Mexico City to Tuxtepec Road Trip: Where to Stop on the Way

By admin, 3 October, 2026

The Wayro route from Mexico City to Tuxtepec is 267 miles (430 km), about 4 h 59 min of driving without stops.

U.S. State Department travel advisory: Mexico City — Level 2, Exercise Increased Caution; State of Mexico — Level 2, Exercise Increased Caution; Puebla — Level 2, Exercise Increased Caution; Veracruz — Level 2, Exercise Increased Caution; Oaxaca — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Oaxaca is the Mexican state that contains Tuxtepec. See the full advisory for current details.
Jardín Botánico Medicinal De la Cruz-BadianoIztapasauriaMuseo Comunitario de San Miguel TeotongoCasa del AlfeñiqueCañón del Río Blanco National ParkOrizaba CathedralVeracruz State Art MuseumHuatuscoMexico CityTuxtepec
Route from Mexico City to Tuxtepec with the 8 stops listed below (blue dots).
Distance267 mi (430 km)
Driving time, no stops4 h 59 min
Main roads, in orderMEX-150D → MEX-145 → MEX-175
Mexican states on the routeMexico City (Level 2), State of Mexico (Level 2), Puebla (Level 2), Veracruz (Level 2), Oaxaca (Level 2)
Toll roadsMEX-150D
Fuel estimate (car at 25 mpg)about 10.7 gal; actual use varies by vehicle and traffic
Stops listed below8

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Mexico City to Tuxtepec is like

MEX-150D (197 mi) and MEX-145 (48 mi) carry about 92% of the 267 miles. MEX-150D is a toll highway (cuota); MEX-145, MEX-175 are free federal roads (libre). It runs through 5 states: Mexico City, State of Mexico, Puebla, Veracruz, Oaxaca. Of the 8 stops listed below, 3 are within a mile of the road.

The route from Mexico City to Tuxtepec, road by road

RoadRoute miles (from–to)Length, miState
local roads0–1010Mexico City, State of Mexico
connecting roads10–111State of Mexico
MEX-150D11–208197State of Mexico, Puebla, Veracruz
connecting roads208–2113Veracruz
MEX-145211–25948Veracruz
connecting roads259–2601Veracruz
MEX-175260–2677Veracruz, Oaxaca
  • Mile 6 of this route: Mexico City → State of Mexico (state line)
  • Mile 39 of this route: State of Mexico → Puebla (state line)
  • Mile 140 of this route: Puebla → Veracruz (state line)
  • Mile 263 of this route: Veracruz → Oaxaca (state line)

Stops between Mexico City and Tuxtepec

  • Right off the route (under 1 mile): Jardín Botánico Medicinal De la Cruz-Badiano (mile 7), Museo Comunitario de San Miguel Teotongo (mile 11), Cañón del Río Blanco National Park (mile 153)
  • Nature and outdoors: Jardín Botánico Medicinal De la Cruz-Badiano (mile 7), Cañón del Río Blanco National Park (mile 153)
  • Museums and history: Museo Comunitario de San Miguel Teotongo (mile 11), Casa del Alfeñique (mile 76), Orizaba Cathedral (mile 162), Veracruz State Art Museum (mile 163), Huatusco (mile 201)
  • With kids: Iztapasauria (mile 8)

Jardín Botánico Medicinal De la Cruz-Badiano

Mile 7 · Botanical garden · 0.7 mi from the route

UNAM's De la Cruz-Badiano medicinal botanical garden in Iztapalapa is one of Mexico's early gardens devoted to medicinal plants.

Iztapasauria

Mile 8 · Theme park · 3 mi from the route · side trip; actual detour depends on access roads

Opened on December 4, 2021, Iztapasauria is a dinosaur theme park inside the Deportivo Utopía Santa Cruz Meyehualco sports complex in Iztapalapa.

Museo Comunitario de San Miguel Teotongo

Mile 11 · Museum · 0.4 mi from the route

San Miguel Teotongo's community museum sits in the San Miguel Teotongo neighborhood of the Iztapalapa borough in Mexico City.

Casa del Alfeñique

Mile 76 · Museum · 3 mi from the route · side trip; actual detour depends on access roads

Founded in 1926, the Museo Regional Casa de Alfeñique is a museum in the city of Puebla, housed in the building known as the Casa de Alfeñique.

Cañón del Río Blanco National Park

Mile 153 · National Park of Mexico · 0.5 mi from the route

Cañón del Río Blanco National Park is a protected natural area in the Mexican state of Veracruz, set aside by the government as a national park.

Orizaba Cathedral

Mile 162 · Cathedral · 1 mi from the route

The Cathedral of St. Michael the Archangel is the main Catholic church of Orizaba, in the state of Veracruz, and the seat of the Diocese of Orizaba.

Veracruz State Art Museum

Mile 163 · Art museum · 1 mi from the route

Housed in Orizaba's 18th-century former Oratorio of San Felipe Neri, later a hospital and then a jail, the Veracruz State Art Museum (Museo de Arte del Estado) holds more than 700 works, including 36 by Diego Rivera.

Huatusco

Mile 201 · Archaeological site · 2 mi from the route · side trip; actual detour depends on access roads

Above the Atoyac River in Carrillo Puerto, the ruins of Huatusco (Cuauhtochco) include a Mexica-era temple that still keeps original surface finishes. There are no visitor facilities; reaching it means crossing a suspension bridge and climbing a steep trail, ideally with a local guide.

More drives to Tuxtepec

From Mexico City to other places in Mexico

Frequently asked questions

How long is the drive from Mexico City to Tuxtepec?

About 4 h 59 min of driving without stops, over 267 miles.

How far is Tuxtepec from Mexico City by car?

About 267 miles (430 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Mexico City to Tuxtepec?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Mexico City to Tuxtepec?

The U.S. State Department rates Mexico City Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution; Oaxaca Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Mexico City to Tuxtepec use?

In order: MEX-150D, MEX-145 and MEX-175. The road-by-road table above shows the route miles and states for each one.

What are good stops between Mexico City and Tuxtepec?

Closest to the road: Jardín Botánico Medicinal De la Cruz-Badiano (botanical garden, mile 7, 0.7 mi from the route); Museo Comunitario de San Miguel Teotongo (museum, mile 11, 0.4 mi from the route); Cañón del Río Blanco National Park (National Park of Mexico, mile 153, 0.5 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.