By road, Santiago, Chile and Los Andes are about 50 miles (81 km) apart, or roughly 1 h 10 min of driving.
Full advisory: Chile. Advisory issued: Chile August 19, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Chile: “Secondary and mountain roads may be poorly maintained, poorly lit, and may lack guardrails.”
| Distance by road | 50 mi (81 km) |
|---|---|
| Driving time, no stops | 1 h 10 min |
| Main roads, in order | E-57 |
| Regions on the route | Región Metropolitana de Santiago, Valparaíso |
| Fuel estimate (car at 25 mpg) | about 2.0 gal; actual use varies by vehicle and traffic |
| Stops listed below | 3 |
Driving Santiago to Los Andes: the shape of the trip
E-57 (4 mi) carries about 8% of the 50 miles. It runs through 2 regions: Región Metropolitana de Santiago, Valparaíso. Of the 3 stops listed below, 1 are within a mile of the road.
The route from Santiago to Los Andes, road by road
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–7 | 7 | Región Metropolitana de Santiago |
| connecting roads | 7–9 | 2 | Región Metropolitana de Santiago |
| local roads | 9–45 | 36 | Región Metropolitana de Santiago, Valparaíso |
| E-57 | 45–49 | 4 | Valparaíso |
| local roads | 49–50 | 1 | Valparaíso |
- Mile 36 of this route: Región Metropolitana de Santiago → Valparaíso (region line)
Stops between Santiago and Los Andes
- Right off the route (under 1 mile): Santuario de Santa Teresa de Los Andes (mile 44)
- Nature and outdoors: Laguna Piedra Roja (mile 16), Colina Thermal Baths (mile 22)
Laguna Piedra Roja
Laguna Piedra Roja is an artificial lagoon in Chicureo, in the Colina commune of Chile's Santiago Metropolitan Region.
Colina Thermal Baths
In the north of Chile's Santiago Metropolitan Region, the Colina Thermal Baths (Baños de Colina) are hot springs on the Colina River used for both medicinal and tourist purposes.
Santuario de Santa Teresa de Los Andes
Pilgrims come to the Santuario de Santa Teresa de Los Andes in Rinconada, Valparaíso Region, to venerate the relics of Saint Teresa of the Andes, Chile's first saint. The shrine was built to receive thousands of the faithful.
When you get to Los Andes
Museo Arqueológico de Los Andes
Opened in 1969 by Carlos Coros, the Los Andes Archaeological Museum occupies a 19th-century house and holds a collection tied to the Aconcagua culture and the Inca civilization.
Museo y Centro Cultural Presidente Pedro Aguirre Cerda
In Pocuro, in the commune of Calle Larga, this museum and cultural center occupies the house where President Pedro Aguirre Cerda was born, plus a former agricultural school. Both buildings became national monuments in 1972.
Corazon Thermal Baths
In Chile's Valparaíso Region, the Corazón Thermal Baths (Baños Corazón) are hot springs whose waters have been used for medicinal purposes.
More drives to Los Andes
- Viña del Mar to Los Andes
- Coquimbo to Los Andes
- La Serena to Los Andes
- Copiapó to Los Andes
- Rancagua to Los Andes
- Curicó to Los Andes
From Santiago to other places in Chile
- Santiago, Chile to Valparaíso
- Santiago, Chile to Quintay
- Santiago, Chile to Reñaca
- Santiago, Chile to La Serena
- Santiago, Chile to Vicuña
- Santiago, Chile to Pisco Elqui
Frequently asked questions
How long is the drive from Santiago, Chile to Los Andes?
About 1 h 10 min of driving without stops, over 50 miles.
What is the driving distance from Santiago, Chile to Los Andes?
About 50 miles (81 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Santiago, Chile to Los Andes?
The U.S. State Department rates Chile Level 2: Exercise Increased Caution. Read the full advisory before you go.
Where can you stop on the way from Santiago to Los Andes?
Closest to the road: Laguna Piedra Roja (lagoon, mile 16, 4 mi from the route); Colina Thermal Baths (hot spring, mile 22, 3 mi from the route); Santuario de Santa Teresa de Los Andes (convent of discalced carmelite nuns, mile 44, 0.6 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.