Plan on about 6 h 48 min of driving for the 367-mile (591 km) trip from Los Ángeles to Los Andes, before any stops.
Full advisory: Chile. Advisory issued: Chile August 19, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Chile: “Secondary and mountain roads may be poorly maintained, poorly lit, and may lack guardrails.”
| Distance | 367 mi (591 km) |
|---|---|
| Drive time without stops | 6 h 48 min |
| Main roads, in order | E-57 |
| Regions on the route | Bío-Bío, Ñuble, Maule, Libertador General Bernardo O'Higgins, Región Metropolitana de Santiago, Valparaíso |
| Fuel estimate (car at 25 mpg) | about 14.7 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
The Los Ángeles–Los Andes drive in a few lines
E-57 (3 mi) carries about 1% of the 367 miles. It runs through 6 regions: Bío-Bío, Ñuble, Maule, Libertador General Bernardo O'Higgins, Región Metropolitana de Santiago, Valparaíso. Of the 9 stops listed below, 3 are within a mile of the road.
Road-by-road breakdown: Los Ángeles to Los Andes
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–323 | 323 | Bío-Bío, Ñuble, Maule, Libertador General Bernardo O'Higgins, Región Metropolitana de Santiago |
| connecting roads | 323–325 | 2 | Región Metropolitana de Santiago |
| local roads | 325–362 | 37 | Región Metropolitana de Santiago, Valparaíso |
| E-57 | 362–365 | 3 | Valparaíso |
| local roads | 365–367 | 2 | Valparaíso |
- Mile 40 of this route: Bío-Bío → Ñuble (region line)
- Mile 101 of this route: Ñuble → Maule (region line)
- Mile 213 of this route: Maule → Libertador General Bernardo O'Higgins (region line)
- Mile 283 of this route: Libertador General Bernardo O'Higgins → Región Metropolitana de Santiago (region line)
- Mile 352 of this route: Región Metropolitana de Santiago → Valparaíso (region line)
What to see on the way from Los Ángeles to Los Andes
- Right off the route (under 1 mile): Laja Falls (mile 21), Teatro Victoria (mile 200), Museo Infantil (mile 319)
- Nature and outdoors: Laja Falls (mile 21), Laguna Piedra Roja (mile 332)
- Museums and history: St. Bartholomew Cathedral, Chillán (mile 70), Museo de Arte y Artesanía de Linares (mile 131), Museo Colonial (mile 318), Museo Infantil (mile 319)
Laja Falls
Beside Ruta 5 about 25 km from Los Ángeles, the Laja River pours over four cascades up to roughly 35 meters high, cut into basalt left by ancient lava flows from the Antuco volcano.
St. Bartholomew Cathedral, Chillán
Chillán Cathedral, dedicated to St. Bartholomew, is the seat of the Diocese of Chillán and stands in the city center opposite the Plaza de Armas, at Arauco and Libertad streets.
Museo de Arte y Artesanía de Linares
Founded in 1962 with works donated by Chilean artists, this museum in Linares, in Chile's Maule Region, specializes in art and crafts.
Teatro Regional del Maule
Known as the TRM, the Teatro Regional del Maule in Talca opened on September 5, 2005, and its main hall seats 1,028 people.
Teatro Victoria
Teatro Regional Lucho Gatica
In Rancagua, Teatro Regional Lucho Gatica is a theater devoted to the performing arts.
Museo Colonial
Paintings, sculpture and furniture from the colonial period fill Museo Colonial, a historical and religious museum in Santiago devoted to colonial Chile and South America.
Museo Infantil
Located in Santiago's Parque Quinta Normal, the Museo Infantil is a museum run by a private corporation that promotes science and technology.
Laguna Piedra Roja
Laguna Piedra Roja is an artificial lagoon in Chicureo, in the Colina commune of Chile's Santiago Metropolitan Region.
In Los Andes itself
Museo y Centro Cultural Presidente Pedro Aguirre Cerda
In Pocuro, in the commune of Calle Larga, this museum and cultural center occupies the house where President Pedro Aguirre Cerda was born, plus a former agricultural school. Both buildings became national monuments in 1972.
Museo Arqueológico de Los Andes
Opened in 1969 by Carlos Coros, the Los Andes Archaeological Museum occupies a 19th-century house and holds a collection tied to the Aconcagua culture and the Inca civilization.
Corazon Thermal Baths
In Chile's Valparaíso Region, the Corazón Thermal Baths (Baños Corazón) are hot springs whose waters have been used for medicinal purposes.
More drives to Los Andes
- Santiago, Chile to Los Andes
- Viña del Mar to Los Andes
- Coquimbo to Los Andes
- La Serena to Los Andes
- Copiapó to Los Andes
- Rancagua to Los Andes
From Los Ángeles to other places in Chile
- Los Ángeles to Pelluhue
- Los Ángeles to Curicó
- Los Ángeles to Santa Cruz, Chile
- Los Ángeles to Pichilemu
- Los Ángeles to El Colorado
- Los Ángeles to Valle Nevado
Continue Your Adventure
Frequently asked questions
How long does it take to drive from Los Ángeles to Los Andes?
About 6 h 48 min of driving without stops, over 367 miles.
How far is Los Andes from Los Ángeles by car?
About 367 miles (591 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Los Ángeles to Los Andes drive?
The U.S. State Department rates Chile Level 2: Exercise Increased Caution. Read the full advisory before you go.
Where can you stop on the way from Los Ángeles to Los Andes?
Closest to the road: Laja Falls (waterfall, mile 21, 0.4 mi from the route); Teatro Victoria (theater, mile 200, 0.9 mi from the route); Museo Infantil (museum, mile 319, 0.6 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.