 18 · Archaeological site · 2 mi from the route · side trip; actual detour depends on access roads

Guiengola is a Late Postclassic Zapotec archaeological site near Santo Domingo Tehuantepec, on high ground above the Tehuantepec River and known as a fortified settlement.

Yagul

Mile 145 · Archaeological site · 0.9 mi from the route

On a rocky hill in Oaxaca's Tlacolula Valley, Yagul is a Zapotec site whose builders linked platforms by paths. Explore the Palace of the Six Patios, a ball court, tombs and a fortress wall with lookouts.

Lambityeco

Mile 148 · Archaeological site · 0.2 mi from the route

Lambityeco is a small Zapotec archaeological site just off Highway 190, about 3 km west of Tlacolula de Matamoros and roughly 25 km east of Oaxaca on the way to Mitla.

Oaxaca Ethnobotanical Garden

Mile 165 · Botanical garden · 0.4 mi from the route

Next to the Church of Santo Domingo in Oaxaca City, the Oaxaca Ethnobotanical Garden (Jardín Etnobotánico de Oaxaca) is a botanical garden covering about 2.3 acres.

Graphic Arts Institute of Oaxaca

Mile 165 · Art museum · 0.5 mi from the route

Founded by artist Francisco Toledo, the Graphic Arts Institute of Oaxaca is an art school in Oaxaca de Juárez that holds a large collection of Latin American artwork.

Tehuacán-Cuicatlán Biosphere Reserve

Mile 280 · Biosphere reserve · 7 mi from the route · side trip; actual detour depends on access roads

This arid valley straddling Puebla and Oaxaca joined UNESCO's World Heritage List in 2018 as a mixed site. It is a major center of cactus diversity and preserves ancient canals, wells, terraces and dams built to manage scarce water.

Fort Guadalupe

Mile 372 · Fort · 2 mi from the route · side trip; actual detour depends on access roads

Fort Guadalupe is a fort you'll find in the city of Puebla, within the Mexican state of the same name.

La Constancia Mexicana

Mile 375 · Museum · 0.4 mi from the route

A textile factory founded in 1835 in Puebla now houses the La Constancia museum complex, with a children's museum, a puppet house, a Mexican music museum, an automobile museum and a park of miniature world monuments.

Bioparque de Convivencia en Pachuca, Hidalgo

Mile 460 · Zoo · 2 mi from the route

Pachuca's Bioparque de Convivencia is a rescue and recovery center for wild, exotic and endemic animals saved from abuse, abandonment or risk, housing a wildlife rescue and rehabilitation unit.

More drives to Actopan

From Salina Cruz to other places in Mexico

Frequently asked questions

How long is the drive from Salina Cruz to Actopan?

About 9 h 19 min of driving without stops, over 481 miles.

How far is Actopan from Salina Cruz by car?

About 481 miles (774 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Salina Cruz to Actopan?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Salina Cruz to Actopan?

The U.S. State Department rates Oaxaca Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Salina Cruz to Actopan use?

In order: MEX-185, MEX-190, MEX-135D, MEX-150D, MEX-M40D, MEX-132 and MEX-88. The road-by-road table above shows the route miles for each one.

What are good stops between Salina Cruz and Actopan?

Closest to the road: Lambityeco (archaeological site, mile 148, 0.2 mi from the route); Oaxaca Ethnobotanical Garden (botanical garden, mile 165, 0.4 mi from the route); La Constancia Mexicana (museum, mile 375, 0.4 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.