Rosario, Argentina to Treinta y Tres, Uruguay is about 536 road miles (863 km): roughly 11 h 33 min at the wheel if you don't stop. You cross from Argentina into Uruguay at about mile 185, at the Gualeguaychú–Fray Bentos bridge.
Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Argentina: “Gas stations are often far apart and not always easily identified from the main roadway.”
- Uruguay: “Several of the main highways are particularly accident-ridden.”
| Distance | 536 mi (863 km) |
|---|---|
| Time at the wheel, no stops | 11 h 33 min |
| Main roads, in order | RN174 → RP11 → RN12 → RP16 → RN136 |
| Border crossing | about mile 185, Argentina → Uruguay (the Gualeguaychú–Fray Bentos bridge) |
| Regions on the route | Santa Fe, Entre Ríos, Río Negro, Soriano, Colonia, San José, Canelones, Lavalleja, Treinta y Tres |
| Fuel estimate (car at 25 mpg) | about 21.4 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
Crossing from Argentina into Uruguay
The route crosses at about mile 185, at the Gualeguaychú–Fray Bentos bridge, from Entre Ríos into Río Negro. Plan on two checks on each side: immigration for your passport and customs for the car.
| Entering Uruguay (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. |
|---|---|
| Driving in Uruguay | You can drive on your U.S. license. |
| Entering Argentina (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. |
| Driving in Argentina | A valid U.S. license usually works; an International Driving Permit is recommended. |
| Rental car | Cross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book. |
Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.
On the road from Rosario to Treinta y Tres
RP11 (64 mi) and RP16 (41 mi) carry about 20% of the 536 miles. The first 185 miles are in Argentina; the last 351 are in Uruguay. It runs through 9 regions: Santa Fe, Entre Ríos, Río Negro, Soriano, Colonia, San José, Canelones, Lavalleja, Treinta y Tres. Of the 9 stops listed below, 4 are within a mile of the road.
Roads you'll take from Rosario to Treinta y Tres
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–7 | 7 | Santa Fe |
| connecting roads | 7–8 | 1 | Santa Fe |
| RN174 | 8–45 | 37 | Santa Fe, Entre Ríos |
| RP11 | 45–109 | 64 | Entre Ríos |
| RN12 | 109–114 | 5 | Entre Ríos |
| RP16 | 114–155 | 41 | Entre Ríos |
| local roads | 155–160 | 5 | Entre Ríos |
| connecting roads | 160–163 | 3 | Entre Ríos |
| RN136 | 163–182 | 19 | Entre Ríos |
| connecting roads | 182–185 | 3 | Entre Ríos |
| local roads | 185–281 | 96 | Río Negro, Soriano |
| connecting roads | 281–282 | 1 | Soriano |
| local roads | 282–318 | 36 | Colonia, San José |
| connecting roads | 318–321 | 3 | San José |
| local roads | 321–388 | 67 | San José, Canelones |
| connecting roads | 388–389 | 1 | Canelones |
| local roads | 389–536 | 147 | Canelones, Lavalleja, Treinta y Tres |
- Mile 11 of this route: Santa Fe → Entre Ríos (region line)
- Mile 185 of this route: Entre Ríos → Río Negro (international border)
- Mile 201 of this route: Río Negro → Soriano (region line)
- Mile 282 of this route: Soriano → Colonia (region line)
- Mile 300 of this route: Colonia → San José (region line)
- Mile 343 of this route: San José → Canelones (region line)
- Mile 409 of this route: Canelones → Lavalleja (region line)
- Mile 519 of this route: Lavalleja → Treinta y Tres (region line)
Stops between Rosario and Treinta y Tres
- Right off the route (under 1 mile): Abadía del Niño Dios (mile 45), Gualeguaychú Cathedral (mile 161), Cathedral of San José de Mayo (mile 319), Teatro Lavalleja (mile 433)
- Nature and outdoors: Parque nacional Arequita (mile 434), Salto del Penitente (mile 444)
- Museums and history: Gualeguaychú Cathedral (mile 161), Alejandro Berro Paleontology Museum (mile 199), Cathedral of San José de Mayo (mile 319), Iglesia de Cristo Obrero y Nuestra Señora de Lourdes (mile 389)
Abadía del Niño Dios
Abadía del Niño Dios is a Benedictine monastery in Victoria, Entre Ríos Province. Founded in 1899, it was the first Benedictine foundation in Hispanic America.
Gualeguaychú Cathedral
St. Joseph's Cathedral, also called Gualeguaychú Cathedral, is the mother church of the Roman Catholic Diocese of Gualeguaychú in Argentina.
Frigorífico Anglo del Uruguay
Part of a UNESCO World Heritage landscape inscribed in 2015, the old Anglo meatpacking plant stands on the Uruguay River at Fray Bentos, where frozen meat shipments began in 1924.
Alejandro Berro Paleontology Museum
In a 19th-century building in Mercedes' Parque Castillo Mauá, this paleontology museum opened in 1946 around the collection of naturalist Alejandro Berro; a well-preserved glyptodon shell found on a nearby riverbank is a highlight.
Cathedral of San José de Mayo
The main Catholic church of San José de Mayo, the Cathedral Basilica of St. Joseph has been the diocesan seat since 1955, a minor basilica since 1957 and Uruguay's national shrine of Saint Joseph.
Iglesia de Cristo Obrero y Nuestra Señora de Lourdes
Engineer Eladio Dieste's Church of Christ the Worker in Estación Atlántida, inaugurated in 1960, joined UNESCO's World Heritage List in 2021. Look for its wavy brick walls and roof, an openwork brick bell tower and an underground baptistery.
Teatro Lavalleja
Teatro Lavalleja is a theater complex in the city of Minas, in the Lavalleja department of Uruguay.
Parque nacional Arequita
Arequita National Park is a protected natural area in Lavalleja department, southeastern Uruguay, known for Cerro Arequita, its related rock formations and its biodiversity.
Salto del Penitente
When you get to Treinta y Tres
Museo Agustín Araújo
Treinta y Tres's departmental fine arts museum, the Museo Agustín Araújo is a public museum in the city of Treinta y Tres, Uruguay.
More drives to Treinta y Tres
- Montevideo to Treinta y Tres
- Rivera to Treinta y Tres
- Colonia del Sacramento to Treinta y Tres
- Salto to Treinta y Tres
- Fray Bentos to Treinta y Tres
- Buenos Aires to Treinta y Tres, Uruguay
More drives from Rosario
- Rosario, Argentina to La Plata
- Rosario, Argentina to Berisso
- Rosario, Argentina to Magdalena
- Rosario, Argentina to Chascomús
- Rosario, Argentina to Cariló
- Rosario, Argentina to Villa Gesell
Continue Your Adventure
Frequently asked questions
How long does it take to drive from Rosario, Argentina to Treinta y Tres, Uruguay?
About 11 h 33 min of driving without stops, over 536 miles.
What is the driving distance from Rosario, Argentina to Treinta y Tres, Uruguay?
About 536 miles (863 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Rosario to Treinta y Tres drive cross the border?
At about mile 185, from Argentina into Uruguay, at the Gualeguaychú–Fray Bentos bridge.
What do U.S. citizens need to drive from Rosario into Uruguay?
No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)
Is it safe to drive from Rosario, Argentina to Treinta y Tres, Uruguay?
The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from Rosario to Treinta y Tres?
In order: RN174, RP11, RN12, RP16 and RN136. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Rosario to Treinta y Tres?
Closest to the road: Abadía del Niño Dios (monastery, mile 45, 0.6 mi from the route); Gualeguaychú Cathedral (cathedral, mile 161, 0.8 mi from the route); Teatro Lavalleja (theater, mile 433, 0.3 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.