Salina Cruz to Huejotzingo Road Trip: Route, Stops & Safety

By admin, 13 October, 2026

By road, Salina Cruz and Huejotzingo are about 392 miles (631 km) apart, or roughly 7 h 46 min of driving.

U.S. State Department travel advisory: Oaxaca — Level 2, Exercise Increased Caution; Puebla — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Puebla is the Mexican state that contains Huejotzingo. See the full advisory for current details.
GuiengolaMitlaYagulLambityecoMuseo del Ferrocarril Mexicano del SurSuchilquitongoTehuacán-Cuicatlán Biosphere ReserveCholulaSalina CruzHuejotzingo
Route from Salina Cruz to Huejotzingo with the 8 stops listed below (blue dots).
Total distance392 mi (631 km)
Time at the wheel, no stops7 h 46 min
Main roads, in orderMEX-185 → MEX-190 → MEX-135D → MEX-150D → MEX-150
Mexican states on the routeOaxaca, Puebla
Toll roads (as marked in OpenStreetMap)MEX-135D, MEX-150D
Fuel estimate (car at 25 mpg)about 15.7 gal; actual use varies by vehicle and traffic
Stops listed below8

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

The Salina Cruz–Huejotzingo drive in a few lines

MEX-190 (161 mi) and MEX-135D (151 mi) carry about 80% of the 392 miles. It runs through 2 states: Oaxaca, Puebla. OpenStreetMap marks tolled sections on MEX-135D and MEX-150D. Of the 8 stops listed below, 6 are within a mile of the road.

Road-by-road breakdown: Salina Cruz to Huejotzingo

RoadRoute miles (from–to)Length, miState
MEX-1850–1111Oaxaca
MEX-19011–172161Oaxaca
MEX-135D172–323151Oaxaca, Puebla
MEX-150D323–37249Puebla
local roads372–3775Puebla
connecting roads377–3825Puebla
MEX-150382–39210Puebla
  • Mile 272 of this route: Oaxaca → Puebla (state line)

Breaking up the drive: stops between Salina Cruz and Huejotzingo

  • Right off the route (under 1 mile): Mitla (mile 140), Yagul (mile 145), Lambityeco (mile 148), Museo del Ferrocarril Mexicano del Sur (mile 166), Suchilquitongo (mile 184), Cholula (mile 382)
  • Nature and outdoors: Tehuacán-Cuicatlán Biosphere Reserve (mile 280)
  • Museums and history: Guiengola (mile 18), Mitla (mile 140), Yagul (mile 145), Lambityeco (mile 148), Museo del Ferrocarril Mexicano del Sur (mile 166), Suchilquitongo (mile 184), Cholula (mile 382)

Guiengola

Mile 18 · Archaeological site · 2 mi from the route · side trip; actual detour depends on access roads

Guiengola is a Late Postclassic Zapotec archaeological site near Santo Domingo Tehuantepec, on high ground above the Tehuantepec River and known as a fortified settlement.

Mitla

Mile 140 · Archaeological site · 0.2 mi from the route

Mitla, the key site of Zapotec culture and Oaxaca's second major archaeological site after Monte Albán, lies 44 km from Oaxaca City at the upper end of the Tlacolula Valley.

Yagul

Mile 145 · Archaeological site · 0.9 mi from the route

On a rocky hill in Oaxaca's Tlacolula Valley, Yagul is a Zapotec site whose builders linked platforms by paths. Explore the Palace of the Six Patios, a ball court, tombs and a fortress wall with lookouts.

Lambityeco

Mile 148 · Archaeological site · 0.2 mi from the route

Lambityeco is a small Zapotec archaeological site just off Highway 190, about 3 km west of Tlacolula de Matamoros and roughly 25 km east of Oaxaca on the way to Mitla.

Museo del Ferrocarril Mexicano del Sur

Mile 166 · Museum · 0.4 mi from the route

Oaxaca City's old railroad station, built in the late 19th century, houses the Museo del Ferrocarril Mexicano del Sur, which reopened as an exhibition space in 2003.

Suchilquitongo

Mile 184 · Archaeological site · 0.3 mi from the route

From around 300 to 800 AD, a Zapotec city thrived on a hilltop in the northern Etla Valley. Locals know the site as Cerro de la Campana.

Tehuacán-Cuicatlán Biosphere Reserve

Mile 280 · Biosphere reserve · 7 mi from the route · side trip; actual detour depends on access roads

Cactus diversity reaches one of its peaks in the Tehuacán-Cuicatlán Valley, a dry landscape shared by Puebla and Oaxaca. Ancient canals, wells, terraces and dams show how people managed its scarce water.

Cholula

Mile 382 · Archaeological site · 0.6 mi from the route

Cholula's Great Pyramid grew in successive construction phases around an adobe core. INAH repair work on its Pocito staircase after the 2017 earthquakes turned up broken pre-Hispanic braziers and a small limestone figure of the rain god Tláloc.

Once you reach Huejotzingo

Convento de Huejotzingo

Convent · in Huejotzingo

Founded by Franciscans in the 16th century, the former convent of San Miguel Arcángel in Huejotzingo shows colonial Plateresque architecture on the western slopes of Popocatépetl and Iztaccíhuatl. UNESCO declared it a World Heritage Site in 1994.

More drives to Huejotzingo

From Salina Cruz to other places in Mexico

Frequently asked questions

How long is the drive from Salina Cruz to Huejotzingo?

About 7 h 46 min of driving without stops, over 392 miles.

What is the driving distance from Salina Cruz to Huejotzingo?

About 392 miles (631 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Salina Cruz to Huejotzingo?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Salina Cruz to Huejotzingo?

The U.S. State Department rates Oaxaca Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Salina Cruz to Huejotzingo use?

In order: MEX-185, MEX-190, MEX-135D, MEX-150D and MEX-150. The road-by-road table above shows the route miles for each one.

Where can you stop on the way from Salina Cruz to Huejotzingo?

Closest to the road: Mitla (archaeological site, mile 140, 0.2 mi from the route); Lambityeco (archaeological site, mile 148, 0.2 mi from the route); Suchilquitongo (archaeological site, mile 184, 0.3 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.