By road, Los Ángeles and Portillo are about 412 miles (663 km) apart, or roughly 8 h 0 min of driving.
Full advisory: Chile. Advisory issued: Chile August 19, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Chile: “Secondary and mountain roads may be poorly maintained, poorly lit, and may lack guardrails.”
| Distance | 412 mi (663 km) |
|---|---|
| Driving time, no stops | 8 h 0 min |
| Main roads, in order | E-57 → E-61 → E-773 |
| Regions on the route | Bío-Bío, Ñuble, Maule, Libertador General Bernardo O'Higgins, Región Metropolitana de Santiago, Valparaíso |
| Fuel estimate (car at 25 mpg) | about 16.5 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
On the road from Los Ángeles to Portillo
E-61 (5 mi) and E-773 (4 mi) carry about 2% of the 412 miles. It runs through 6 regions: Bío-Bío, Ñuble, Maule, Libertador General Bernardo O'Higgins, Región Metropolitana de Santiago, Valparaíso. Of the 9 stops listed below, 4 are within a mile of the road.
Roads you'll take from Los Ángeles to Portillo
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–323 | 323 | Bío-Bío, Ñuble, Maule, Libertador General Bernardo O'Higgins, Región Metropolitana de Santiago |
| connecting roads | 323–325 | 2 | Región Metropolitana de Santiago |
| local roads | 325–362 | 37 | Región Metropolitana de Santiago, Valparaíso |
| E-57 | 362–365 | 3 | Valparaíso |
| connecting roads | 365–368 | 3 | Valparaíso |
| E-61 | 368–373 | 5 | Valparaíso |
| local roads | 373–408 | 35 | Valparaíso |
| E-773 | 408–412 | 4 | Valparaíso |
- Mile 40 of this route: Bío-Bío → Ñuble (region line)
- Mile 101 of this route: Ñuble → Maule (region line)
- Mile 213 of this route: Maule → Libertador General Bernardo O'Higgins (region line)
- Mile 283 of this route: Libertador General Bernardo O'Higgins → Región Metropolitana de Santiago (region line)
- Mile 352 of this route: Región Metropolitana de Santiago → Valparaíso (region line)
Stops between Los Ángeles and Portillo
- Right off the route (under 1 mile): Laja Falls (mile 21), Teatro Victoria (mile 200), Museo de Ciencia y Tecnología (mile 319), Santuario de Santa Teresa de Los Andes (mile 360)
- Nature and outdoors: Laja Falls (mile 21), Museo de Ciencia y Tecnología (mile 319), Río Blanco National Reserve (mile 386)
- Museums and history: Museo Marta Colvin (mile 71), Museo de Arte y Artesanía de Linares (mile 131), Museo Regional de Rancagua (mile 264), Museo de Ciencia y Tecnología (mile 319)
Laja Falls
Beside Ruta 5 about 25 km from Los Ángeles, the Laja River pours over four cascades up to roughly 35 meters high, cut into basalt left by ancient lava flows from the Antuco volcano.
Museo Marta Colvin
On the Fernando May campus of the Universidad del Bío-Bío in Chillán, Museo Marta Colvin presents the life and work of local sculptor Marta Colvin. It opened on July 15, 2011.
Museo de Arte y Artesanía de Linares
Founded in 1962 with works donated by Chilean artists, this museum in Linares, in Chile's Maule Region, specializes in art and crafts.
Teatro Regional del Maule
Known as the TRM, the Teatro Regional del Maule in Talca opened on September 5, 2005, and its main hall seats 1,028 people.
Teatro Victoria
Museo Regional de Rancagua
Museo Regional de Rancagua is the main public museum of the O'Higgins Region, housed in two colonial-era mansions on Paseo del Estado: Casa del Ochavo and Casa del Pilar de Esquina.
Museo de Ciencia y Tecnología
Inside Santiago's Parque Quinta Normal, the Museum of Science and Technology is run by a private corporation that promotes science and technology.
Santuario de Santa Teresa de Los Andes
Pilgrims come to the Santuario de Santa Teresa de Los Andes in Rinconada, Valparaíso Region, to venerate the relics of Saint Teresa of the Andes, Chile's first saint. The shrine was built to receive thousands of the faithful.
Río Blanco National Reserve
Río Blanco National Reserve is a protected area in Chile's Valparaíso Region, about 60 kilometers northeast of Santiago.
More drives to Portillo
- Santiago, Chile to Portillo
- El Colorado to Portillo
- Viña del Mar to Portillo
- Valparaíso to Portillo
- Algarrobo to Portillo
- Coquimbo to Portillo
From Los Ángeles to other places in Chile
- Los Ángeles to Pelluhue
- Los Ángeles to Curicó
- Los Ángeles to Santa Cruz, Chile
- Los Ángeles to Pichilemu
- Los Ángeles to El Colorado
- Los Ángeles to Valle Nevado
Frequently asked questions
How long does it take to drive from Los Ángeles to Portillo?
About 8 h 0 min of driving without stops, over 412 miles.
How far is Portillo from Los Ángeles by car?
About 412 miles (663 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Los Ángeles to Portillo drive?
The U.S. State Department rates Chile Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Los Ángeles to Portillo use?
In order: E-57, E-61 and E-773. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Los Ángeles to Portillo?
Closest to the road: Laja Falls (waterfall, mile 21, 0.4 mi from the route); Museo de Ciencia y Tecnología (natural history museum, mile 319, 0.6 mi from the route); Santuario de Santa Teresa de Los Andes (convent of discalced carmelite nuns, mile 360, 0.5 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.