Plan on about 10 h 49 min of driving for the 443-mile (713 km) trip from Pereira to Sincelejo, before any stops.
Read the full advisory before you go: Colombia. Advisory issued: Colombia March 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Colombia: “Travel only during daylight hours.”
| Distance | 443 mi (713 km) |
|---|---|
| Time at the wheel, no stops | 10 h 49 min |
| Main roads, in order | 25BAN |
| Departments on the route | Risaralda, Caldas, Antioquia, Córdoba, Sucre |
| Fuel estimate (car at 25 mpg) | about 17.7 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
Driving Pereira to Sincelejo: the shape of the trip
25BAN (20 mi) carries about 5% of the 443 miles. It runs through 5 departments: Risaralda, Caldas, Antioquia, Córdoba, Sucre. Of the 8 stops listed below, 7 are within a mile of the road.
The route from Pereira to Sincelejo, road by road
| Road | Route miles (from–to) | Length, mi | Department |
|---|---|---|---|
| local roads | 0–109 | 109 | Risaralda, Caldas, Antioquia |
| 25BAN | 109–129 | 20 | Antioquia |
| local roads | 129–143 | 14 | Antioquia |
| connecting roads | 143–144 | 1 | Antioquia |
| local roads | 144–162 | 18 | Antioquia |
| connecting roads | 162–163 | 1 | Antioquia |
| local roads | 163–443 | 280 | Antioquia, Córdoba, Sucre |
- Mile 15 of this route: Risaralda → Caldas (department line)
- Mile 48 of this route: Caldas → Risaralda (department line)
- Mile 52 of this route: Risaralda → Caldas (department line)
- Mile 87 of this route: Caldas → Antioquia (department line)
- Mile 332 of this route: Antioquia → Córdoba (department line)
- Mile 428 of this route: Córdoba → Sucre (department line)
Breaking up the drive: stops between Pereira and Sincelejo
- Right off the route (under 1 mile): Basílica Menor Nuestra Señora del Rosario de Chiquinquirá, La Estrella (mile 142), El Castillo Museum (mile 148), Medellín Museum of Modern Art (mile 150), Metropolitan Cathedral of Medellín (mile 152), San Pedro Cemetery Museum (mile 153), Our Lady of the Rosary of Chiquinquirá Cathedral (mile 199), Basilica of Our Lady of Mercy (mile 229)
- Nature and outdoors: Salto Chorrolato (mile 157)
- Museums and history: Basílica Menor Nuestra Señora del Rosario de Chiquinquirá, La Estrella (mile 142), El Castillo Museum (mile 148), Medellín Museum of Modern Art (mile 150), Metropolitan Cathedral of Medellín (mile 152), San Pedro Cemetery Museum (mile 153), Our Lady of the Rosary of Chiquinquirá Cathedral (mile 199), Basilica of Our Lady of Mercy (mile 229)
Basílica Menor Nuestra Señora del Rosario de Chiquinquirá, La Estrella
Part of the Archdiocese of Medellín, this Catholic minor basilica dedicated to Our Lady of the Rosary of Chiquinquirá stands in the municipality of La Estrella, Antioquia.
El Castillo Museum
In Medellín's El Poblado district, El Castillo Museum displays porcelain and glass, stained glass, antiques, paintings and sculptures in its permanent exhibitions.
Medellín Museum of Modern Art
Medellín's Museum of Modern Art, founded in 1978, is a modern art museum in the Colombian city of Medellín.
Metropolitan Cathedral of Medellín
Officially the Metropolitan Cathedral Basilica of the Immaculate Conception, Medellín's cathedral stands in the Villanueva neighborhood on the north side of Bolívar Park.
San Pedro Cemetery Museum
Built in 1842 and named a museum in 1998, Medellín's San Pedro Cemetery Museum was declared a national monument of Colombia in 1999.
Salto Chorrolato
In the San Félix area of Bello, in the Aburrá Valley near Medellín, Salto Chorrolato (Chorro del Hato) is a multi-step waterfall and a symbol of the municipality.
Our Lady of the Rosary of Chiquinquirá Cathedral
Facing the south side of Bolívar Park in Santa Rosa de Osos, Colombia, this cathedral is dedicated to the Virgin Mary as Our Lady of the Rosary of Chiquinquirá.
Basilica of Our Lady of Mercy
A minor basilica in Yarumal, the Basilica of Our Lady of Mercy belongs to the Diocese of Santa Rosa de Osos and serves as the parish church.
When you get to Sincelejo
St. Francis of Assisi Cathedral, Sincelejo
Sincelejo Cathedral, dedicated to St. Francis of Assisi, is a cathedral church of the Catholic Church in Sincelejo, Colombia.
More drives to Sincelejo
From Pereira to other places in Colombia
- Pereira to Guatapé
- Pereira to Girardot City
- Pereira to Zipaquirá
- Pereira to Tunja
- Pereira to Sogamoso
- Pereira to Yopal
Frequently asked questions
How long is the drive from Pereira to Sincelejo?
About 10 h 49 min of driving without stops, over 443 miles.
How far is Sincelejo from Pereira by car?
About 443 miles (713 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Pereira to Sincelejo drive?
The U.S. State Department rates Colombia Level 3: Reconsider Travel. Read the full advisory before you go.
Where can you stop on the way from Pereira to Sincelejo?
Closest to the road: Medellín Museum of Modern Art (art museum, mile 150, 0.2 mi from the route); Our Lady of the Rosary of Chiquinquirá Cathedral (cathedral, mile 199, 0.4 mi from the route); Basilica of Our Lady of Mercy (basilica, mile 229, 0.5 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.