Matehuala to San Luis Soyatlán Road Trip: Route, Tolls & Stops

By admin, 13 October, 2026

Plan on about 7 h 13 min of driving for the 369-mile (594 km) trip from Matehuala to San Luis Soyatlán, before any stops.

U.S. State Department travel advisory: San Luis Potosí — Level 2, Exercise Increased Caution; Guanajuato — Level 3, Reconsider Travel; Jalisco — Level 3, Reconsider TravelAdvisory issued May 29, 2026; checked September 29, 2026. Jalisco is the Mexican state that contains San Luis Soyatlán. Check the full advisory for this state before you go.
Casa Museo Manuel José OthónMuseo Laberinto de las Ciencias y las ArtesMuseo de los Altos de Jalisco, Casa Agustín RiveraTeatro José Rosas MorenoCathedral Basilica of San Juan de los LagosTeocaltitan Archaeological SiteConvento de Nuestra Señora del Perpetuo SocorroUniversidad de Guadalajara. Museo de las ArtesEl IxtépeteMatehualaSan Luis Soyatlán
Route from Matehuala to San Luis Soyatlán with the 9 stops listed below (blue dots).
Total distance369 mi (594 km)
Drive time without stops7 h 13 min
Main roads, in orderMEX-57 → MEX-57D → MEX-70 → MEX-80 → MEX-80D → MEX-15D → MEX-15
Mexican states on the routeSan Luis Potosí, Guanajuato, Jalisco
Toll roads (as marked in OpenStreetMap)MEX-57D, MEX-80D, MEX-90D, MEX-15D
Fuel estimate (car at 25 mpg)about 14.8 gal; actual use varies by vehicle and traffic
Stops listed below9

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

How the Matehuala to San Luis Soyatlán drive plays out

MEX-80D (127 mi) and MEX-57 (94 mi) carry about 60% of the 369 miles. It runs through 3 states: San Luis Potosí, Guanajuato, Jalisco. OpenStreetMap marks tolled sections on MEX-57D, MEX-80D and MEX-90D. Of the 9 stops listed below, 2 are within a mile of the road.

Which roads connect Matehuala and San Luis Soyatlán

RoadRoute miles (from–to)Length, miState
local roads0–22San Luis Potosí
MEX-572–8078San Luis Potosí
MEX-57D80–10121San Luis Potosí
MEX-57101–11716San Luis Potosí
local roads117–12710San Luis Potosí
MEX-57D127–1369San Luis Potosí
MEX-70136–15317San Luis Potosí
MEX-80153–1574San Luis Potosí
MEX-80D157–19841San Luis Potosí, Guanajuato, Jalisco
MEX-80198–23133Jalisco
MEX-80D231–31786Jalisco
MEX-15D317–3225Jalisco
local roads322–3264Jalisco
MEX-15326–36842Jalisco
local roads368–3691Jalisco
  • Mile 163 of this route: San Luis Potosí → Guanajuato (state line)
  • Mile 174 of this route: Guanajuato → Jalisco (state line)

What to see on the way from Matehuala to San Luis Soyatlán

  • Right off the route (under 1 mile): Museo de los Altos de Jalisco, Casa Agustín Rivera (mile 207), Teatro José Rosas Moreno (mile 208)
  • Museums and history: Casa Museo Manuel José Othón (mile 119), Museo Laberinto de las Ciencias y las Artes (mile 121), Museo de los Altos de Jalisco, Casa Agustín Rivera (mile 207), Teatro José Rosas Moreno (mile 208), Cathedral Basilica of San Juan de los Lagos (mile 236), Teocaltitan Archaeological Site (mile 244), Universidad de Guadalajara. Museo de las Artes (mile 322), El Ixtépete (mile 327)

Casa Museo Manuel José Othón

Mile 119 · Museum · 1 mi from the route

Near Plaza del Carmen in San Luis Potosí, poet Manuel José Othón's birthplace opened as a museum on November 28, 1966, covering his life and work.

Museo Laberinto de las Ciencias y las Artes

Mile 121 · Museum · 3 mi from the route · side trip; actual detour depends on access roads

Built in Parque Tangamanga I and opened on September 4, 2008, the Museo Laberinto de las Ciencias y las Artes is an interactive museum in San Luis Potosí.

Museo de los Altos de Jalisco, Casa Agustín Rivera

Mile 207 · Museum · 0.4 mi from the route

The Museo Casa Agustín Rivera Altos de Jalisco is a museum you'll find in the town of Lagos de Moreno, in the state of Jalisco.

Teatro José Rosas Moreno

Mile 208 · Opera house · 0.3 mi from the route

Construction of the Teatro José Rosas Moreno in Lagos de Moreno began in 1867, and the theater opened on May 5, 1907. It is named for Jalisco writer José Rosas Moreno.

Cathedral Basilica of San Juan de los Lagos

Mile 236 · Basilica · 2 mi from the route · side trip; actual detour depends on access roads

Raised between 1732 and 1769, the cathedral basilica of San Juan de los Lagos draws pilgrims from far away who come to visit the small image of the Virgin kept inside.

Teocaltitan Archaeological Site

Mile 244 · Archaeological site · 2 mi from the route · side trip; actual detour depends on access roads

Pyramids, sunken patios and a ball court spread over roughly nine hectares at Teocaltitán, close to Jalostotitlán in the Los Altos region.

Convento de Nuestra Señora del Perpetuo Socorro

Mile 322 · Convent · 1 mi from the route

Better known as El Perpetuo Socorro, this Guadalajara church is home to a Passionist convent that has housed the order's postulants since 2020.

Universidad de Guadalajara. Museo de las Artes

Mile 322 · Museum · 2 mi from the route

The University of Guadalajara's Museo de las Artes, known as MUSA, opened on October 10, 1994, and was expanded in 2013.

El Ixtépete

Mile 327 · Archaeological site · 1 mi from the route

Zapopan's El Ixtépete preserves a pyramid built around AD 650-750, during the Grillo tradition, with at least seven superimposed construction phases; the site lies within the Guadalajara metro area near the Periférico and Avenida Mariano Otero.

More drives to San Luis Soyatlán

From Matehuala to other places in Mexico

Frequently asked questions

How long is the drive from Matehuala to San Luis Soyatlán?

About 7 h 13 min of driving without stops, over 369 miles.

How far is San Luis Soyatlán from Matehuala by car?

About 369 miles (594 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Matehuala to San Luis Soyatlán?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Matehuala to San Luis Soyatlán?

The U.S. State Department rates San Luis Potosí Level 2: Exercise Increased Caution; Guanajuato Level 3: Reconsider Travel; Jalisco Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.

Which highways go from Matehuala to San Luis Soyatlán?

In order: MEX-57, MEX-57D, MEX-70, MEX-80, MEX-80D, MEX-15D and MEX-15. The road-by-road table above shows the route miles for each one.

Where can you stop on the way from Matehuala to San Luis Soyatlán?

Closest to the road: Museo de los Altos de Jalisco, Casa Agustín Rivera (museum, mile 207, 0.4 mi from the route); Teatro José Rosas Moreno (opera house, mile 208, 0.3 mi from the route); Convento de Nuestra Señora del Perpetuo Socorro (convent, mile 322, 1 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.